Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Mychica Jones"'
Autor:
Qiu-Lan Ma, Cansheng Zhu, Marco Morselli, Trent Su, Matteo Pelligrini, Zhengqi Lu, Mychica Jones, Paul Denver, Daniel Castro, Xuelin Gu, Frances Relampagos, Kaitlin Caoili, Bruce Teter, Sally A. Frautschy, Gregory M. Cole
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Neuroinflammation plays a crucial role in the development and progression of Alzheimer's disease (AD), in which activated microglia are found to be associated with neurodegeneration. However, there is limited evidence showing how neuroinflammation an
Externí odkaz:
https://doaj.org/article/bdb572081193451080868c064d87e8c1
Autor:
Qiu-Lan Ma, Edmond Teng, Xiaohong Zuo, Mychica Jones, Bruce Teter, Evan Y. Zhao, Cansheng Zhu, Tina Bilousova, Karen H. Gylys, Liana G. Apostolova, Mary Jo LaDu, Mir Ahamed Hossain, Sally A. Frautschy, Gregory M. Cole
Publikováno v:
Neurobiology of Disease, Vol 114, Iss , Pp 120-128 (2018)
Synaptic neurodegeneration is thought to be an early event initiated by soluble β-amyloid (Aβ) aggregates that closely correlates with cognitive decline in Alzheimer disease (AD). Apolipoprotein ε4 (APOE4) is the most common genetic risk factor fo
Externí odkaz:
https://doaj.org/article/20a092811af24e62af1f42edd4697829
Autor:
Sally A. Frautschy, Giselle P. Lim, T. Chu, Mychica Jones, Xiaohong Zuo, R.M. Paul, Greg M. Cole, B. Teter, Takashi Morihara
Publikováno v:
Neurobiol Dis
Neurobiology of Disease, Vol 127, Iss, Pp 432-448 (2019)
Neurobiology of Disease, Vol 127, Iss, Pp 432-448 (2019)
Alzheimer's disease (AD) genetics implies a causal role for innate immune genes, TREM2 and CD33, products that oppose each other in the downstream Syk tyrosine kinase pathway, activating microglial phagocytosis of amyloid (Aβ). We report effects of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab4945054c799746e3b6ca1fc989e436
https://doi.org/10.1016/j.nbd.2019.02.015
https://doi.org/10.1016/j.nbd.2019.02.015
Autor:
Chansheng Zhu, Gregory M. Cole, Paul Denver, Sally A. Frautschy, Mychica Jones, Bruce Teter, Qiulan-Ma Ma
Publikováno v:
Alzheimer's & Dementia. 15
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::51fe3d1c3f7e58decb6eee2b9a6c12dd
https://doi.org/10.1016/j.jalz.2019.09.048
https://doi.org/10.1016/j.jalz.2019.09.048
Autor:
Liana G. Apostolova, Evan Y. Zhao, Tina Bilousova, Bruce Teter, Qiu-Lan Ma, Mary Jo LaDu, Edmond Teng, Mir Ahamed Hossain, Karen H. Gylys, Xiaohong Zuo, Sally A. Frautschy, Gregory M. Cole, Mychica Jones, Cansheng Zhu
Publikováno v:
Neurobiol Dis
Neurobiology of Disease, Vol 114, Iss, Pp 120-128 (2018)
Neurobiology of Disease, Vol 114, Iss, Pp 120-128 (2018)
Synaptic neurodegeneration is thought to be an early event initiated by soluble β-amyloid (Aβ) aggregates that closely correlates with cognitive decline in Alzheimer disease (AD). Apolipoprotein e4 (APOE4) is the most common genetic risk factor for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ccf590d272e608b5915bbb7ad063c0af
https://europepmc.org/articles/PMC8092920/
https://europepmc.org/articles/PMC8092920/
Autor:
Xiaohong Zuo, Shuxin Hu, Mychica Jones, Greg M. Cole, Qiu-Lan Ma, Panchanan Maiti, Sally A. Frautschy
Publikováno v:
Expert Review of Neurotherapeutics. 15:629-637
Curcumin, a polyphenolic antioxidant derived from the turmeric root has undergone extensive preclinical development, showing remarkable efficacy in wound repair, cancer and inflammatory disorders. This review addresses the rationale for its use in ne
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::547bc8125499492f17f5e7aa139d0f4f
https://doi.org/10.1586/14737175.2015.1044981
https://doi.org/10.1586/14737175.2015.1044981
Publikováno v:
Alzheimer's & Dementia. 15:P544-P544
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5c3d1497601e274a9f5badf2aea1b313
https://doi.org/10.1016/j.jalz.2019.06.4472
https://doi.org/10.1016/j.jalz.2019.06.4472
Autor:
Edmond Teng, Sally A. Frautschy, Mary Jo LaDu, Mychica Jones, Liana G. Apostolova, Ma Qiulan, Greg M. Cole, Xiaohong Zuo, Bruce Teter
Publikováno v:
Alzheimer's & Dementia. 12
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bfb983b7aa652bf2d669a3cad00fad69
https://doi.org/10.1016/j.jalz.2016.06.1807
https://doi.org/10.1016/j.jalz.2016.06.1807
Autor:
Dorothy G. Flood, Sally A. Frautschy, Nagichettiar Satyamurthy, Ping-Ping Chen, Stephen P. Trusko, Gary W. Small, Sung-Cheng Huang, Graham B. Cole, Fusheng Yang, Vladimir Kepe, Jie Liu, Edmond Teng, Jorge R. Barrio, Gregory M. Cole, Mychica Jones
Publikováno v:
Neurobiology of Disease, Vol 43, Iss 3, Pp 565-575 (2011)
In vivo detection of Alzheimer's disease (AD) neuropathology in living patients using positron emission tomography (PET) in conjunction with high affinity molecular imaging probes for β-amyloid (Aβ) and tau has the potential to assist with early di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd1686c2b6a342a879185eeacf5c016e
https://doi.org/10.1016/j.nbd.2011.05.003
https://doi.org/10.1016/j.nbd.2011.05.003
Autor:
Greg M. Cole, Peter Davies, Aynun N. Begum, Oliver J. Ubeda, Sally A. Frautschy, Beverly Hudspeth Beech, Ping-Ping Chen, Fusheng Yang, Peter Kim, Shuxin Hu, Mike S. Oh, Qiu-Lan Ma, Walter Beech, Mychica Jones
Publikováno v:
Neurobiology of Disease, Vol 33, Iss 2, Pp 193-206 (2009)
The dysregulation of glycogen synthase kinase-3 (GSK3) has been implicated in Alzheimer disease (AD) pathogenesis and in Abeta-induced neurotoxicity, leading us to investigate it as a therapeutic target in an intracerebroventricular Abeta infusion mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::587ce8395377a53e454810721f982868
http://www.sciencedirect.com/science/article/pii/S0969996108002520
http://www.sciencedirect.com/science/article/pii/S0969996108002520