Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Mylène Vaillancourt"'
Publikováno v:
Respiratory Research, Vol 21, Iss 1, Pp 1-14 (2020)
Abstract Pulmonary hypertension (PH) developing secondarily in pulmonary fibrosis (PF) patients (PF-PH) is a frequent co-morbidity. The high prevalence of PH in PF patients is very concerning since the presence of PH is a strong predictor of mortalit
Externí odkaz:
https://doaj.org/article/05a8cd02924c430799af1b7153de6c87
Autor:
Mylène Vaillancourt, Pamela Chia, Shervin Sarji, Jason Nguyen, Nir Hoftman, Gregoire Ruffenach, Mansoureh Eghbali, Aman Mahajan, Soban Umar
Publikováno v:
Respiratory Research, Vol 18, Iss 1, Pp 1-15 (2017)
Abstract Pulmonary arterial hypertension (PAH) is a chronic pulmonary vascular disease characterized by increased pulmonary vascular resistance (PVR) leading to right ventricular (RV) failure. Autonomic nervous system involvement in the pathogenesis
Externí odkaz:
https://doaj.org/article/91ef8f90c1f24f008c3127e1dac2dd1e
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e75099 (2013)
The reduction of pre-enkephalin (pENK) mRNA expression might be an early sign of striatal neuronal dysfunction in Huntington's disease (HD), due to mutated huntingtin protein. Indeed, striatopallidal (pENK-containing) neurodegeneration occurs at earl
Externí odkaz:
https://doaj.org/article/db206875f3134c33a21bc8fb5290595c
Autor:
Mylene Vaillancourt, Anna Clara Milesi Galdino, Sam P Limsuwannarot, Diana Celedonio, Elizabeth Dimitrova, Matthew Broerman, Catherine Bresee, Yohei Doi, Janet S Lee, William C Parks, Peter Jorth
Publikováno v:
PLoS Pathogens, Vol 19, Iss 4, p e1010942 (2023)
During chronic cystic fibrosis (CF) infections, evolved Pseudomonas aeruginosa antibiotic resistance is linked to increased pulmonary exacerbations, decreased lung function, and hospitalizations. However, the virulence mechanisms underlying worse out
Externí odkaz:
https://doaj.org/article/3e674c7825044a059daca663bb21bc6c
Publikováno v:
PLoS ONE
Scopus-Elsevier
PLoS ONE, Vol 8, Iss 9, p e75099 (2013)
Scopus-Elsevier
PLoS ONE, Vol 8, Iss 9, p e75099 (2013)
The reduction of pre-enkephalin (pENK) mRNA expression might be an early sign of striatal neuronal dysfunction in Huntington's disease (HD), due to mutated huntingtin protein. Indeed, striatopallidal (pENK-containing) neurodegeneration occurs at earl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::452cdd35fdf30bbbed278d0f73810ac5
https://pubmed.ncbi.nlm.nih.gov/24040390
https://pubmed.ncbi.nlm.nih.gov/24040390
Autor:
Gregoire Ruffenach, Soban Umar, Mylene Vaillancourt, Jason Hong, Nancy Cao, Shervin Sarji, Shayan Moazeni, Christine M Cunningham, Abbas Ardehali, Srinivasa T Reddy, Rajan Saggar, Gregory Fishbein, Mansoureh Eghbali
Publikováno v:
EMBO Molecular Medicine, Vol 11, Iss 9, Pp 1-19 (2019)
Abstract Pulmonary hypertension secondary to pulmonary fibrosis (PF‐PH) is one of the most common causes of PH, and there is no approved therapy. The molecular signature of PF‐PH and underlying mechanism of why pulmonary hypertension (PH) develop
Externí odkaz:
https://doaj.org/article/e06b37c3ad3342498cbb6d5a007c42db
Autor:
Mylene Vaillancourt, Peter Jorth
Publikováno v:
mBio, Vol 11, Iss 4 (2020)
ABSTRACT Coronavirus disease 2019 (COVID-19) is the greatest pandemic of our generation, with 16 million people affected and 650,000 deaths worldwide so far. One of the risk factors associated with COVID-19 is secondary bacterial pneumonia. In recent
Externí odkaz:
https://doaj.org/article/d776fedf15484f08a9a133f821d1f74e
Autor:
Mylene Vaillancourt, Sam P. Limsuwannarot, Catherine Bresee, Rahgavi Poopalarajah, Peter Jorth
Publikováno v:
Antibiotics, Vol 10, Iss 10, p 1164 (2021)
Antibiotic-resistant Pseudomonas aeruginosa infections are the primary cause of mortality in people with cystic fibrosis (CF). Yet, it has only recently become appreciated that resistance mutations can also increase P. aeruginosa virulence, even in t
Externí odkaz:
https://doaj.org/article/9ff32987f2ec4cb9a833b7485145f355
Autor:
Soban Umar, Gregoire Ruffenach, Shayan Moazeni, Mylene Vaillancourt, Jason Hong, Christine Cunningham, Nancy Cao, Sara Navab, Shervin Sarji, Min Li, Lisa Lee, Greg Fishbein, Abbas Ardehali, Mohamad Navab, Srinivasa T. Reddy, Mansoureh Eghbali
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 9, Iss 2 (2020)
Background Recently, we and others have reported a causal role for oxidized lipids in the pathogenesis of pulmonary hypertension (PH). However, the role of low‐density lipoprotein receptor (LDL‐R) in PH is not known. Methods and Results We examin
Externí odkaz:
https://doaj.org/article/20bedb735816416ebb5d93d9e3e491c4
Autor:
Mylene Vaillancourt, Pamela Chia, Lejla Medzikovic, Nancy Cao, Gregoire Ruffenach, David Younessi, Soban Umar
Publikováno v:
Frontiers in Physiology, Vol 10 (2019)
RationalePulmonary hypertension (PH) is a rare but fatal disease characterized by elevated pulmonary pressures and vascular remodeling, leading to right ventricular failure and death. Recently, neuroinflammation has been suggested to be involved in t
Externí odkaz:
https://doaj.org/article/b10b4a648b8a4f89b0c17a09b8650005