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pro vyhledávání: '"Myer R"'
Breakdown of T-cell ignorance: The tolerance failure responsible for mainstream autoimmune diseases?
Autor:
Myer R. Salaman, Keith G. Gould
Publikováno v:
Journal of Translational Autoimmunity, Vol 3, Iss , Pp 100070- (2020)
This article explores the possibility that the major autoimmune diseases come about because of the breakdown of T lymphocyte ignorance – that state in which antigen and lymphocyte have never come together in such a way as to induce tolerance or an
Externí odkaz:
https://doaj.org/article/b54497c5fd5e456aab6a99fe7e18fdb5
Akademický článek
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Autor:
Salaman, Myer R.1
Publikováno v:
Autoimmunity. Mar2003, Vol. 36 Issue 2, p57. 5p.
Autor:
Myer R. Salaman
Publikováno v:
Immunology Letters. 148:49-52
Whereas systemic lupus erythematosus (SLE) as normally encountered results from the coming together of a complex mix of genetic and environmental factors, SLE also develops in virtually all those rare people who lack a functional gene for the first c
Autor:
M H Seifert, Maggie Larché, Myer R. Salaman, David A. Isenberg, Amy S. M. Kennell, Matthew R. J. Green
Publikováno v:
Arthritis & Rheumatism. 56:303-310
Objective To determine whether there is a link between the frequency of natural killer T (NKT) cells and high levels of IgG in patients with systemic lupus erythematosus (SLE) and their relatives. Methods Blood samples were obtained from patients wit
Autor:
Jim Warwicker, Myer R. Salaman
Publikováno v:
Proteins: Structure, Function, and Bioinformatics. 61:468-472
The documented difference in the isoionic points of native and unfolded serum albumins is revisited with computational methods. Good agreement between calculated and measured ΔpIs is found, with the molecular origin appearing to reside in a diverse
Autor:
Sager, Alan, Socolar, Deborah, Dent III, Fred, Hummel, William, Hutchinson, Don, Opdyke, Wanda, Myer, R. J., Georgakopoulos, Nicholas, O'Brien, John Michael, Fuller, Craig L., Levin, Michael D., Stern, Louis W., Bell, Steven J., Gardner, Walt
Publikováno v:
BusinessWeek; 12/31/2001, Issue 3764, p16-24, 4p
Publikováno v:
Clinical immunology (Orlando, Fla.). 157(2)
Publikováno v:
BMC Research Notes
Background It can be difficult to register a weak proliferative response of T lymphocytes to an antigen, particularly in a simple culture system of peripheral blood mononuclear cells (PBMC). Here we assess the usefulness of the cytokine IL-2 in ampli
Publikováno v:
Lupus. 10:332-339
Blood mononuclear cells from 20 lupus patients were cultured in the presence of nucleosomal antigens to determine whether they induce lymphocyte proliferation. The predominant effect seen, however, was one of inhibition of the background proliferatio