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Akademický článek
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Autor:
Marc S. Ernstoff, Ronald H. Blum, Thomas J. Smith, Ernest C. Borden, Myla Hunt Strawderman, John M. Kirkwood
Publikováno v:
Journal of Clinical Oncology. 14:7-17
PURPOSE Interferon alfa-2b (IFN alpha-2b) exhibits antitumor activity in metastatic melanoma and on this basis has been evaluated as an adjuvant therapy following surgery for deep primary (T4) or regionally metastatic (N1) melanoma. METHODS A randomi
Autor:
Anthony D. Elias, Lois J. Ayash, J. Paul Eder, Cathy Wheeler, Joan Deary, Lisa Weissman, Myla Hunt, John Critchlow, Lowell Schnipper, Emil Frei, Karen H. Antman
Publikováno v:
Journal of Cancer Research and Clinical Oncology. 117:S208-S213
In this phase I study, 16 adult cancer patients were treated with concurrent 4-day continuous infusions of ifosfamide at 12 g/m2 and escalating doses of carboplatin (400-1600 mg/m2) to determine the major non-haematological dose-limiting toxicity of
Autor:
Myla Hunt Strawderman, Roland T. Skeel, Steven J Jubelirer, David Parkinson, Martin M. Oken, Howard S. Hochster, Jules E. Harris, Michael B. Atkins
Publikováno v:
Anti-cancer drugs. 10(2)
Despite reports that i.v. melphalan is active in the settings of conditioning regimens utilizing high-dose chemotherapy for autologous bone marrow transplantation and in isolated limb perfusion for the treatment of malignant melanoma, its activity at