Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Myles Cabot"'
Autor:
B. Bishal Paudel, Su-Fern Tan, Todd E. Fox, Johnson Ung, Jeremy Shaw, Wendy Dunton, Irene Lee, Arati Sharma, Aaron D. Viny, Brian M. Barth, Martin S. Tallman, Myles Cabot, Francine E. Garrett-Bakelman, Ross L. Levine, Mark Kester, David Claxton, David J. Feith, Kevin A. Janes, Thomas P. Loughran
Publikováno v:
bioRxiv
Acute myeloid leukemia (AML) is an aggressive disease with complex and heterogeneous biology. Although several genomic classifications have been proposed, there is a growing interest in going beyond genomics to stratify AML. In this study, we profile
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d818fb462fe8955009591cb49d720dd6
https://europepmc.org/articles/PMC10153188/
https://europepmc.org/articles/PMC10153188/
Autor:
Kelsey H. Fisher-Wellman, James T Hagen, Miki Kassai, Li-Pin Kao, Margaret Nelson, Kelsey McLaughlin, Hannah Coalson, Todd Fox, Su-Fern Tan, David Feith, Mark Kester, Thomas Loughran, David Claxton, Myles Cabot
Modifications in sphingolipid (SL) metabolism and mitochondrial bioenergetics are key factors implicated in cancer cell response to chemotherapy, including chemotherapy resistance. Vinca alkaloids such as vincristine (VCR), widely used in cancer trea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9ff5c7419d02e11105acdddf8e6deebf
https://doi.org/10.21203/rs.3.rs-506642/v3
https://doi.org/10.21203/rs.3.rs-506642/v3
Autor:
Margaret Nelson, Kelsey McLaughlin, James Hagen, Hannah Coalson, Cameron Schmidt, Miki Kassai, Kimberly Kew, Joseph McClung, P. Neufer, Patricia Brophy, Nasreen Vohra, Darla Liles, Myles Cabot, Kelsey Fisher-Wellman
Typified by oxidative phosphorylation (OXPHOS), mitochondria catalyze a wide variety of cellular processes seemingly critical for malignant growth. As such, there is considerable interest in targeting mitochondrial metabolism in cancer. However, notw
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f75f6f8ae899ea70924b7f21c74132bb
https://doi.org/10.21203/rs.3.rs-64203/v2
https://doi.org/10.21203/rs.3.rs-64203/v2
Autor:
Guy Gammon, Peter D. Boasberg, Michael W. DeGregorio, Steven J. O'Day, Tim S. Kristedja, Patricia Fournier, Myles Cabot, Maureen Martin, He-Jing Wang
Publikováno v:
Cancer. 92:609-619
BACKGROUND In vitro cell culture data and preclinical models suggest that tamoxifen modulates tumor cell sensitivity to a wide range of therapeutic agents. In the current study, the authors examined whether high-dose tamoxifen (HDT) improved the over
Publikováno v:
Cancer. 86:300-311
BACKGROUND To provide insight for the development of more effective clinical agents, the authors attempted to elucidate the mechanisms of action of multidrug resistance (MDR) modulators. Previously, the authors found that MDR modulators blocked the c
Publikováno v:
JNCI Journal of the National Cancer Institute. 91:1138-1146
Background: The synthetic retinoid N-(4-hydroxyphenyl)retinamide (4-HPR or fenretinide) is toxic to myeloid leukemia and cervical carcinoma cell lines, probably in part due to its ability to increase levels of reactive oxygen species (ROS). We have s
Publikováno v:
Proceedings of the National Academy of Sciences. 87:7385-7389
Metabolism of inositol phospholipids and phosphatidylcholine was investigated in tracheobronchial epithelial cells exposed to mitogenic concentrations of crocidolite asbestos. Alterations in levels of diacylglycerol, the endogenous activator of prote