Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Mycobacterium tuberculosis/drug effects/genetics"'
Autor:
Ricardo Antiparra, Pilar Lizárraga, Basilio Cieza, Patricia Sheen, David Requena, Robert H. Gilman, Mirko Zimic, Arnab Pain, Louis Grandjean, Bryan Lucero, Ruth McNerney, Taane G. Clark, David Moore, Elisa Roncal, Eduardo Gushiken
Publikováno v:
BMC Genomics
BMC Genomics, Vol 18, Iss 1, Pp 1-11 (2017)
BMC Genomics, Vol 18, Iss 1, Pp 1-11 (2017)
Background Tuberculosis (TB) is a major global health problem and drug resistance compromises the efforts to control this disease. Pyrazinamide (PZA) is an important drug used in both first and second line treatment regimes. However, its complete mec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6295e7c01d634f2c5e39b6060f8ae765
https://hdl.handle.net/20.500.12866/4586
https://hdl.handle.net/20.500.12866/4586
Autor:
Moradigaravand, Danesh, Grandjean, Louis, Martinez, Elena, Li, Hao, Zheng, Jun, Coronel, Jorge, Moore, David, Török, M Estée, Sintchenko, Vitali, Huang, Hairong, Javid, Babak, Parkhill, Julian, Peacock, Sharon J, Köser, Claudio U
Para-Aminosalicylic acid (PAS) is a group 4 antituberculosis agent. It targets folate metabolism as shown in Fig. S1 in the supplemental material, which also summarizes the known mechanisms of resistance to this prodrug. Recently, we reported a multi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::35d72bb08be4985f4778dcb5d9a6eed3
https://hdl.handle.net/20.500.12866/5233
https://hdl.handle.net/20.500.12866/5233
Autor:
Sharon J. Peacock, Claudio U. Köser, M. Estee Török, Jorge Coronel, Mirko Zimic, Caroline Colijn, Diepreye Ayabina, Robert H. Gilman, David Moore, Louis Grandjean, Christophe Fraser, Julian Parkhill, Simon R. Harris, Michelle Kendall, Tomatada Iwamoto
Publikováno v:
e0189838
PLoS ONE, Vol 12, Iss 12, p e0189838 (2017)
PLoS ONE
PLoS ONE, Vol 12, Iss 12, p e0189838 (2017)
PLoS ONE
Background Multidrug-resistant tuberculosis poses a major threat to the success of tuberculosis control programs worldwide. Understanding how drug-resistant tuberculosis evolves can inform the development of new therapeutic and preventive strategies.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00f74607cabb089f5d6e31e0c216ad93
https://doi.org/10.1371/journal.pone.0189838
https://doi.org/10.1371/journal.pone.0189838
Autor:
Lukas, Fenner, Matthias, Egger, Thomas, Bodmer, Ekkehardt, Altpeter, Marcel, Zwahlen, Katia, Jaton, Gaby E, Pfyffer, Sonia, Borrell, Olivier, Dubuis, Thomas, Bruderer, Hans H, Siegrist, Hansjakob, Furrer, Alexandra, Calmy, Jan, Fehr, Jesica Mazza, Stalder, Béatrice, Ninet, Erik C, Böttger, Sebastien, Gagneux, S, Yerly
Publikováno v:
Antimicrobial Agents and Chemotherapy
Antimicrobial Agents and Chemotherapy, Vol. 56, No 6 (2012) pp. 3047-53
Antimicrobial agents and chemotherapy
Antimicrobial Agents and Chemotherapy, Vol. 56, No 6 (2012) pp. 3047-53
Antimicrobial agents and chemotherapy
Bacterial factors may contribute to the global emergence and spread of drug-resistant tuberculosis (TB). Only a few studies have reported on the interactions between different bacterial factors. We studied drug-resistant Mycobacterium tuberculosis is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b96631a6c023eaf408dbf9f48cf77ab
https://pubmed.ncbi.nlm.nih.gov/22470121
https://pubmed.ncbi.nlm.nih.gov/22470121
We have developed a high-resolution melting (HRM) assay to scan for mutations in the rpoB, inhA, ahpC, and katG genes and/or promoter regions for the detection of rifampin and isoniazid resistance in Mycobacterium tuberculosis. For assay development,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1bb7283002f6b96ab22ac3773deaf8a
http://hdl.handle.net/10722/125140
http://hdl.handle.net/10722/125140
Autor:
Richard Y.T. Kao, Kwok-Yung Yuen, Wing-Hong Seto, Pak-Leung Ho, Tai Hing Lam, Wai Lok Woo, Wing-Cheong Yam, E. T. Y. Leung
Publikováno v:
Antimicrobial agents and chemotherapy. 50(3)
Multiplex allele-specific PCRs detecting katG codon 315 and mabA (bp -15) mutations could specifically identify 77.5% of isoniazid-resistant Mycobacterium tuberculosis strains in the South China region. One clinical isolate harboring InhA Ile194Thr w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0ea092d11ae610963ff10b230b690b9
https://pubmed.ncbi.nlm.nih.gov/16495272
https://pubmed.ncbi.nlm.nih.gov/16495272
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