Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Myelin Sheath/metabolism"'
Autor:
Kole, Koen, Voesenek, Bas J B, Brinia, Maria E, Petersen, Naomi, Kole, Maarten H P, Sub Cell Biology, Celbiologie
Publikováno v:
Nature Communications, 13(1). Nature Publishing Group
Parvalbumin-expressing (PV+) basket cells are fast-spiking inhibitory interneurons that exert critical control over local circuit activity and oscillations. PV+ axons are often myelinated, but the electrical and metabolic roles of interneuron myelina
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d90827369728c0a0822e25e49731f9d
https://doi.org/10.1038/s41467-022-35350-x
https://doi.org/10.1038/s41467-022-35350-x
Autor:
Jemima J. Burden, Lucy Brooks, Zane Jaunmuktane, Daniela Kocher, Simona Parrinello, Megan Woodberry, Luca Richards, Leila Zakka, Steven M. Pollard, Sebastian Brandner, Melanie Clements, Peter B. Dirks, Michael J. Ellis, Gillian Morrison, Samuel Marguerat, Sara Castro Devesa
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Brooks, L J, Clements, M P, Burden, J J, Kocher, D, Richards, L, Devesa, S C, Zakka, L, Woodberry, M, Ellis, M, Jaunmuktane, Z, Brandner, S, Morrison, G, Pollard, S M, Dirks, P B, Marguerat, S & Parrinello, S 2021, ' The white matter is a pro-differentiative niche for glioblastoma ', Nature Communications, vol. 12, no. 1, pp. 2184 . https://doi.org/10.1038/s41467-021-22225-w
Nature Communications
Brooks, L J, Clements, M P, Burden, J J, Kocher, D, Richards, L, Devesa, S C, Zakka, L, Woodberry, M, Ellis, M, Jaunmuktane, Z, Brandner, S, Morrison, G, Pollard, S M, Dirks, P B, Marguerat, S & Parrinello, S 2021, ' The white matter is a pro-differentiative niche for glioblastoma ', Nature Communications, vol. 12, no. 1, pp. 2184 . https://doi.org/10.1038/s41467-021-22225-w
Nature Communications
Glioblastomas are hierarchically organised tumours driven by glioma stem cells that retain partial differentiation potential. Glioma stem cells are maintained in specialised microenvironments, but whether, or how, they undergo lineage progression out
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2c97b883e7b966040527328ba18effa
https://doaj.org/article/1dfd4c8671124520ac4d6ba779864aae
https://doaj.org/article/1dfd4c8671124520ac4d6ba779864aae
Autor:
Christine M. Eng, Reza Maroofian, Anna Rajab, GholamReza Karami Madani, Abolfazl Rad, Magdalena Walkiewicz, Fan Xia, Fatma Al-Jasmi, Stylianos E. Antonarakis, Martin Helmstädter, Marios Kambouris, Sebastian J. Arnold, Zornitza Stark, Miriam Schmidts, Sebastian Lunke, Atteeq U. Rehman, Francesco Vetrini, Maryam Najafi, Federico Santoni, Ehsan Ghayoor Karimiani, Lihadh Al-Gazali, Mari Tokita, Jozef Hertecant, Hanan Hamamy, Weimin He, Pengfei Liu, Periklis Makrythanasis, Hatem El-Shanti, Zeineb Bakey, Jill V. Hunter, Yaping Yang, Christopher M. Richmond, Kaman Wu, Andrea K. Petersen
Publikováno v:
Human Mutation, 40, 3, pp. 267-280
Human Mutation
Human mutation, vol. 40, no. 3, pp. 267-280
Human Mutation, 40, 267-280
Human Mutation
Human mutation, vol. 40, no. 3, pp. 267-280
Human Mutation, 40, 267-280
Next‐generation sequencing (NGS) has been instrumental in solving the genetic basis of rare inherited diseases, especially neurodevelopmental syndromes. However, functional workup is essential for precise phenotype definition and to understand the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d49d758337468ef5222cdd86eccb85e
https://hdl.handle.net/2066/201369
https://hdl.handle.net/2066/201369
Autor:
Jason R. Plemel, Aaron J. Moulson, Sohrab B. Manesh, Brett J. Hilton, Jie Liu, Peggy Assinck, Wolfram Tetzlaff, Greg J. Duncan
Publikováno v:
Nature Communications
Nature Communications, Vol 9, Iss 1, Pp 1-16 (2018)
Duncan, G J, Manesh, S B, Hilton, B J, Assinck, P, Liu, J, Moulson, A, Plemel, J R & Tetzlaff, W 2018, ' Locomotor recovery following contusive spinal cord injury does not require oligodendrocyte remyelination ', Nature Communications, vol. 9, 3066 . https://doi.org/10.1038/s41467-018-05473-1
