Zobrazeno 1 - 2
of 2
pro vyhledávání: '"MyeongJae Cheon"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract In recent years, the utility of polygenic risk scores (PRS) in forecasting disease susceptibility from genome-wide association studies (GWAS) results has been widely recognised. Yet, these models face limitations due to overfitting and the p
Externí odkaz:
https://doaj.org/article/cae0d85eb66646f4a738e90a5681af75
In this study, we developed a deep neural network (DNN) model with weight correlation descent (WCD) regularization to improve polygenic risk score predictions for complex diseases, specifically gender-specific cancers, using the UK Biobank dataset. O
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fff6c325f6c52cf752f29a5e3af3e260
https://doi.org/10.1101/2023.05.23.23290438
https://doi.org/10.1101/2023.05.23.23290438
