Zobrazeno 1 - 10
of 85
pro vyhledávání: '"Mya C Schiess"'
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e52285 (2012)
α-synuclein is thought to play a key role in Parkinson's disease (PD) because it is the major protein in Lewy bodies, and because its gene mutations, duplication, and triplication are associated with early-onset PD. There are conflicting reports as
Externí odkaz:
https://doaj.org/article/2ca894eb815a44b59f7b2c86771e6b2d
Autor:
Herbert L. DuPont, Jessika Suescun, Zhi-Dong Jiang, Eric L. Brown, Heather T. Essigmann, Ashley S. Alexander, Andrew W. DuPont, Tehseen Iqbal, Netanya S. Utay, Michael Newmark, Mya C. Schiess
Publikováno v:
Frontiers in Neurology, Vol 14 (2023)
Background and purposeThe intestinal microbiome plays a primary role in the pathogenesis of neurodegenerative disorders and may provide an opportunity for disease modification. We performed a pilot clinical study looking at the safety of fecal microb
Externí odkaz:
https://doaj.org/article/88b4025447874d668ccffb35a579c6ce
Autor:
Christopher Adams, Jessika Suescun, Anam Haque, Kelly Block, Shivika Chandra, Timothy M. Ellmore, Mya C. Schiess
Publikováno v:
Clinical Parkinsonism & Related Disorders, Vol 8, Iss , Pp 100187- (2023)
Introduction: Motor classifications of Parkinson's Disease (PD) have been widely used. This paper aims to update a subtype classification using the MDS-UPDRS-III and determine if cerebrospinal neurotransmitter profiles (HVA and 5-HIAA) differ between
Externí odkaz:
https://doaj.org/article/189e682494784b5fbf9889eab23965bf
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Abstract Our objective is to derive a sequential decision-making rule on the combination of medications to minimize motor symptoms using reinforcement learning (RL). Using an observational longitudinal cohort of Parkinson’s disease patients, the Pa
Externí odkaz:
https://doaj.org/article/31c5e5c270414017a3711587b00d9e9a
Autor:
Eric L. Brown, Heather T. Essigmann, Kristi L. Hoffman, Ashley Alexander, Michael Newmark, Zhi-Dong Jiang, Jessika S. Ocampo, Mya C. Schiess, Craig L. Hanis, Herbert L. DuPont
Publikováno v:
Journal of Parkinson's Disease. :1-13
Background: Parkinson’s disease is a heterogeneous neurodegenerative disorder with distinctive gut microbiome patterns suggesting that interventions targeting the gut microbiota may prevent, slow, or reverse disease progression and severity. Object
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::936b9e7b58a77bfd7085f62df3f4e993
https://doi.org/10.3233/jpd-230066
https://doi.org/10.3233/jpd-230066
Autor:
Danilo Pena, Arko Barman, Jessika Suescun, Xiaoqian Jiang, Mya C. Schiess, Luca Giancardo, the Alzheimer's Disease Neuroimaging Initiative
Publikováno v:
Frontiers in Neuroscience, Vol 13 (2019)
Alzheimer's disease (AD) is the most common neurodegenerative disorder worldwide and is one of the leading sources of morbidity and mortality in the aging population. There is a long preclinical period followed by mild cognitive impairment (MCI). Cli
Externí odkaz:
https://doaj.org/article/4333297e73e04e718f53c92ddc67a1d8
Publikováno v:
Parkinson's Disease, Vol 2017 (2017)
Neuromodulation of subcortical areas of the brain as therapy to reduce Parkinsonian motor symptoms was developed in the mid-twentieth century and went through many technical and scientific advances that established specific targets and stimulation pa
Externí odkaz:
https://doaj.org/article/dc07fa5ca08e41c18316040c5a331e07
Autor:
Marie-Francoise Doursout, Jerome G. Saltarrelli, Christopher M. Adams, Sean I Savitz, Timothy M. Ellmore, Charles Green, Mya C. Schiess, Jessika Suescun
Publikováno v:
Movement Disorders
Background Neuroinflammation plays a key role in PD pathogenesis, and allogeneic bone marrow–derived mesenchymal stem cells can be used as an immunomodulatory therapy. Objective The objective of this study was to prove the safety and tolerability o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ee29ae37405d5c02c4764aaed5dbfc3
https://doi.org/10.1002/mds.28582
https://doi.org/10.1002/mds.28582
Publikováno v:
The Neurologist. 25:151-156
BACKGROUND: There is considerable debate regarding the use of intraoperative microelectrode recording (MER) in deep brain stimulation (DBS). OBJECTIVE: To determine if the use of intraoperative MER impacts the final position of the lead implant in DB
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::02e51279d5c53fde4797cb16fa8c9e35
https://doi.org/10.1097/nrl.0000000000000289
https://doi.org/10.1097/nrl.0000000000000289
Intrathecal Baclofen for Severe Spasticity: Longitudinal Data From the Product Surveillance Registry
Autor:
Robert J. Plunkett, Robert Spencer, Peter E. Konrad, Sam Eldabe, Todd Weaver, Lisa Molus, Mya C. Schiess, Katherine Stromberg
Publikováno v:
Neuromodulation
Objective To assist in the assessment of intrathecal baclofen (ITB) therapy risks and benefits by providing surgical intervention rate, safety, and elective device replacement rate data. Materials and methods An ongoing prospective, long-term, multic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22767db6c7dfda3e4090b5c38969f5da
https://doi.org/10.1111/ner.13097
https://doi.org/10.1111/ner.13097