Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Myan Do"'
Autor:
Diana Gumber, Myan Do, Neya Suresh Kumar, Pooja R Sonavane, Christina C N Wu, Luisjesus S Cruz, Stephanie Grainger, Dennis Carson, Terry Gaasterland, Karl Willert
Publikováno v:
eLife, Vol 9 (2020)
WNT proteins are secreted symmetry breaking signals that interact with cell surface receptors of the FZD family to regulate a multitude of developmental processes. Studying selectivity between WNTs and FZDs has been hampered by the paucity of purifie
Externí odkaz:
https://doaj.org/article/988e7a735dd744bdb503d91be2727265
Autor:
Jingwei Ma, Myan Do, Mark A Le Gros, Charles S Peskin, Carolyn A Larabell, Yoichiro Mori, Samuel A Isaacson
Publikováno v:
PLoS Computational Biology, Vol 16, Iss 11, p e1008356 (2020)
For a chemical signal to propagate across a cell, it must navigate a tortuous environment involving a variety of organelle barriers. In this work we study mathematical models for a basic chemical signal, the arrival times at the nuclear membrane of p
Externí odkaz:
https://doaj.org/article/e684153658db454b9eee17439c2346d5
Autor:
Myan Do, Karl Willert, Pooja R Sonavane, Stephen R. Adams, Edwin F. Juarez, Dennis A. Carson, Alessandra Rodriguez y Baena, Christina C.N. Wu, Charmi Patel, Jason Ross, Sunil J. Advani, Jill P. Mesirov
Publikováno v:
Mol Cancer Ther
Although WNT signaling is frequently dysregulated in solid tumors, drugging this pathway has been challenging due to off-tumor effects. Current clinical pan-WNT inhibitors are nonspecific and lead to adverse effects, highlighting the urgent need for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08161eb672df0fb662a6172e94f4f4ad
https://doi.org/10.1158/1535-7163.mct-21-0548
https://doi.org/10.1158/1535-7163.mct-21-0548
Autor:
Xiao-Hua Li, Benjamin Goldenson, Jaya Lakshmi Thangaraj, Matthew Gynn, Diana Gumber, Myan Do, Karl Willert, Dan S. Kaufman
Publikováno v:
Cancer Research. 82:559-559
Switchable chimeric antigen receptors (sCAR) provide an important new strategy to precisely regulate CAR-mediated anti-tumor activity. The sCAR system combines a CAR that recognizes peptide neoepitope (PNE) with an injectable “switch” molecule th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c4f3b415660b85eb4d791134a18c24de
https://doi.org/10.1158/1538-7445.am2022-559
https://doi.org/10.1158/1538-7445.am2022-559
Autor:
Neya Suresh Kumar, Stephanie Grainger, Terry Gaasterland, Myan Do, Christina C.N. Wu, Karl Willert, Dennis A. Carson, Pooja R Sonavane, Luisjesus S Cruz, Diana Gumber
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6502cf7a7f7c19e166a49cb535e15dfd
https://doi.org/10.7554/elife.63060.sa2
https://doi.org/10.7554/elife.63060.sa2
Autor:
Stephanie Grainger, Myan Do, Luisjesus S Cruz, Christina C.N. Wu, Pooja R Sonavane, Karl Willert, Terry Gaasterland, Neya Suresh Kumar, Diana Gumber, Dennis A. Carson
Publikováno v:
eLife, Vol 9 (2020)
eLife
eLife
WNT proteins are secreted symmetry breaking signals that interact with cell surface receptors of the FZD family to regulate a multitude of developmental processes. Studying selectivity between WNTs and FZDs has been hampered by the paucity of purifie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::294820d8d6788e74279d35692fd5cd27
https://elifesciences.org/articles/63060
https://elifesciences.org/articles/63060
Autor:
Carolyn A. Larabell, Samuel A. Isaacson, Jingwei Ma, Charles S. Peskin, Mark A. Le Gros, Yoichiro Mori, Myan Do
Publikováno v:
PLoS Computational Biology
PLoS computational biology, vol 16, iss 11
PLoS Computational Biology, Vol 16, Iss 11, p e1008356 (2020)
PLoS computational biology, vol 16, iss 11
PLoS Computational Biology, Vol 16, Iss 11, p e1008356 (2020)
For a chemical signal to propagate across a cell, it must navigate a tortuous environment involving a variety of organelle barriers. In this work we study mathematical models for a basic chemical signal, the arrival times at the nuclear membrane of p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6e95487610c64713316fe7c5fe7bfdd
Autor:
Myan Do, Christina C.N. Wu, Karl Willert, Sunil J. Advani, Dennis A. Carson, Stephen R. Adams
Publikováno v:
Cancer Research. 81:1848-1848
WNT signaling is frequently dysregulated in cancers. However, pan-WNT inhibitors regularly induce adverse effects in patients, mostly notably in bone, creating a need for more specific WNT-pathway targeting strategies. Frizzled-7 (FZD7), a cell-surfa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7282d9c2cdcfcc4a067e9319fc6d6005
https://doi.org/10.1158/1538-7445.am2021-1848
https://doi.org/10.1158/1538-7445.am2021-1848
Autor:
Myan Do, Gerry McDermott, Carolyn A. Larabell, Jian-Hua Chen, Mark A. Le Gros, Axel Ekman, Venera Weinhardt
Publikováno v:
Synchrotron Light Sources and Free-Electron Lasers ISBN: 9783319045078
Synchrotron Light Sources and Free-Electron Lasers
Synchrotron Light Sources and Free-Electron Lasers
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9a32c8c3b8f7e1b7567ea1fddb0ee73
https://doi.org/10.1007/978-3-319-04507-8_43-3
https://doi.org/10.1007/978-3-319-04507-8_43-3
Publikováno v:
Archives of Biochemistry and Biophysics. 581:111-121
We can learn much about cell function by imaging and quantifying sub-cellular structures, especially if this is done non-destructively without altering said structures. Soft x-ray tomography (SXT) is a high-resolution imaging technique for visualizin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e06bf1727754f1994f76b9c07c82c37a
https://doi.org/10.1016/j.abb.2015.01.011
https://doi.org/10.1016/j.abb.2015.01.011