Nature Communications 9(1), 3066 (2018). doi:10.1038/s41467-018-05473-1
Nature Communications, Vol 9, Iss 1, Pp 1-16 (2018)
Duncan, G J, Manesh, S B, Hilton, B J, Assinck, P, Liu, J, Moulson, A, Plemel, J R & Tetzlaff, W 2018, ' Locomotor recovery following contusive spinal cord injury does not require oligodendrocyte remyelination ', Nature Communications, vol. 9, 3066 . https://doi.org/10.1038/s41467-018-05473-1
Nature Communications 9(1), 3066 (2018). doi:10.1038/s41467-018-05473-1
Remyelination occurs after spinal cord injury (SCI) but its functional relevance is unclear. We assessed the necessity of myelin regulatory factor (Myrf) in remyelination after contusive SCI by deleting the gene from platelet-derived growth factor re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5933f6aa6c3d7fc8203d8644e2007c29
https://doi.org/10.1038/s41467-018-05473-1
https://doi.org/10.1038/s41467-018-05473-1
Autor:
Ruben Schmidt, Linda S. de Vries, Siemon C. de Lange, Manon J.N.L. Benders, Martijn P. van den Heuvel, Kristin Keunen, Pim Moeskops, Lisanne J. Stolwijk, Ivana Išgum, Hannelore K. van der Burgh, Marcel A. de Reus
Publikováno v:
Pediatric Research, 84, 829. Lippincott Williams and Wilkins
Keunen, K, van der Burgh, H K, de Reus, M A, Schmidt, R, de Lange, S C, de Vries, L S, Benders, M J & van den Heuvel, M P 2018, ' Early human brain development : insights into macroscale connectome wiring ', Pediatric Research, vol. 84, no. 6, pp. 829-836 . https://doi.org/10.1038/s41390-018-0138-1
Pediatric research, 84(6), 829-836. Lippincott Williams and Wilkins
Pediatric Research, 84(6), 829-836. Lippincott Williams and Wilkins
Keunen, K, van der Burgh, H K, de Reus, M A, Moeskops, P, Schmidt, R, Stolwijk, L J, de Lange, S C, Išgum, I, de Vries, L S, Benders, M J & van den Heuvel, M P 2018, ' Early human brain development : insights into macroscale connectome wiring ', Pediatric Research, vol. 84, no. 6, pp. 829-836 . https://doi.org/10.1038/s41390-018-0138-1
Keunen, K, van der Burgh, H K, de Reus, M A, Schmidt, R, de Lange, S C, de Vries, L S, Benders, M J & van den Heuvel, M P 2018, ' Early human brain development : insights into macroscale connectome wiring ', Pediatric Research, vol. 84, no. 6, pp. 829-836 . https://doi.org/10.1038/s41390-018-0138-1
Pediatric research, 84(6), 829-836. Lippincott Williams and Wilkins
Pediatric Research, 84(6), 829-836. Lippincott Williams and Wilkins
Keunen, K, van der Burgh, H K, de Reus, M A, Moeskops, P, Schmidt, R, Stolwijk, L J, de Lange, S C, Išgum, I, de Vries, L S, Benders, M J & van den Heuvel, M P 2018, ' Early human brain development : insights into macroscale connectome wiring ', Pediatric Research, vol. 84, no. 6, pp. 829-836 . https://doi.org/10.1038/s41390-018-0138-1
BACKGROUND: Early brain development is closely dictated by distinct neurobiological principles. Here, we aimed to map early trajectories of structural brain wiring in the neonatal brain.METHODS: We investigated structural connectome development in 44
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::218318c8d683b84f88932d5446e68246
https://dspace.library.uu.nl/handle/1874/377062
https://dspace.library.uu.nl/handle/1874/377062
Autor:
Maria Antonietta Davoli, Kathryn Vaillancourt, Alicja Gasecka, Gang G. Chen, Vanessa Larivière, John Kim, Marina Wakid, Carl Ernst, Meghan Shaw, Josée Prud'homme, Léon C van Kempen, Naguib Mechawar, Daniel Côté, Alexandre Bramoullé, Sarah Barnett-Burns, Arnaud Tanti, Gustavo Turecki, Michael J. Meaney, Volodymyr Yerko, Marc-Aurele Chay, Marie-Noël M’Boutchou, Tie-Yuan Zhang, Jean-François Théroux, Jennie Yang, Daniel Almeida, Yi Zhou, Pierre-Eric Lutz
Publikováno v:
American Journal of Psychiatry
American Journal of Psychiatry, American Psychiatric Publishing, 2017, 174 (12), pp.1185-1194. ⟨10.1176/appi.ajp.2017.16111286⟩
