Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Mylène, Bohec"'
Autor:
Lara Al Zouabi, Marine Stefanutti, Spyridon Roumeliotis, Gwenn Le Meur, Benjamin Boumard, Nick Riddiford, Natalia Rubanova, Mylène Bohec, Louis Gervais, Nicolas Servant, Allison J. Bardin
Publikováno v:
Cell Reports, Vol 42, Iss 12, Pp 113485- (2023)
Summary: During development and aging, genome mutation leading to loss of heterozygosity (LOH) can uncover recessive phenotypes within tissue compartments. This phenomenon occurs in normal human tissues and is prevalent in pathological genetic condit
Externí odkaz:
https://doaj.org/article/bc7cd3a3c8c7477faf2b30300a471dba
Autor:
Stefano Gnan, Joseph M. Josephides, Xia Wu, Manuela Spagnuolo, Dalila Saulebekova, Mylène Bohec, Marie Dumont, Laura G. Baudrin, Daniele Fachinetti, Sylvain Baulande, Chun-Long Chen
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
A scalable approach to explore DNA replication in single cells reveals that although aneuploidy does not have a major impact on the pattern of replication, different cell types and sub-populations display distinguished replication paths.
Externí odkaz:
https://doaj.org/article/fd1aed25b9a042d2a333d9c51e20f10b
Autor:
Birgit Geoerger, Aurélien Marabelle, Gaelle Pierron, Nadege Gruel, Arnaud Gauthier, Olivier Delattre, Gudrun Schleiermacher, Ana Costa, Cécile Thirant, Amira Kramdi, Cécile Pierre-Eugène, Caroline Louis-Brennetot, Orphée Blanchard, Didier Surdez, Eve Lapouble, Deborah Sitbon, Hervé Brisse, Paul Fréneaux, Mylène Bohec, Virginie Raynal, Sylvain Baulande, Renaud Leclere, Gabriel Champenois, Andre Nicolas, Didier Meseure, Angela Bellini, Fatima Mechta-Grigoriou, Laurie Menger, Isabelle Janoueix-Lerosey
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 8 (2022)
Background High-risk neuroblastoma is a pediatric cancer with still a dismal prognosis, despite multimodal and intensive therapies. Tumor microenvironment represents a key component of the tumor ecosystem the complexity of which has to be accurately
Externí odkaz:
https://doaj.org/article/94bfccd475c140a08e383b0eb1c1e8c1
Autor:
Riccardo Gamba, Giulia Mazzucco, Therese Wilhelm, Leonid Velikovsky, Catalina Salinas-Luypaert, Florian Chardon, Julien Picotto, Mylène Bohec, Sylvain Baulande, Ylli Doksani, Daniele Fachinetti
Publikováno v:
PLoS Genetics, Vol 18, Iss 7 (2022)
Centromeres are key elements for chromosome segregation. Canonical centromeres are built over long-stretches of tandem repetitive arrays. Despite being quite abundant compared to other loci, centromere sequences overall still represent only 2 to 5% o
Externí odkaz:
https://doaj.org/article/272faa3ba4e54c9fb8d4d6d44646dd6b
Autor:
Elodie Montaudon, Joanna Nikitorowicz-Buniak, Laura Sourd, Ludivine Morisset, Rania El Botty, Léa Huguet, Ahmed Dahmani, Pierre Painsec, Fariba Nemati, Sophie Vacher, Walid Chemlali, Julien Masliah-Planchon, Sophie Château-Joubert, Camilla Rega, Mariana Ferreira Leal, Nikiana Simigdala, Sunil Pancholi, Ricardo Ribas, André Nicolas, Didier Meseure, Anne Vincent-Salomon, Cécile Reyes, Audrey Rapinat, David Gentien, Thibaut Larcher, Mylène Bohec, Sylvain Baulande, Virginie Bernard, Didier Decaudin, Florence Coussy, Muriel Le Romancer, Guillaume Dutertre, Zakia Tariq, Paul Cottu, Keltouma Driouch, Ivan Bièche, Lesley-Ann Martin, Elisabetta Marangoni
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
Identifying novel therapies for the treatment of CDK4/6 inhibitor-resistant patients is of great importance. Here, the authors demonstrate that PLK1 inhibition is a potential therapeutic target in CCND1-driven and in RB-positive Palbociclib-resistant
