Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Myeongjin Yi"'
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2418
Estrogen receptor α (ERα) conserves a phosphorylation motif at Serine 216. This site constitutes a protein kinase C phosphorylation motif located within the DNA binding domain (DBD) of ERα. The liver plays a critical role in the regulation of meta
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2418
Serine 216 constitutes a protein kinase C phosphorylation motif located within the DNA binding domain of estrogen receptor α (ERα). In this chapter, we present experimental procedures confirming that mouse ERα is phosphorylated at serine 216 in pe
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020)
Scientific Reports
Scientific Reports
Estrogen sulfotransferase (SULT1E1) inactivates estrogen and regulates its metabolic homeostats. Whereas SULT1E1 is expressed low in the liver of adult mice, it is induced by phenobarbital (PB) treatment or spontaneously in diabetic livers via nuclea
Publikováno v:
Methods in Molecular Biology ISBN: 9781071619193
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3b36592e385c0726e65ed56b07936c42
https://doi.org/10.1007/978-1-0716-1920-9_3
https://doi.org/10.1007/978-1-0716-1920-9_3
Publikováno v:
Methods in Molecular Biology ISBN: 9781071619193
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cfb5cefd560ad137f827c80bf1004f19
https://doi.org/10.1007/978-1-0716-1920-9_5
https://doi.org/10.1007/978-1-0716-1920-9_5
Autor:
Rong Li, Tian-yuan Wang, Xin Xu, Olivia M Emery, MyeongJin Yi, San-Pin Wu, Francesco J DeMayo
Publikováno v:
Biol Reprod
Uterine dysfunctions lead to fertility disorders and pregnancy complications. Normal uterine functions at pregnancy depend on crosstalk among multiple cell types in uterine microenvironments. Here, we performed the spatial transcriptomics and single-
Autor:
Sang Seop Lee, Su-Jun Lee, Sun-Ah Cho, Sung-Eun Yoo, Woo-Young Kim, Myeongjin Yi, Jae-Gook Shin
Publikováno v:
Drug Metabolism and Pharmacokinetics. 34:201-208
The objective of the present study was to investigate the effects of cytochrome b5 (cytb5) on the drug metabolism catalyzed by CYP2C9, CYP2C19 and CYP3A4. Activities of CYP2C9, CYP2C19, and CYP3A4 were determined by using the prototypical substrates
Publikováno v:
Biochem Pharmacol
Circulating estrogens levels significantly decrease in menopause and levels off in postmenopausal women. Accordingly, the liver represses levels of enzymes and membrane transporters, thereby decreasing capability of inactivating and excreting estroge
Publikováno v:
Ann Hum Genet
Phosphodiesterase 3A (PDE3A) is an enzyme that plays an important role in the regulation of cyclic adenosine monophosphate (cAMP)-mediated intracellular signaling in cardiac myocytes and platelets. PDE3A hydrolyzes cAMP, which results in a decrease i
Publikováno v:
FEBS Letters. 592:2760-2768
The estrogen sulfotransferase SULT1E1 sulfates and inactivates estrogen, which is reactivated via desulfation by steroid sulfatase, thus regulating estrogen homeostasis. Phenobarbital (PB), a clinical sedative, activates Sult1e1 gene transcription in