Zobrazeno 1 - 10
of 184
pro vyhledávání: '"Myeong-Sok Lee"'
Autor:
Shangyong Li, Hui Zhang, Kaiwei Chen, Mengfei Jin, Son Hai Vu, Samil Jung, Ningning He, Zhou Zheng, Myeong-Sok Lee
Publikováno v:
Drug Delivery, Vol 29, Iss 1, Pp 1142-1149 (2022)
Oral drug delivery systems (ODDSs) have various advantages of simple operation and few side effects. ODDSs are highly desirable for colon-targeted therapy (e.g. ulcerative colitis and colorectal cancer), as they improve therapeutic efficiency and red
Externí odkaz:
https://doaj.org/article/62867b5d8ee242df8832772075417a86
Autor:
Jin Gu Cho, Sung-wook Kim, Aram Lee, Ha-neul Jeong, Eunsik Yun, Jihea Choi, Su Jin Jeong, Woochul Chang, Sumin Oh, Kyung Hyun Yoo, Jung Bok Lee, Sukjoon Yoon, Myeong-Sok Lee, Jong Hoon Park, Min Hyung Jung, So-Woon Kim, Ki Hyung Kim, Dong Soo Suh, Kyung Un Choi, Jungmin Choi, Jongmin Kim, Byung Su Kwon
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 29, Iss , Pp 803-822 (2022)
Cancer stem-like cells (CSCs) have been suggested to be responsible for chemoresistance and tumor recurrence owing to their self-renewal capacity and differentiation potential. Although WEE1 is a strong candidate target for anticancer therapies, its
Externí odkaz:
https://doaj.org/article/2292e1739f1e48f0a24e453d19fda611
Autor:
Thi Ngoc Quynh Nguyen, Samil Jung, Hai Anh Nguyen, BeomSuk Lee, Son Hai Vu, Davaajargal Myagmarjav, Hye Hyeon Eum, Hae-Ock Lee, Taeyeon Jo, Yeongseon Choi, Myeong-Sok Lee
Publikováno v:
Journal of Hematology & Oncology, Vol 15, Iss 1, Pp 1-5 (2022)
Abstract Much higher risk of cancer has been found in diabetes patients. Insulin receptor (IR) and insulin-like growth factor 1 receptor (IGF1R) have been extensively studied in both breast cancer and diabetes therapies. Interestingly, a recent study
Externí odkaz:
https://doaj.org/article/2b17075836234c55805ee976b62166ce
Autor:
Niranjan Kumar, Rakesh Srivastava, Raj Kumar Mongre, Chandra Bhushan Mishra, Amit Kumar, Rosy Khatoon, Atanu Banerjee, Md Ashraf-Uz-Zaman, Harpreet Singh, Andrew M. Lynn, Myeong-Sok Lee, Amresh Prakash
Publikováno v:
Frontiers in Microbiology, Vol 13 (2022)
Mycolic acids are the key constituents of mycobacterial cell wall, which protect the bacteria from antibiotic susceptibility, helping to subvert and escape from the host immune system. Thus, the enzymes involved in regulating and biosynthesis of myco
Externí odkaz:
https://doaj.org/article/60ba41a1cebf4db481344a1686ad980b
Autor:
Chandra Bhushan Mishra, Raj Kumar Mongre, Amresh Prakash, Raok Jeon, Claudiu T. Supuran, Myeong-Sok Lee
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 36, Iss 1, Pp 954-963 (2021)
Anti-breast cancer action of novel human carbonic anhydrase IX (hCA IX) inhibitor BSM-0004 has been investigated using in vitro and in vivo models of breast cancer. BSM-0004 was found to be a potent and selective hCA IX inhibitor with a Ki value of 9
Externí odkaz:
https://doaj.org/article/87f0a18287ba459e93ce4b46f9862161
Publikováno v:
Drug Delivery, Vol 28, Iss 1, Pp 1120-1131 (2021)
Oral route colon-targeted drug delivery systems (CDDSs) are desirable for the treatment of ulcerative colitis (UC). However, CDDSs are challenging owing to the physiological and anatomical barriers associated with the gastrointestinal tract (GIT). In
Externí odkaz:
https://doaj.org/article/cacf7fc8d2144755b31b8d0779f52ce7
Autor:
Raj Kumar Mongre, Chandra Bhushan Mishra, Samil Jung, Beom Suk Lee, Nguyen Thi Ngoc Quynh, Nguyen Hai Anh, Davaajragal Myagmarjav, Taeyeon Jo, Myeong-Sok Lee
Publikováno v:
Molecular Therapy: Oncolytics, Vol 19, Iss , Pp 105-126 (2020)
TRIP-Brs, a group of transcription factors (TFs) that modulate several mechanisms in higher organisms. However, the novel paradigm to target TRIP-Brs in specific cancer remains to be deciphered. In particular, comprehensive analysis of TRIP-Brs in cl
Externí odkaz:
https://doaj.org/article/56061782e6e341898450d482f68d56ae
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 18, p 10906 (2022)
Cancer immunotherapy has fundamentally altered cancer treatment; however, its efficacy is limited to a subset of patients in most clinical settings. The immune system plays a key role in cancer progression from tumor initiation to the metastatic stat
Externí odkaz:
https://doaj.org/article/3693bff5c7b742f0bb6fe3bec4f43299
Autor:
Hai Anh Nguyen, Son Hai Vu, Samil Jung, Beom Suk Lee, Thi Ngoc Quynh Nguyen, Hyojeong Lee, Hye-gyeong Lee, Davaajargal Myagmarjav, Taeyeon Jo, Yeongseon Choi, Myeong-Sok Lee
Publikováno v:
Biomedicines, Vol 10, Iss 5, p 1148 (2022)
Acquired chemoresistance of tumor cells is an unwanted consequence of cancer treatment. Overcoming chemoresistance is particularly important for efficiently improving cancer therapies. Here, using multiple lines of evidence, we report the suppressive
Externí odkaz:
https://doaj.org/article/b6fe3f1abd774183874cb5fc1da23635
Publikováno v:
Cancers, Vol 13, Iss 23, p 6112 (2021)
(1) Background: The aim of the present study was to evaluate the effect of NDRG2 expression in regulating PD-L1 or PD-L2 on malignant breast cancer cells. (2) Methods: Overexpression and knockdown of the NDRG2 gene in human and mouse cancer cells wer
Externí odkaz:
https://doaj.org/article/500aa85515ed431f96eaf2b32cefd0c7