American Journal of Psychiatry, 174(12), 1185-1194. AMER PSYCHIATRIC PUBLISHING, INC
American Journal of Psychiatry, American Psychiatric Publishing, 2017, 174 (12), pp.1185-1194. ⟨10.1176/appi.ajp.2017.16111286⟩
American Journal of Psychiatry, 174(12), 1185-1194. AMER PSYCHIATRIC PUBLISHING, INC
OBJECTIVE: Child abuse has devastating and long-lasting consequences, considerably increasing the lifetime risk of negative mental health outcomes such as depression and suicide. Yet the neurobiological processes underlying this heightened vulnerabil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c91aaf4624bfbee7f31023b1afadff3a
https://hal.archives-ouvertes.fr/hal-02437484
https://hal.archives-ouvertes.fr/hal-02437484
Autor:
Guo, Jiasong, Wang, Leiming, Zhang, Yang, Wu, Jiawen, Arpag, Sezgi, Hu, Bo, Imhof, Beat, Tian, Xinxia, Carter, Bruce D, Suter, Ueli, Li, Jun
Publikováno v:
Annals of neurology
Annals of Neurology, Vol. 75, No 2 (2014) pp. 255-65
Annals of Neurology, Vol. 75, No 2 (2014) pp. 255-65
OBJECTIVE The peripheral myelin protein 22 (PMP22) gene is associated with the most common types of inherited neuropathies including hereditary neuropathy with liability to pressure palsies (HNPP) caused by PMP22 deficiency. However the function of P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::b45576f8c130534e7c6f890832b8c59d
Autor:
Beat A. Imhof, Peter J. Coffey, Rime Madani, Alexander Lobrinus, Ralf H. Adams, Dominique Ducrest-Gay, Richard Reynolds, Michel Aurrand-Lions, Dorothée Caille, Sussan Nourshargh, Yiangos Yiangou, Thomas E. Salt, Praveen Anand, Owain W. Howell, Alan S.L. Yu, Paolo Meda, Christoph Scheiermann
Publikováno v:
Science, Vol. 318, No 5855 (2007) pp. 1472-1475
JAM-C is an adhesion molecule that is expressed on cells within the vascular compartment and epithelial cells and, to date, has been largely studied in the context of inflammatory events. Using immunolabeling procedures in conjunction with confocal a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89edafe59f69d541b2264c97272da1cc
https://doi.org/10.1126/science.1149276
https://doi.org/10.1126/science.1149276
Autor:
Christine Brabeck, Adriano Aguzzi, Markus Tolnay, Hartmut H. Niemann, Frank Baumann, Mathias Heikenwalder, Ulrich Kloz, Jens Pahnke, Thomas Rülicke, Alexander Bürkle
Publikováno v:
The EMBO Journal. 26:538-547
PrP(C)-deficient mice expressing prion protein variants with large amino-proximal deletions (termed PrP(DeltaF)) suffer from neurodegeneration, which is rescued by full-length PrP(C). We now report that expression of PrP(DeltaCD), a PrP variant lacki
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2529bafb4cd6f4196e9137ffbac41aa3
https://doi.org/10.1038/sj.emboj.7601510
https://doi.org/10.1038/sj.emboj.7601510
Autor:
Corell, Mikael, Wicher, Grzegorz, Radomska, Katarzyna J, Daglikoca, Emine Duygu, Godskesen, Randi Elberg, Fredriksson, Robert, Benedikz, Eirikur, Magnaghi, Valerio, Fex Svenningsen, Åsa
Publikováno v:
Corell, M, Wicher, G, Radomska, K J, Daglikoca, E D, Godskesen, R E, Fredriksson, R, Benedikz, E, Magnaghi, V & Fex Svenningsen, Å 2015, ' GABA and its B-receptor are present at the node of Ranvier in a small population of sensory fibers, implicating a role in myelination ', Journal of Neuroscience Research, vol. 93, no. 2, pp. 285-295 . https://doi.org/10.1002/jnr.23489
The γ-aminobutyric acid (GABA) type B receptor has been implicated in glial cell development in the peripheral nervous system (PNS), although the exact function of GABA signaling is not known. To investigate GABA and its B receptor in PNS developmen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______3062::563398ddb714f8954fb86719ab934923
https://portal.findresearcher.sdu.dk/da/publications/e2027de6-ec07-456f-b79a-3165f618f625
https://portal.findresearcher.sdu.dk/da/publications/e2027de6-ec07-456f-b79a-3165f618f625