Zobrazeno 1 - 10
of 384
pro vyhledávání: '"Myeloid Cell Differentiation"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract Considering the key role of myeloid cell differentiation—related genes in the tumor microenvironment (TME), we aimed to build a prognostic risk model using these genes for Lung adenocarcinoma (LUAD). The mRNA gene expression profiles of LU
Externí odkaz:
https://doaj.org/article/430fa27589c14aeba0b57e9feafd9d9f
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Ariane Zutz, Christian Schölz, Stephanie Schneider, Virginia Pierini, Maximilian Münchhoff, Kathrin Sutter, Georg Wittmann, Ulf Dittmer, Rika Draenert, Johannes R. Bogner, Oliver T. Fackler, Oliver T. Keppler
Publikováno v:
Journal of Innate Immunity, Pp 1-11 (2020)
Classical antiviral restriction factors promote cellular immunity by their ability to interfere with virus replication and induction of their expression by proinflammatory cytokines such as interferons. The serine incorporator proteins SERINC3 and SE
Externí odkaz:
https://doaj.org/article/42b3355b4d974493a684a6e9a6207bc4
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Osteoclasts are multinucleated cells of hematopoietic origin which are critically involved in physiological and pathological bone resorption. They develop from myeloid progenitors through characteristic gene expression changes and intercellular fusio
Externí odkaz:
https://doaj.org/article/64ec1b46c2944d908ec61dcb05f75f29
Autor:
Clark A. Bonham, Dharshan Sivaraj, Michael T. Longaker, Jagannath Padmanabhan, Kellen Chen, Dominic Henn, Derrick C. Wan, Michael Januszyk, Artem A. Trotsyuk, Geoffrey C. Gurtner, Michelle Griffin, Hudson Choi Kussie
Publikováno v:
Advances in Wound Care. 11:466-478
Objective: After injury, humans and other mammals heal by forming fibrotic scar tissue with diminished function, and this healing process involves the dynamic interplay between resident cells withi...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41fcad70bdf094fd4b96b2dbcaaa004b
https://doi.org/10.1089/wound.2021.0036
https://doi.org/10.1089/wound.2021.0036
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Rosane Bittencourt, Evandro M. Fagundes, Letícia V. Costa-Lotufo, Juan L Coelho-Silva, Antonio R. Lucena-Araujo, Fabio R. Kerbauy, Katia B Pagnano, Diego A Pereira-Martins, Jean Carlos Lipreri da Silva, João Agostinho Machado-Neto, Raul Am Melo, Priscila Santos Scheucher, Fabiola Traina, Eduardo Magalhães Rego, E.C. Nunes, Luisa C A Koury, Hugo Passos Vicari, Lorena Lobo de Figueiredo-Pontes, Keli Lima
Publikováno v:
Investigational New Drugs. 40:438-452
Stathmin 1 (STMN1) is a microtubule-destabilizing protein highly expressed in hematological malignancies and involved in proliferation and differentiation. Although a previous study found that the PML-RARα fusion protein, which contributes to the pa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::29839a95a92233c3d2c3c2cd9bcb4b9d
https://doi.org/10.1007/s10637-021-01197-0
https://doi.org/10.1007/s10637-021-01197-0
Autor:
Pengcheng Zhang, Yang Zhou, Phillip M. Galbo, Lianzhong Zhao, Shaowei Qiu, Deyou Zheng, Rui Lu, Xinyue Zhou, Chunliang Li, Ravi Bhatia, Sajesan Aryal, Hao Zhang
Publikováno v:
Blood Advances
Key Points MEF2D is highly expressed in MLL-rearranged AML and required for leukemia development in vitro and in vivo.MEF2D suppresses CEBPE-mediated myeloid differentiation in AML.
Visual Abstract
Acute myeloid leukemia (AML) with MLL-rear
Visual Abstract
Acute myeloid leukemia (AML) with MLL-rear
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03d371119dc32647922fb1b32d123dc9
http://europepmc.org/articles/PMC8759131
http://europepmc.org/articles/PMC8759131
Autor:
Marina Pretolani, Yashaswi Shrestha, Jingya Wang, Fatima Hamidi, Roland Kolbeck, Jincheng Wu, Michel Aubier, Valérie Besnard, Alison A. Humbles, Alan M. Copenhaver, Rania Dagher, Aaron A Berlin, Xiaotao Qu, Rajiv Raja, Gregory Gautier, Marielle Maret
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-19 (2020)
Nature Communications
Nature Communications
Evidence points to an indispensable function of macrophages in tissue regeneration, yet the underlying molecular mechanisms remain elusive. Here we demonstrate a protective function for the IL-33-ST2 axis in bronchial epithelial repair, and implicate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14e12a9c411432f2762d55a189b0d419
https://doaj.org/article/dfa2aff3dc9744c0adab9ba6f648aaa3
https://doaj.org/article/dfa2aff3dc9744c0adab9ba6f648aaa3
Publikováno v:
Oncotarget. 11:1017-1036
Although ATRA represents a successful differentiation therapy for APL, it is largely ineffective for non-APL AMLs. Hence combination therapies using an agent targeting ATRA-regulated molecules that drive cell differentiation/arrest are of interest. U
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::644c7b9a5b96656b36c72dfac3507f9d
https://doi.org/10.18632/oncotarget.27508
https://doi.org/10.18632/oncotarget.27508