Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Myeong Heui Kim"'
Autor:
Il Bin Kim, Myeong-Heui Kim, Saehoon Jung, Woo Kyeong Kim, Junehawk Lee, Young Seok Ju, Maree J. Webster, Sanghyeon Kim, Ja Hye Kim, Hyun Jung Kim, Junho Kim, Sangwoo Kim, Jeong Ho Lee
Publikováno v:
Experimental and Molecular Medicine, Vol 56, Iss 8, Pp 1750-1762 (2024)
Abstract Low-level somatic mutations in the human brain are implicated in various neurological disorders. The contribution of low-level brain somatic mutations to autism spectrum disorder (ASD), however, remains poorly understood. Here, we performed
Externí odkaz:
https://doaj.org/article/0d5d2a61a356424e91f19af0456c7a2f
Autor:
Ja Hye Kim, Shinwon Hwang, Hyeonju Son, Dongsun Kim, Il Bin Kim, Myeong-Heui Kim, Nam Suk Sim, Dong Seok Kim, Yoo-Jin Ha, Junehawk Lee, Hoon-Chul Kang, Jeong Ho Lee, Sangwoo Kim
Publikováno v:
PLoS Genetics, Vol 18, Iss 9, p e1010404 (2022)
Most somatic mutations that arise during normal development are present at low levels in single or multiple tissues depending on the developmental stage and affected organs. However, the effect of human developmental stages or mutations of different
Externí odkaz:
https://doaj.org/article/8adbe6b857864a21b9f02a86744335c8
Autor:
Jun Sung Park, Junehawk Lee, Eun Sun Jung, Myeong-Heui Kim, Il Bin Kim, Hyeonju Son, Sangwoo Kim, Sanghyeon Kim, Young Mok Park, Inhee Mook-Jung, Seok Jong Yu, Jeong Ho Lee
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
The role of brain somatic mutations in neurodegenerative diseases such as Alzheimer’s disease (AD) is not well understood. Here the authors carry out high-depth exome sequencing ~500× on brain tissue from patients with AD and controls, and identif
Externí odkaz:
https://doaj.org/article/b694e92a879449b6991c1d1dd1d2b943
Autor:
Hyun Jung Kim, Do Hyeon Cha, Keon Woo Kim, Myeong Heui Kim, Jung Won Park, Jeong Ho Lee, Seok-gu Kang
Publikováno v:
WFNOS 2022 Abstract Book.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::af79d886d6846c179cad8d5e29423768
https://doi.org/10.14791/btrt.2022.10.f-2745
https://doi.org/10.14791/btrt.2022.10.f-2745
Autor:
Hyun Jung Kim, Do Hyeon Cha, Keon Woo Kim, Myeong Heui Kim, Jung Won Park, Ja Hye Kim, Seon Jin Yoon, Seok-Gu Kang, Jeong Ho Lee
Publikováno v:
Neuro-Oncology. 24:vii122-vii122
Glioblastoma (GBM) is the most common and aggressive primary brain cancer in adults. Although multiple oncogenic mutations have been identified in neural stem cells of the subventricular zone (SVZ) in humans, the dynamic process of how tumor initiati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8db528e77b14989f77d9f1f911d2c75c
https://doi.org/10.1093/neuonc/noac209.464
https://doi.org/10.1093/neuonc/noac209.464
Autor:
Sangwoo Kim, Ja Hye Kim, Nam Suk Sim, Jeong Ho Lee, Hyeonju Son, Dong Seok Kim, Il Bin Kim, Myeong-Heui Kim, Junehawk Lee
Most somatic mutations arising during normal development present as low-level in single or multiple tissues depending on the developmental stage and affected organs1-4. However, it remains unclear how the human developmental stages or mutation-carryi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::53db9fb28b7ea09fb29886cf8ead3f6a
https://doi.org/10.1101/2021.08.23.457440
https://doi.org/10.1101/2021.08.23.457440
Autor:
Hyeonju Son, Sangwoo Kim, Il Bin Kim, Inhee Mook-Jung, Jun Sung Park, Sanghyeon Kim, Eun Sun Jung, Seok Jong Yu, Jeong Ho Lee, Junehawk Lee, Young Mok Park, Myeong Heui Kim
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
Nature Communications
Nature Communications
The role of brain somatic mutations in Alzheimer’s disease (AD) is not well understood. Here, we perform deep whole-exome sequencing (average read depth 584×) in 111 postmortem hippocampal formation and matched blood samples from 52 patients with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0d11c4e909fe56cf8cf1e94f2207c60
http://link.springer.com/article/10.1038/s41467-019-11000-7
http://link.springer.com/article/10.1038/s41467-019-11000-7
Autor:
Il Bin Kim, Sang Min Park, Yohan An, Maree J. Webster, Jeong Ho Lee, Kyungdeok Kim, Do Hyeon Cha, Sanghyeon Kim, Jun Sung Park, Ja Hye Kim, Myeong-Heui Kim, Seyeon Kim, Junehawk Lee, Ryunhee Kim
Publikováno v:
Biological psychiatry. 90(1)
Background Somatic mutations arising from the brain have recently emerged as significant contributors to neurodevelopmental disorders, including childhood intractable epilepsy and cortical malformations. However, whether brain somatic mutations are i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e75f210b045e9b8d7c1c683355d4be3e
https://pubmed.ncbi.nlm.nih.gov/34140120
https://pubmed.ncbi.nlm.nih.gov/34140120
Autor:
Se-Young Choi, Dong Soo Lee, Myeong Heui Kim, Su Yeon Choi, Jaewon Ko, Yi Sul Cho, Tae-Yong Choi, Yong Chul Bae, Seojung Mo, Tyler Cutforth, Yeunkum Lee, Kihoon Han, Hyun Kim, Junyeop Daniel Roh, Eunjoon Kim, Jeong-Seop Rhee, Woosuk Chung, Hanwool Park, Jong Sil Park, Kang Shen
Publikováno v:
Frontiers in Molecular Neuroscience
Copy number variants and point mutations of NEPH2 (also called KIRREL3) gene encoding an immunoglobulin (Ig) superfamily adhesion molecule have been linked to autism spectrum disorders, intellectual disability and neurocognitive delay associated with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f13795e83e6af73fe92b44c0327be71
Autor:
Roh, Junyeop D., Su-Yeon Choi, Yi Sul Cho, Tae-Yong Choi, Jong-Sil Park, Cutforth, Tyler, Woosuk Chung, Hanwool Park, Dongsoo Lee, Myeong-Heui Kim, Yeunkum Lee, Seojung Mo, Jeong-Seop Rhee, Hyun Kim, Jaewon Ko, Se-Young Choi, Yong Chul Bae, Kang Shen, Eunjoon Kim, Kihoon Han
Publikováno v:
Frontiers in Molecular Neuroscience; 3/22/2017, Vol. 10, p1-11, 11p