Zobrazeno 1 - 10
of 6 313
pro vyhledávání: '"Myd88"'
Autor:
Duško Lainšček, Simon Horvat, Klemen Dolinar, Filip Ivanovski, Rok Romih, Sergej Pirkmajer, Roman Jerala, Mateja Manček-Keber
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-14 (2024)
Abstract Various signaling pathways are essential for both the innate immune response and the maintenance of cell homeostasis, requiring coordinated interactions among them. In this study, a mutation in the caspase-1 recognition site within MyD88 abo
Externí odkaz:
https://doaj.org/article/a0262ff384b84a5ebcc836f4d93183e9
Autor:
Jie Deng, Mengdi Han, Jingyu Gong, Hongying Ma, Yinting Hao, Cheng Fang, Han Zhang, Jia Li, Wei Jiang
Publikováno v:
BMC Genomics, Vol 25, Iss 1, Pp 1-12 (2024)
Abstract Background Gram-negative bacteria are the main bacterial pathogens infecting Chinese giant salamanders (Andrias davidianus; CGS) in captivity and the wild, causing substantial economic losses in the CGS industry. However, the molecular mecha
Externí odkaz:
https://doaj.org/article/e93fdd8bbfa745f18bdf6602f79ab789
Publikováno v:
Journal of the Egyptian National Cancer Institute, Vol 36, Iss 1, Pp 1-10 (2024)
Abstract Background Diffuse large B-cell lymphoma (DLBCL) is an aggressive non-Hodgkin lymphoma and is characterized by heterogeneity in biology and clinical behavior. Mutations in the myeloid differentiation primary response 88 (MYD88) are found in
Externí odkaz:
https://doaj.org/article/14e4153fb8d24349833aeeee71ddeb8d
Autor:
Yandong Lv, Shuwei Guo, Lingtong Jin, Kai Wang, Yongsheng Li, Haonan Li, Yikang Lu, Hongzhou Liu
Publikováno v:
Cell Division, Vol 19, Iss 1, Pp 1-10 (2024)
Abstract Background Recent studies have highlighted the role of miR-5195-3p in suppressing cell growth in various cancers. However, the specific functional impact of miR-5195-3p in colorectal cancer (CRC) remain to be fully clarified. The importance
Externí odkaz:
https://doaj.org/article/cff05d4d64f842409961116668daab4c
Autor:
Jiang Zhu, Tanfang Zhou, Guangfeng Chen, Yuhui Wu, Xia Chen, Ya Song, Ayinula Tuohetali, Huijing Gao, Dongming Pang, Hao Wen, Kalibixiati Aimulajiang
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionAE and whether the inhibition of the MyD88 inflammatory pathway can enhance Ghrelin expression to collaboratively modulate AE progression remains unclear.MethodsIn this study, we evaluated Ghrelin serum levels and changes in TLR4/MyD88/NF
Externí odkaz:
https://doaj.org/article/6c214fe71b2c4e2ca7ee5dd3dfe75cf8
Autor:
Md. Habibur Rahaman, Sara J. Thygesen, Michael J. Maxwell, Hyoyoung Kim, Prerna Mudai, Jeffrey D. Nanson, Xinying Jia, Parimala R. Vajjhala, Andrew Hedger, Irina Vetter, Thomas Haselhorst, Avril A. B. Robertson, Brian Dymock, Thomas Ve, Mehdi Mobli, Katryn J. Stacey, Bostjan Kobe
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 39, Iss 1 (2024)
AbstractToll-like receptor (TLR) innate immunity signalling protects against pathogens, but excessive or prolonged signalling contributes to a range of inflammatory conditions. Structural information on the TLR cytoplasmic TIR (Toll/interleukin-1 rec
Externí odkaz:
https://doaj.org/article/dcf8b7e19c924597be45dfa99851bf23
Autor:
Bingnan Liu, Lijuan Fan, Youxia Wang, Hao Wang, Yuqi Yan, Shuai Chen, Ifen Hung, Chunxue Liu, Hong Wei, Liangpeng Ge, Wenkai Ren
Publikováno v:
Gut Microbes, Vol 16, Iss 1 (2024)
ABSTRACTMelatonin has various physiological effects, such as the maintenance of circadian rhythms, anti-inflammatory functions, and regulation of intestinal barriers. The regulatory functions of melatonin in gut microbiota remodeling have also been w
Externí odkaz:
https://doaj.org/article/f28281fdfc5f45f099a845aaaab4d556
Autor:
Jordan E. Rumford, Ailis Grieshaber, Samantha Lewiston, Jordan L. Reed, Samuel S. Long, Diana M. Mitchell
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 12 (2024)
Inflammation and microglia appear to be key factors influencing the outcome of retinal regeneration following acute retinal damage. Despite such findings, direct connection of microglia-specific inflammatory factors as drivers of regenerative respons
Externí odkaz:
https://doaj.org/article/05b1edce6397493fa122d3a0b9848c3b
Publikováno v:
Acta Poloniae Pharmaceutica, Vol 81, Iss 2, Pp 309-317 (2024)
Atopic dermatitis (AD) is a non-infectious inflammatory skin disease characterized by persistent itching of the skin, and it has become a global health problem with increasing incidence and complex pathogenesis. Momordin Ic (MMI) is a triterpenoid sa
Externí odkaz:
https://doaj.org/article/311cbb33f3c44ce09e55f09af379bd18
Autor:
Yujie Zhong, Geok Wee Tan, Johanna Bult, Nick Veltmaat, Wouter Plattel, Joost Kluiver, Roelien Enting, Arjan Diepstra, Anke van den Berg, Marcel Nijland
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-6 (2024)
Abstract Background Primary central nervous system lymphoma (PCNSL) are rare mature B-cell lymphoproliferative diseases characterized by a high incidence of MYD88 L265P and CD79B Y196 hotspot mutations. Diagnosis of PCNSL can be challenging. The aim
Externí odkaz:
https://doaj.org/article/58fa38028c8948688842739750545f68