Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Myeung Hoon Jo"'
Autor:
Tahir Ali, Shafiq Ur Rehman, Amjad Khan, Haroon Badshah, Noman Bin Abid, Min Woo Kim, Myeung Hoon Jo, Seung Soo Chung, Hyoung-gon Lee, Bart P. F. Rutten, Myeong Ok Kim
Publikováno v:
Molecular Neurodegeneration, Vol 16, Iss 1, Pp 1-22 (2021)
Abstract Background Recently, we and other researchers reported that brain metabolic disorders are implicated in Alzheimer’s disease (AD), a progressive, devastating and incurable neurodegenerative disease. Hence, novel therapeutic approaches are u
Externí odkaz:
https://doaj.org/article/54a9a1821f20455094f58251382be977
Autor:
Rahat Ullah, Myeung Hoon Jo, Muhammad Riaz, Sayed Ibrar Alam, Kamran Saeed, Waqar Ali, Inayat Ur Rehman, Muhammad Ikram, Myeong Ok Kim
Publikováno v:
Journal of Neuroinflammation, Vol 17, Iss 1, Pp 1-21 (2020)
Abstract Background Glycine is the smallest nonessential amino acid and has previously unrecognized neurotherapeutic effects. In this study, we examined the mechanism underlying the neuroprotective effect of glycine (Gly) against neuroapoptosis, neur
Externí odkaz:
https://doaj.org/article/e6ce7975f7a041caa1490042e9e2639e
Autor:
Sareer Ahmad, Amjad Khan, Waqar Ali, Myeung Hoon Jo, Junsung Park, Muhammad Ikram, Myeong Ok Kim
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Herein, we have evaluated the protective potentials of Fisetin against d-galactose-induced oxidative stress, neuroinflammation, and memory impairment in mice. d-galactose (D-gal) causes neurological impairment by inducing reactive oxygen species (ROS
Externí odkaz:
https://doaj.org/article/f65155b5d0534877a9eb22269708b9c8
Autor:
Jun Sung Park, Kamran Saeed, Myeung Hoon Jo, Min Woo Kim, Hyeon Jin Lee, Chan-Bae Park, Gwang Lee, Myeong Ok Kim
Publikováno v:
Antioxidants, Vol 11, Iss 2, p 261 (2022)
Age-related decline in mitochondrial function and oxidative stress plays a critical role in neurodegeneration. Lactate dehydrogenase-B (LDHB) is a glycolytic enzyme that catalyzes the conversion of lactate, an important brain energy substrate, into p
Externí odkaz:
https://doaj.org/article/4aca47cdc35241ca9e1f3dee70e48f19
Autor:
Muhammad Ikram, Myeung Hoon Jo, Kyonghwan Choe, Amjad Khan, Sareer Ahmad, Kamran Saeed, Min Woo Kim, Myeong Ok Kim
Publikováno v:
Cells, Vol 10, Iss 10, p 2719 (2021)
Here, we have unveiled the effects of cycloastragenol against Aβ (Amyloid-beta)-induced oxidative stress, neurogenic dysfunction, activated mitogen-activated protein (MAP) kinases, and mitochondrial apoptosis in an Aβ-induced mouse model of Alzheim
Externí odkaz:
https://doaj.org/article/51ff63acc5ba499eaebc094b9389e82a
Autor:
Kamran Saeed, Myeung Hoon Jo, Jun Sung Park, Sayed Ibrar Alam, Ibrahim Khan, Riaz Ahmad, Amjad Khan, Rahat Ullah, Myeong Ok Kim
Publikováno v:
Antioxidants, Vol 10, Iss 11, p 1682 (2021)
Disruptions in brain energy metabolism, oxidative damage, and neuroinflammation are commonly seen in traumatic brain injury (TBI). Microglial activation is the hallmark of neuroinflammation. After brain injury, microglia also act as a double-edged sw
Externí odkaz:
https://doaj.org/article/8a4d88c1ef274e13b47aefee47a464d7
Publikováno v:
Cells, Vol 9, Iss 1, p 249 (2020)
Oxidative stress and insulin resistance play major roles in numerous neurodegenerative diseases, including Alzheimer’s disease (AD). A high-fat diet induces obesity-associated oxidative stress, neuronal insulin resistance, microglial activation, an
Externí odkaz:
https://doaj.org/article/ca584e4054b248508c177f8e3a69e335
Autor:
Mehtab Khan, Rahat Ullah, Shafiq Ur Rehman, Shahid Ali Shah, Kamran Saeed, Tahir Muhammad, Hyun Young Park, Myeung Hoon Jo, Kyonghwan Choe, Bart P.F. Rutten, Myeong Ok Kim
Publikováno v:
Cells, Vol 8, Iss 8, p 928 (2019)
Oxidative stress has been considered the main mediator in neurodegenerative disease and in normal aging processes. Several studies have reported that the accumulation of reactive oxygen species (ROS), elevated oxidative stress, and neuroinflammation
Externí odkaz:
https://doaj.org/article/0299f64c49a54106955e9b2c8ee3a462
Autor:
Jun Sung Park, Kyonghwan Choe, Amjad Khan, Myeung Hoon Jo, Hyun Young Park, Min Hwa Kang, Tae Ju Park, Myeong Ok Kim
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 6; Pages: 5283
International Journal of Molecular Sciences, 24(6):5283. Multidisciplinary Digital Publishing Institute (MDPI)
International Journal of Molecular Sciences, 24(6):5283. Multidisciplinary Digital Publishing Institute (MDPI)
The blood–brain barrier (BBB) is a functional interface that provides selective permeability, protection from toxic substances, transport of nutrients, and clearance of brain metabolites. Additionally, BBB disruption has been shown to play a role i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9431cfdd74bc2a9ae3d5b31cf185f221
Autor:
Min Woo Kim, Tae Ju Park, Myeong Ok Kim, Muhammad Ikram, Min Gi Jo, Ibrahim Khan, Myeung Hoon Jo
Publikováno v:
Oxidative Medicine and Cellular Longevity, Vol 2021 (2021)
The study was aimed at analyzing the protective effects of gintonin in an amyloid beta- (Aβ-) induced Alzheimer’s disease (AD) mouse model. For the development of the Aβ-induced AD mouse model, the amyloid-β (Aβ1-42) peptide was stereotaxically
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d149aacb394596d5f1669c5326c9b5c2
https://doi.org/10.1155/2021/6635552
https://doi.org/10.1155/2021/6635552