Zobrazeno 1 - 10
of 371
pro vyhledávání: '"Myeloproliferation"'
Publikováno v:
Diagnostics, Vol 13, Iss 12, p 2086 (2023)
Cases with low level JAK2 V617F mutations are increasingly detected; however, the clinical interpretation of the low allele JAK2 burden may be challenging. The aim of this study is to analyze and compare the bone marrow morphology and peripheral bloo
Externí odkaz:
https://doaj.org/article/fb18dfe379694b019000f272b90dc3e6
Autor:
Claudio Tripodo, Barbara Bassani, Elena Jachetti, Valeria Cancila, Claudia Chiodoni, Paola Portararo, Laura Botti, Cesare Valenti, Milena Perrone, Maurilio Ponzoni, Patrizia Comoli, Mara Lecchi, Paolo Verderio, Antonio Curti, Mario P Colombo, Sabina Sangaletti
Publikováno v:
eLife, Vol 11 (2022)
Neutrophil extracellular traps (NETs) are web-like chromatin structures composed by dsDNA and histones, decorated with antimicrobial proteins. Their interaction with dendritic cells (DCs) allows DC activation and maturation toward presentation of NET
Externí odkaz:
https://doaj.org/article/a72a0e0c12714adaa226785d4975a485
Autor:
Paola Grazioli, Andrea Orlando, Nike Giordano, Claudia Noce, Giovanna Peruzzi, Gaia Scafetta, Isabella Screpanti, Antonio Francesco Campese
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
T-cell acute lymphoblastic leukemia (T-ALL) is an aggressive pediatric malignancy that arises from the transformation of immature T-cell progenitors and has no definitive cure. Notch signaling governs many steps of T cell development and its dysregul
Externí odkaz:
https://doaj.org/article/3d1558f8ab7343a29993ce09ad06fe3b
Publikováno v:
Diagnostics; Volume 13; Issue 12; Pages: 2086
Cases with low level JAK2 V617F mutations are increasingly detected; however, the clinical interpretation of the low allele JAK2 burden may be challenging. The aim of this study is to analyze and compare the bone marrow morphology and peripheral bloo
Autor:
Babarović, Emina, Marijić, Blažen, Vranić, Luka, Ban, Josipa, Valković, Toni, Hadžisejdić, Ita
Publikováno v:
Diagnostics
Volume 13
Issue 12
Volume 13
Issue 12
Cases with low level JAK2 V617F mutations are increasingly detected; however, the clinical interpretation of the low allele JAK2 burden may be challenging. The aim of this study is to analyze and compare the bone marrow morphology and peripheral bloo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::fb7588a924f35fc6b924b1cac7ce70df
https://doi.org/10.3390/diagnostics13122086
https://doi.org/10.3390/diagnostics13122086
Autor:
Jan Jacques Michiels, Hendrik De Raeve, Francisca Valster, Vincent Potters, Yonggoo Kim, Myungshin Kim
Publikováno v:
European Medical Journal, Vol 2, Iss 2, Pp 72-81 (2017)
Improved Clinical, Laboratory, Molecular, and Pathological (CLMP) 2017 criteria for myeloproliferative neoplasms (MPN) define the JAK2V617F trilinear MPNs as a broad continuum of essential thrombocythaemia (ET), polycythaemia vera (PV), masked PV, an
Externí odkaz:
https://doaj.org/article/5e22444b17c845d3bee2e3d9dbc630a4
Publikováno v:
Cells, Vol 9, Iss 8, p 1901 (2020)
Myeloproliferative neoplasms (MPNs) constitute a group of disorders identified by an overproduction of cells derived from myeloid lineage. The majority of MPNs have an identifiable driver mutation responsible for cytokine-independent proliferative si
Externí odkaz:
https://doaj.org/article/8ad9019407194270a573dd5debfff797
Publikováno v:
Hematology/Oncology and Stem Cell Therapy, Vol 14, Iss 3, Pp 252-256 (2021)
Primary myelofibrosis (PMF) is a subtype of BCR-ABL1 negative myeloproliferative neoplasm. Its characteristic features include clonal myeloproliferation, dysregulation of kinase signaling pathway, abnormal release of cytokines leading to fibrosis in
Publikováno v:
Journal of Cellular and Molecular Medicine
Thrombopoiesis had long been a challenging area of study due to the rarity of megakaryocyte precursors in the bone marrow and the incomplete understanding of its regulatory cytokines. A breakthrough was achieved in the early 1990s with the discovery
Publikováno v:
Hematol Oncol Clin North Am
Megakaryocytes give rise to platelets, which have a wide variety of functions in coagulation, immune response, inflammation, and tissue repair. Dysregulation of megakaryocytes is a key feature of in the myeloproliferative neoplasms, especially myelof