Oxidative stress in the testis induced by tamoxifen and its effects on early embryo development in isogenic mice.

Autor: Sunghak Lee¹, Myeong-Seop Lee², Joonghoon Park³, Jin Yu Zhang¹, Dong Il Jin¹ dijin@cnu.ac.kr

Publikováno v: Journal of Toxicological Sciences. Aug2012, Vol. 37 Issue 4, p675-679. 5p.

Metformin enhances the action of insulin on porcine granulosa-lutein cells in vitro

Autor: Myeong Seop Lee, Sang Hwan Kim, Dae-Seung Kim, Kwan Sik Min, Jong Taek Yoon

Publikováno v: Animal Reproduction Science. 136:100-107

Metformin is an oral antidiabetic drug extensively used to treat the polycystic ovary syndrome in women. Metformin increases insulin-stimulated glucose uptake and has direct effects on ovarian steroidogenesis in humans. However, the molecular mechani

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::791a65972363aa09fb897e9c5239c83a
https://doi.org/10.1016/j.anireprosci.2012.10.001

Oxidative stress in the testis induced by tamoxifen and its effects on early embryo development in isogenic mice

Autor: Jin Yu Zhang, Myeong-Seop Lee, Sung Hak Lee, Joonghoon Park, Dong Il Jin

Publikováno v: The Journal of Toxicological Sciences. 37:675-679

Oxidative stress induced by tamoxifen (TAM) in male testis and its effects on fertility and early embryo development were investigated. TAM was orally administered for 4 weeks repeatedly to two isogenic male mice strains, inbred strain of C57BL/6J (B

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a8a4be408d8ca223332475727dbb7c4
https://doi.org/10.2131/jts.37.675

Development of a type II diabetic mellitus animal model using Micropig®

Autor: Myeong Seop Lee, Ki-Duk Song, Chester D Solis, Woon Kyu Lee, Hee Jun Yang, Soo Hyeon Kim

Publikováno v: Laboratory Animal Research

Diabetes, which has shown an explosive increase in terms of its incidence, is regarded as a serious disease that must be overcome for the sake of human life. Among animal models used for testing of drug efficacy, the mini-pig model has shown a rapid

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b422bf43bd06341d2c36c8290a8285c1
https://pubmed.ncbi.nlm.nih.gov/23091521

Human endometrial cell coculture reduces the endocrine disruptor toxicity on mouse embryo development

Autor: Myeong-Seop Lee, Ho-Yeon Song, Hae-Hyeog Lee, Young-Sang Lee

Publikováno v: Journal of Occupational Medicine and Toxicology (London, England)
Journal of Occupational Medicine and Toxicology, Vol 7, Iss 1, p 7 (2012)

Backgrounds Previous studies suggested that endocrine disruptors (ED) are toxic on preimplantation embryos and inhibit development of embryos in vitro culture. However, information about the toxicity of endocrine disruptors on preimplantation develop

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57e3363c8d1b02625aa2c93a7de3e1e5
http://europepmc.org/articles/PMC3480945