Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Myles Astor"'
Publikováno v:
World Journal of Urology. 3:126-130
For the past 25 years, there have been repeated efforts at improving the effectiveness of radiation therapy by combining it with various sensitizing agents. The problem has not been that these agents did not work, but rather that to be effective, the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::17623fcde926b1fede0e5e8af7b4bba2
https://doi.org/10.1007/bf00326721
https://doi.org/10.1007/bf00326721
Publikováno v:
International Journal of Radiation Oncology*Biology*Physics. 8:75-83
Chinese hamster cells in culture were used to compare the radiosensitizing efficiency and cytotoxicity of misonidazole with several 2, 4 and 5 substituted nitroimidazoles. The two substituted compounds (SR 2508 and SR 2555) are similar to misonidazol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5b46a94b038955ad73baf615426c60f
https://doi.org/10.1016/0360-3016(82)90388-1
https://doi.org/10.1016/0360-3016(82)90388-1
Autor:
Myles Astor, T.D. Morse
Publikováno v:
International Journal of Radiation Biology. 55:631-639
Potentially lethal damage repair (PLDR) was investigated in two normal and three ataxia telangiectasia (AT) human-skin fibroblast cell lines cultured in vitro. Using plateau-phase cells, both the time kinetics and the amount of repair were measured a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a5b2bfa371d0854d3bff19a84c5c0e0
https://doi.org/10.1080/09553008914550671
https://doi.org/10.1080/09553008914550671
Publikováno v:
International Journal of Radiation Oncology*Biology*Physics. 8:447-451
Electron affinic compounds, such as misonidazole, preferentially sensitize hypoxic cells to killing by X rays, and are also preferentially cytotoxic to cells deficient in oxygen. Prolonged exposure of cells to misonidazole prior to irradiation result
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::852e642d16a41df995c9ed79c0cdc4d2
https://doi.org/10.1016/0360-3016(82)90658-7
https://doi.org/10.1016/0360-3016(82)90658-7
Publikováno v:
International Journal of Radiation Oncology*Biology*Physics. 10:1221-1227
We have measured the rate of GSH resynthesis in plateau phase cultures of A549 human lung carcinoma cells subjected to a fresh medium change. Buthionine sulfoximine (BSO) blocks this resynthesis. Diethyl maleate (DEM) causes a decrease in accumulatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b785fdca87c00bdba7ff9c9b7002c7a7
https://doi.org/10.1016/0360-3016(84)90322-5
https://doi.org/10.1016/0360-3016(84)90322-5
Autor:
D. E. Bonnett, Marco Zaider, D. K. Bewley, S. W. Blake, Myles Astor, Eric J. Hall, B. M. Cullen
Publikováno v:
The British Journal of Radiology. 62:344-347
Chinese hamster V79 cells have been used to assess changes in RBE of the p(62)Be neutron beam at the Clatterbridge Hospital with depth in a phantom and with use of a hydrogenous filter. The cells were exposed at depths of 2 and 12 cm and at a depth o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3a603fe280e5d002c0b754f7b75c0ec
https://doi.org/10.1259/0007-1285-62-736-344
https://doi.org/10.1259/0007-1285-62-736-344
Publikováno v:
British Journal of Cancer
The selective cytotoxicity which Ro-07-0582 exhibits towards hypoxic cells is strongly temperature-dependent. This cytotoxicity is reduced by the radical scavenger cysteamine, suggesting that nitro radicals or nitroso intermediates are involved in ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::322edd42264dc33eb8c017adec3e9dbd
https://doi.org/10.1038/bjc.1977.122
https://doi.org/10.1038/bjc.1977.122
Publikováno v:
The British Journal of Radiology. 55:640-644
Mammalian cells cultured in vitro were used to study the radiobiological characteristics of neutron beams generated by 43 MeV protons on beryllium or 25 MeV deutrons on beryllium. For an unfiltered beam of neutrons generated by 43 MeV p+→Be the rel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2b583e6164bd51f9e48cdcd27f0c6527
https://doi.org/10.1259/0007-1285-55-657-640
https://doi.org/10.1259/0007-1285-55-657-640
Publikováno v:
British Journal of Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ce8d59f9335c5c501f418a52ef323ed
https://doi.org/10.1038/bjc.1983.18
https://doi.org/10.1038/bjc.1983.18
Publikováno v:
The British journal of radiology. 50(597)
Neutron beams currently used for radiotherapy range from 16 MeV deuterons on beryllium at Hammersmith to 67 MeV protons on beryllium at the Fermilab; over this range the oxygen enhancement ratio (OER) appears to be constant at about 1.6 (Hall, 1975a,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::252952aaf5b33792acd751f4f1a1b7d1
https://pubmed.ncbi.nlm.nih.gov/901986
https://pubmed.ncbi.nlm.nih.gov/901986