Zobrazeno 1 - 10
of 16 422
pro vyhledávání: '"Myelodysplastic Syndrome"'
Autor:
Venkat Chittapragada, Aishwarya Karthikeyan, Anand Balakrishnan, Sudhanshi Raina, Jasmina Ahluwalia, Reena Das, Pankaj Malhotra, Sreejesh Sreedharanunni
Publikováno v:
Turkish Journal of Hematology, Vol 41, Iss 4, Pp 275-278 (2024)
Externí odkaz:
https://doaj.org/article/a0e16973e1984429992a6a0015583e91
Publikováno v:
Current Issues in Molecular Biology, Vol 46, Iss 11, Pp 12061-12074 (2024)
Objective: Protein tyrosine phosphatase non-receptor type 6 (PTPN6) is a cytoplasmic phosphatase that acts as a key regulatory protein in cell signaling to control inflammation and cell death. In order to investigate the role of PTPN6 in hematologic
Externí odkaz:
https://doaj.org/article/41a0504c0fc1484e9fd296326454c8f4
Publikováno v:
Онкогематология, Vol 19, Iss 3, Pp 149-152 (2024)
Evaluation of bone marrow cytogenetic abnormalities in myelodysplastic syndrome is of great importance for confirming the clonal disease nature, determining the prognosis and choosing treatment tactics. Cytogenetic abnormalities are detected in 40–
Externí odkaz:
https://doaj.org/article/327168e796a749ba9af2c9bf4e4b2732
Autor:
Naomi Kawashima, Yasuo Kubota, Carlos Bravo-Perez, Luca Guarnera, Nakisha D. Williams, Arda Durmaz, Michaela Witt, Arooj Ahmed, Carmelo Gurnari, Jaroslaw P. Maciejewski, Valeria Visconte
Publikováno v:
Journal of Hematology & Oncology, Vol 17, Iss 1, Pp 1-6 (2024)
Abstract DNA methyltransferase 3 A mutations (DNMT3A MT) are frequent in myeloid neoplasia (MN) and mostly heterozygous. However, cases with multiple DNMT3A MT can be also encountered but their clinical and genetic landscape remains unexplored. We re
Externí odkaz:
https://doaj.org/article/eb8828e15ae0440189a9cfafde31b70a
Autor:
Vivi M. Srivastava, Sukesh Chandran Nair, Melvin Joy, Marie-Therese Manipadam, Uday P. Kulkarni, Anup J. Devasia, N.A Fouzia, Anu Korula, Kavitha M. Lakshmi, L. Jeyaseelan, Aby Abraham, Alok Srivastava
Publikováno v:
Molecular Cytogenetics, Vol 17, Iss 1, Pp 1-18 (2024)
Abstract Background The karyotype is a major determinant of prognosis in myelodysplastic syndrome (MDS). Details of the cytogenetic profile of MDS in South Asia are limited because cytogenetic services are not widely available. Methods We performed a
Externí odkaz:
https://doaj.org/article/8c59fcca04984df3b38ee6051ccd4065
Autor:
Kevin Lee, Wimeth Dissanayake, Melissa MacLiesh, Cih-Li Hong, Zi Yin, Yuko Kawano, Christina M. Kaszuba, Hiroki Kawano, Emily R. Quarato, Brian Marples, Michael Becker, Jeevisha Bajaj, Laura M. Calvi, Shu-Chi A. Yeh
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Recent advances in imaging suggested that spatial organization of hematopoietic cells in their bone marrow microenvironment (niche) regulates cell expansion, governing progression, and leukemic transformation of hematological clonal disorder
Externí odkaz:
https://doaj.org/article/39066cfbf9da4bac8aa29d11c5369e48
Autor:
Xinyu Guo, Wenyan Jin, Yuchen Wen, Zhiqin Wang, Xiaotong Ren, Zhaoyun Liu, Rong Fu, Zhigang Cai, Lijuan Li
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-16 (2024)
Abstract Background Myelodysplastic syndrome (MDS) is a complicated hematopoietic malignancy characterized by bone marrow (BM) dysplasia with symptoms like anemia, neutropenia, or thrombocytopenia. MDS exhibits considerable heterogeneity in prognosis
Externí odkaz:
https://doaj.org/article/c5c0e8f4b0e844d2a0ad9963d12ce26e
Publikováno v:
Cancer Management and Research, Vol Volume 16, Pp 753-760 (2024)
Shengping Gong,1 Cong Shi2 1Cancer Radiotherapy and Chemotherapy Center, the First Affiliated Hospital of Ningbo University, Ningbo, Zhejiang, People’s Republic of China; 2Laboratory of Stem Cell Transplantation, the First Affiliated Hospital of Ni
Externí odkaz:
https://doaj.org/article/984ec946521d4b5a81bcae8a524970d4
Autor:
Kazuki Yanagida, Taketo Kawai, Toyoshi Seito, Kensuke Matsumoto, Tomoyuki Kaneko, Tohru Nakagawa
Publikováno v:
IJU Case Reports, Vol 7, Iss 4, Pp 316-319 (2024)
Introduction Enfortumab vedotin is an antibody‐drug conjugate targeting Nectin‐4 for the treatment of advanced urothelial carcinoma in patients previously treated with platinum‐containing chemotherapy and immune checkpoint inhibitors. Common ad
Externí odkaz:
https://doaj.org/article/5e29a65451b64a51a435a67d2bf73a9d
Autor:
Rami Abdulbaki, Sheeja T. Pullarkat
Publikováno v:
Current Oncology, Vol 31, Iss 5, Pp 2353-2363 (2024)
Myelodysplastic neoplasm (MDS) is a heterogeneous group of clonal hematological disorders that originate from the hematopoietic and progenitor cells and present with cytopenias and morphologic dysplasia with a propensity to progress to bone marrow fa
Externí odkaz:
https://doaj.org/article/2c36488d80a449828d8aad4a71d9d58a