Zobrazeno 1 - 10
of 89
pro vyhledávání: '"Myeong-Sang Yu"'
Autor:
Daeahn Cho, Myeong-Sang Yu, Jeongyoon Shin, Jingyu Lee, Yubin Kim, Hoon-Chul Kang, Se Hee Kim, Dokyun Na
Publikováno v:
BMC Medical Informatics and Decision Making, Vol 24, Iss S2, Pp 1-9 (2024)
Abstract Background Epilepsy, a chronic brain disorder characterized by abnormal brain activity that causes seizures and other symptoms, is typically treated using anti-epileptic drugs (AEDs) as the first-line therapy. However, due to the variations
Externí odkaz:
https://doaj.org/article/46bc8951cf4c4a839acfdfc13e3e88e4
Autor:
Dokyun Na, Do‐Hwan Lim, Jae‐Sang Hong, Hyang‐Mi Lee, Daeahn Cho, Myeong‐Sang Yu, Bilal Shaker, Jun Ren, Bomi Lee, Jae Gwang Song, Yuna Oh, Kyungeun Lee, Kwang‐Seok Oh, Mi Young Lee, Min‐Seok Choi, Han Saem Choi, Yang‐Hee Kim, Jennifer M Bui, Kangseok Lee, Hyung Wook Kim, Young Sik Lee, Jörg Gsponer
Publikováno v:
Molecular Systems Biology, Vol 19, Iss 12, Pp n/a-n/a (2023)
Abstract The accumulation of misfolded and aggregated proteins is a hallmark of neurodegenerative proteinopathies. Although multiple genetic loci have been associated with specific neurodegenerative diseases (NDs), molecular mechanisms that may have
Externí odkaz:
https://doaj.org/article/189ad69333ab48fca215c7cdd4f22dce
Autor:
Jae Gwang Song, Myeong-Sang Yu, Bomi Lee, Jingyu Lee, Su-Hee Hwang, Dokyun Na, Hyung Wook Kim
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 20, Iss , Pp 1097-1110 (2022)
For a long time, the central nervous system was believed to be the only regulator of cognitive functions. However, accumulating evidence suggests that the composition of the microbiome is strongly associated with brain functions and diseases. Indeed,
Externí odkaz:
https://doaj.org/article/e7b69bb8f1cf40c3a80ca49fbdc547fd
Autor:
Hyang-Mi Lee, Jun Ren, Myeong-Sang Yu, Hyunjoo Kim, Woo Young Kim, Junhao Shen, Seung Min Yoo, Seong-il Eyun, Dokyun Na
Publikováno v:
Biotechnology for Biofuels, Vol 14, Iss 1, Pp 1-12 (2021)
Abstract Background As methane is 84 times more potent than carbon dioxide in exacerbating the greenhouse effect, there is an increasing interest in the utilization of methanotrophic bacteria that can convert harmful methane into various value-added
Externí odkaz:
https://doaj.org/article/483c0706133f4ef6885765b9040a9b44
2-D chemical structure image-based in silico model to predict agonist activity for androgen receptor
Publikováno v:
BMC Bioinformatics, Vol 21, Iss S5, Pp 1-8 (2020)
Abstract Background Abnormal activation of human nuclear hormone receptors disrupts endocrine systems and thereby affects human health. There have been machine learning-based models to predict androgen receptor agonist activity. However, the models w
Externí odkaz:
https://doaj.org/article/defe9ac2b32f4097869c46aa67d80035
Autor:
Hyang-Mi Lee, Myeong-Sang Yu, Sayada Reemsha Kazmi, Seong Yun Oh, Ki-Hyeong Rhee, Myung-Ae Bae, Byung Ho Lee, Dae-Seop Shin, Kwang-Seok Oh, Hyithaek Ceong, Donghyun Lee, Dokyun Na
Publikováno v:
BMC Bioinformatics, Vol 20, Iss S10, Pp 67-73 (2019)
Abstract Background Drug candidates often cause an unwanted blockage of the potassium ion channel of the human ether-a-go-go-related gene (hERG). The blockage leads to long QT syndrome (LQTS), which is a severe life-threatening cardiac side effect. T
Externí odkaz:
https://doaj.org/article/21b68636ce9040cdb5dcd05e1187d818
Autor:
Myeong-Sang Yu, Hyang-Mi Lee, Aaron Park, Chungoo Park, Hyithaek Ceong, Ki-Hyeong Rhee, Dokyun Na
Publikováno v:
BMC Bioinformatics, Vol 19, Iss S8, Pp 29-37 (2018)
Abstract Background Administered drugs are often converted into an ineffective or activated form by enzymes in our body. Conventional in silico prediction approaches focused on therapeutically important enzymes such as CYP450. However, there are more
Externí odkaz:
https://doaj.org/article/2ecd5e28be3d4788ac084ecb01720b90
Autor:
Won Ung Park, Gyu-Bum Yeon, Myeong-Sang Yu, Hui-Gwan Goo, Su-Hee Hwang, Dokyun Na, Dae-Sung Kim
Publikováno v:
Biology, Vol 10, Iss 12, p 1254 (2021)
Differentiation of oligodendrocytes (ODs) presents a challenge in regenerative medicine due to their role in various neurological diseases associated with dysmyelination and demyelination. Here, we designed a peptide derived from vitronectin (VN) usi
Externí odkaz:
https://doaj.org/article/df838b9ed5bc42efa080c52534380655
Publikováno v:
Journal of Rhinology, Vol 30, Iss 2, Pp 115-119 (2023)
Although iatrogenic skull base injuries after endoscopic sinus surgery (ESS) are rare (overall complication rate, 0.5%), they can be fatal or cause significant morbidity. Conventionally, skull base injuries were repaired using an external approach. H
Externí odkaz:
https://doaj.org/article/76750b586fa94e1eb7a1087ea8c3a95b
Autor:
Shin Hyuk Yoo1, Myeong Sang Yu2 hiyums@hanmail.net
Publikováno v:
Journal of Rhinology. Nov2023, Vol. 30 Issue 3, p144-148. 5p.