Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Myer R, Salaman"'
Breakdown of T-cell ignorance: The tolerance failure responsible for mainstream autoimmune diseases?
Autor:
Myer R. Salaman, Keith G. Gould
Publikováno v:
Journal of Translational Autoimmunity, Vol 3, Iss , Pp 100070- (2020)
This article explores the possibility that the major autoimmune diseases come about because of the breakdown of T lymphocyte ignorance – that state in which antigen and lymphocyte have never come together in such a way as to induce tolerance or an
Externí odkaz:
https://doaj.org/article/b54497c5fd5e456aab6a99fe7e18fdb5
Autor:
Myer R. Salaman
Publikováno v:
Immunology Letters. 148:49-52
Whereas systemic lupus erythematosus (SLE) as normally encountered results from the coming together of a complex mix of genetic and environmental factors, SLE also develops in virtually all those rare people who lack a functional gene for the first c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0744aada1bd978d1224b886450be7b19
https://doi.org/10.1016/j.imlet.2012.07.004
https://doi.org/10.1016/j.imlet.2012.07.004
Autor:
M H Seifert, Maggie Larché, Myer R. Salaman, David A. Isenberg, Amy S. M. Kennell, Matthew R. J. Green
Publikováno v:
Arthritis & Rheumatism. 56:303-310
Objective To determine whether there is a link between the frequency of natural killer T (NKT) cells and high levels of IgG in patients with systemic lupus erythematosus (SLE) and their relatives. Methods Blood samples were obtained from patients wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9270bb47ba53fba22f6bdfbf4fb95543
https://doi.org/10.1002/art.22326
https://doi.org/10.1002/art.22326
Autor:
Jim Warwicker, Myer R. Salaman
Publikováno v:
Proteins: Structure, Function, and Bioinformatics. 61:468-472
The documented difference in the isoionic points of native and unfolded serum albumins is revisited with computational methods. Good agreement between calculated and measured ΔpIs is found, with the molecular origin appearing to reside in a diverse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0279a58143c399da8cf532163eec4ede
https://doi.org/10.1002/prot.20628
https://doi.org/10.1002/prot.20628
Publikováno v:
Clinical immunology (Orlando, Fla.). 157(2)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f2ca0aa8bb02a3f2b69e1c66e55be4b
https://pubmed.ncbi.nlm.nih.gov/25638415
https://pubmed.ncbi.nlm.nih.gov/25638415
Publikováno v:
BMC Research Notes
Background It can be difficult to register a weak proliferative response of T lymphocytes to an antigen, particularly in a simple culture system of peripheral blood mononuclear cells (PBMC). Here we assess the usefulness of the cytokine IL-2 in ampli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b33cf3e8eae909dedc77ac89fff55446
https://pubmed.ncbi.nlm.nih.gov/25239080
https://pubmed.ncbi.nlm.nih.gov/25239080
Publikováno v:
Lupus. 10:332-339
Blood mononuclear cells from 20 lupus patients were cultured in the presence of nucleosomal antigens to determine whether they induce lymphocyte proliferation. The predominant effect seen, however, was one of inhibition of the background proliferatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::311228d117a6548cba7f8b94d73080b9
https://doi.org/10.1191/096120301678064089
https://doi.org/10.1191/096120301678064089
Autor:
Myer R. Salaman
Publikováno v:
Tuberculosis (Edinburgh, Scotland). 93(6)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3af581d885ca4591ef5d28bed2fbc69f
https://pubmed.ncbi.nlm.nih.gov/24074512
https://pubmed.ncbi.nlm.nih.gov/24074512
Publikováno v:
International Journal of Immunopharmacology. 15:287-291
Studies are reported on the inhibition of DNA synthesis and the lowering of cell viability caused by bis(tributyltin) oxide in mouse spleen cells cultured in the presence and absence of the B-lymphocyte mitogen, bacterial lipopolysaccharide. When a m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::761d66bda118a3e14df42f6b2c125597
https://doi.org/10.1016/0192-0561(93)90038-z
https://doi.org/10.1016/0192-0561(93)90038-z
Autor:
M. R. J. Green, Amy S. M. Kennell, M H Seifert, David A. Isenberg, Maggie Larché, Myer R. Salaman
Publikováno v:
Clinical and experimental immunology. 157(1)
Summary A well-recognized characteristic of the autoimmune disease, systemic lupus erythematosus (SLE), is the high level of activated T cells present in the blood. Because of the increased size and granularity of activated T cells, in flow cytometry
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01e4aad2091eb171c2c1717d6b78c704
https://pubmed.ncbi.nlm.nih.gov/19659768
https://pubmed.ncbi.nlm.nih.gov/19659768