High dose CD11c-driven IL15 is sufficient to drive NK cell maturation and anti-tumor activity in a trans-presentation independent manner

Autor: Christina Vock, Diego A. Goyeneche-Patino, Mylene Divivier, Julia K Polansky, Erwin Hans Duitman, Silvia Bulfone-Paus, Zane Orinska, Rajia Bahri

Publikováno v: Polansky, J K, Bahri, R, Divivier, M, Duitman, E H, Vock, C, Goyeneche-Patino, D A, Orinska, Z & Bulfone-Paus, S 2016, ' High dose CD11c-driven IL15 is sufficient to drive NK cell maturation and anti-tumor activity in a trans-presentation independent manner ', Scientific Reports, vol. 6, pp. 19699 . https://doi.org/10.1038/srep19699
Scientific Reports

The common gamma (γc)-chain cytokine interleukin 15 (IL15) is a multifunctional immune-modulator which impacts the generation, maturation and activity of many cell types of the innate, as well as the adaptive immune system, including natural killer

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