Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Myeon-Woo Chung"'
Autor:
Hye-Jun Shin, Young Min Cho, Hee Jung Shin, Hae Deun Kim, Kyung Min Choi, Mi Gyeong Kim, Hyoung Doo Shin, Myeon-Woo Chung
Publikováno v:
Laboratory Animal Research, Vol 33, Iss 1, Pp 8-14 (2017)
Abstract Mouse is a commonly used animal in life science studies and is classified as outbred if genetically diverse and inbred if genetically homogeneous. Outbred mouse stocks, are used in toxicology, oncology, infection and pharmacology research. T
Externí odkaz:
https://doaj.org/article/baf494f3bffa4e8f9022b1bd298cfaee
Autor:
Boyoon Choi, Ki Yon Rhew, Therasa Kim, Jung Mi Oh, Han-Sung Na, In-Wha Kim, Myeon-Woo Chung, Eunhee Ji, Hyunah Kim, Yun-Kyoung Song, Minji Sohn, Nayoung Han, Sohyun Jeong
Publikováno v:
Int. Journal of Clinical Pharmacology and Therapeutics. 54:416-425
Objectives To construct a database of published clinical drug trials suitable for use 1) as a research tool in accessing clinical trial information and 2) in evidence-based decision-making by regulatory professionals, clinical research investigators,
Autor:
Tae Sun Kang, Hyoung Doo Shin, Hyun Sub Cheong, Myeon Woo Chung, Hyun Joo Park, Hee Jung Shin, Han Sung Na, Jin Sol Lee
Publikováno v:
Genes & Genetic Systems. 91:277-281
Since NAT2 single-nucleotide polymorphisms (SNPs) are responsible for the efficacy of arylamines and hydrazine drugs, defining the effects of these SNPs in various ethnicities is an important factor in the development of personalized medicine. In the
Autor:
Woojae Myung, Shinn Won Lim, Hye In Woo, Myeon Woo Chung, Doh Kwan Kim, Jung-Ryul Kim, Hae Deun Kim, Han Sung Na, Soo-Youn Lee, Mi Ryung Chun
Publikováno v:
Drug Design, Development and Therapy
Jung-Ryul Kim,1 Hye In Woo,2 Mi-Ryung Chun,3 Shinn-Won Lim,4 Hae Deun Kim,5 Han Sung Na,5 Myeon Woo Chung,5 Woojae Myung,6 Soo-Youn Lee,1,3 Doh Kwan Kim6 1Department of Clinical Pharmacology and Therapeutics, Samsung Medical Center, Seoul, 2Departmen
Autor:
Hyun Sub Cheong, Myeon Woo Chung, Hee Jung Shin, Jason Yongha Kim, Hyoung Doo Shin, Han Sung Na
Publikováno v:
Therapeutic Drug Monitoring. 37:369-374
Uridine diphosphate glucuronyltransferase 1 family, A1 (UGT1A1) encodes for an enzyme that is a part of glucuronidation pathway, and a number of studies have shown that the promoter polymorphisms of UGT1A1 are associated with various diseases and dru
Autor:
Joong-Gon Shin, Han Sung Na, Hyun Joo Park, Tae Sun Kang, Hyun Sub Cheong, Myeon Woo Chung, Hyoung Doo Shin, Hee Jung Shin
Publikováno v:
Therapeutic Drug Monitoring. 37:147-151
Dihydropyrimidine dehydrogenase (DPYD) is an enzyme that regulates the rate-limiting step in pyrimidine metabolism, especially catabolism of fluorouracil. This study was performed to analyze the association between DPYD genetic variants and DPYD enzy
Autor:
Jong Y. Park, Minju Kim, Mihi Yang, Soo Young Kim, Myeon Woo Chung, Hyun-Kyung Na, Seong-Sil Chang
Publikováno v:
Toxicology Letters. 232:429-437
Tobacco smoking is a well-known cause of various diseases, however, its toxic mechanisms for diseases are not completely understood, yet. Therefore, we performed biological monitoring to find tobacco smoking-responsive mechanisms including oxidative
Autor:
Myeon Woo Chung, Han Sung Na, Hyoung Doo Shin, Hyun Sub Cheong, Hee Jung Shin, Lyoung Hyo Kim, Jeong Hyun Kim
Publikováno v:
Genes & Genomics. 37:247-255
Low density lipoprotein receptor (LDLR) plays an important role in plasma lipoprotein metabolism and pharmacological responses. Although mutations of LDLR and their functional associations with plasma LDL cholesterol concentrations have been describe
Autor:
Hae Deun Kim, Myeon-Woo Chung, Hee Jung Shin, Jin-Ho Kim, Young Min Cho, Jaehoon Jung, Seoae Cho, Kwondo Kim, Seung-Tae Chung, Mi Gyeong Kim, Kyung Min Choi, Huibae Kim
Publikováno v:
Scientific Reports
Scientific Reports, Vol 7, Iss 1, Pp 1-8 (2017)
Scientific Reports, Vol 7, Iss 1, Pp 1-8 (2017)
In inbred mouse lines, there is generally little genetic difference between individuals. This small genetic variability facilitates carrying out research on minute changes of various traits and the gene pool. Also, characterizing the diversity and de
Autor:
Seung-Eun Choi, Myeon-Woo Chung, Zewon Park, Jong-Yeol Choi, Jong-Gu Lee, Seok-Yong Lee, Woo-Yong Oh, Fen Jiang, Ju Hyun Lee, Sunae Ryu, Han-Sung Na
Publikováno v:
Pharmacogenomics. 18(5)
Aim: To investigate the combined effects of SLCO1B1 and ABCB1 genotypes on the pharmacokinetics of simvastatin and its active metabolite simvastatin acid, in relation to CYP3A4 inhibition. Methods: We conducted a single-dose pharmacokinetic study of