Externí odkaz:
https://doaj.org/article/cbbadef41cb14a1b91639138a1f60fcb
Autor:
Thibault Passeri, Tom Gutman, Abderaouf Hamza, Homa Adle-Biassette, Elodie Girard, Romane Beaurepere, Zakia Tariq, Odette Mariani, Ahmed Dahmani, Christine Bourneix, Rosaria Abbritti, Keltouma Driouch, Mylène Bohec, Nicolas Servant, Sylvain Baulande, Didier Decaudin, Jean-Pierre Guichard, Valentin Calugaru, Loïc Feuvret, Jean-Marc Guinebretière, Laurence Champion, Ivan Bièche, Sébastien Froelich, Hamid Mammar, Julien Masliah-Planchon
Publikováno v:
Journal of Neurosurgery. :1-11
OBJECTIVE Chordomas are rare bone neoplasms characterized by a high recurrence rate and no benefit from any approved medical treatment to date. However, the investigation of molecular alterations in chordomas could be essential to prognosticate, guid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::174c385950dae4b0a2ae9fb13563ff21
https://doi.org/10.3171/2023.1.jns222180
https://doi.org/10.3171/2023.1.jns222180
Autor:
Tsing-Lee Tang-Huau, Paul Gueguen, Christel Goudot, Mélanie Durand, Mylène Bohec, Sylvain Baulande, Benoit Pasquier, Sebastian Amigorena, Elodie Segura
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
Cross-presentation, or the presentation of exogenous antigens on MHC-I, is thought to be restricted to dendritic cells (DCs). Here the authors show that human DCs and macrophages developed in vivo from monocytes can both perform cross-presentation us
Externí odkaz:
https://doaj.org/article/fbdccbe896344f34ab585eae4a11785d
Autor:
Céline Chauvin, Amaury Leruste, Arnault Tauziede-Espariat, Mamy Andrianteranagna, Didier Surdez, Aurianne Lescure, Zhi-Yan Han, Elodie Anthony, Wilfrid Richer, Sylvain Baulande, Mylène Bohec, Sakina Zaidi, Marie-Ming Aynaud, Laetitia Maillot, Julien Masliah-Planchon, Stefano Cairo, Sergio Roman-Roman, Olivier Delattre, Elaine Del Nery, Franck Bourdeaut
Publikováno v:
Cell Reports, Vol 21, Iss 7, Pp 1737-1745 (2017)
Summary: Rhabdoid tumors (RTs) are aggressive tumors of early childhood characterized by SMARCB1 inactivation. Their poor prognosis highlights an urgent need to develop new therapies. Here, we performed a high-throughput screening of approved drugs a
Externí odkaz:
https://doaj.org/article/d423d349b9b14f909111a6ac8efab59a
Autor:
Andreea Calugareanu, Florian Specque, Sarah Demouche, Chloe Grolleau, Gabor Dobos, Marine Merandet, David Bergerat, Sandy Peltier, Marie Jachiet, Charles Cassius, Thibault Mahevas, Anne Saussine, Alexandre How-Kit, Rachel Onifarasoaniaina, Kevin Serror, Mylène Bohec, Sylvain Baulande, Clemence Lepelletier, Marc Mrad, Estelle Charvet, Adèle de Masson, David Boccara, Maxime Battistella, Hélène Le Buanec, Jean-David Bouaziz
Publikováno v:
Journal of Investigative Dermatology.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::15e88a5eac905b302772d77b7e3c3589
https://doi.org/10.1016/j.jid.2023.05.011
https://doi.org/10.1016/j.jid.2023.05.011
Autor:
Vincent Favaudon, Arturo Londoño-Vallejo, Marie Dutreix, Pierre Verrelle, Marc Vooijs, Sylvain Baulande, Mylène Bohec, Hamza Umut Karakurt, Sophie Leboucher, Arnaud Beddok, Sarah Bonnet-Boissinot, Sophie Heinrich, Eddy Quelennec, Lorena Giuranno, Sandra Curras-Alonso, Charles Fouillade
Purpose:One of the main limitations to anticancer radiotherapy lies in irreversible damage to healthy tissues located within the radiation field. “FLASH” irradiation at very high dose-rate is a new treatment modality that has been reported to spe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38ed6d7cae488680025a6bef70ead337
https://doi.org/10.1158/1078-0432.c.6528476
https://doi.org/10.1158/1078-0432.c.6528476
