Zobrazeno 1 - 10
of 24
pro vyhledávání: '"MyPhuong T. Le"'
Autor:
Ana Andres-Hernando, Nanxing Li, Christina Cicerchi, Shinichiro Inaba, Wei Chen, Carlos Roncal-Jimenez, Myphuong T. Le, Michael F. Wempe, Tamara Milagres, Takuji Ishimoto, Mehdi Fini, Takahiko Nakagawa, Richard J. Johnson, Miguel A. Lanaspa
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
The polyol pathway, which converts glucose into sorbitol and fructose, is active in chronic conditions like hepatic steatosis and chronic kidney disease. Here, Andres-Hernandoet al. show that fructose production promotes renal injury and fructokinase
Externí odkaz:
https://doaj.org/article/f3cdc5cee4a04d45865650ca82efee0f
Publikováno v:
SLAS Technology. 26:555-571
The Purdue Make It system is a unique automated platform capable of small-scale in situ synthesis, screening small-molecule reactions, and performing direct label-free bioassays. The platform is based on desorption electrospray ionization (DESI), an
Autor:
Leah R Villegas, Christopher J Rivard, Brandi Hunter, Zhiying You, Carlos Roncal, Melanie S Joy, MyPhuong T Le
Publikováno v:
PLoS ONE, Vol 13, Iss 11, p e0207024 (2018)
ObjectiveFructose is commonplace in Western diets and is consumed primarily through added sugars as sucrose or high fructose corn syrup. High consumption of fructose has been linked to the development of metabolic disorders, such as cardiovascular di
Externí odkaz:
https://doaj.org/article/115a167d1c9c4c25963660aae3a1dab0
Publikováno v:
Journal of the American Society for Mass Spectrometry. 32:2261-2273
Using desorption electrospray ionization (DESI) as part of an automated high-throughput system, tandem mass spectra of the compounds in a pharmaceutical library were recorded in the positive mode under standardized conditions. Quality control filteri
Autor:
Wei Chen, Carlos A. Roncal-Jimenez, Miguel A. Lanaspa, Takahiko Nakagawa, Ana Andres-Hernando, Takuji Ishimoto, Tamara Milagres, Richard J. Johnson, Shinichiro Inaba, Nanxing Li, Mehdi A. Fini, MyPhuong T. Le, Christina Cicerchi, Michael F. Wempe
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
Acute kidney injury is associated with high mortality, especially in intensive care unit patients. The polyol pathway is a metabolic route able to convert glucose into fructose. Here we show the detrimental role of endogenous fructose production by t
Autor:
MyPhuong T. Le, Joseph M. Yracheta, Manal F. Abdelmalak, Richard J. Johnson, Laura G. Sánchez-Lozada, Javier Alfonso, Miguel A. Lanaspa
Publikováno v:
Mayo Clinic Proceedings. 90:813-823
Since the early 20th century, a marked increase in obesity, diabetes, and chronic kidney disease has occurred in the American Indian population, especially the Pima Indians of the Southwest. Here, we review the current epidemic and attempt to identif
Autor:
Christopher J. Rivard, Ronald J. Sokol, Kathryn Love-Osborne, Shikha S. Sundaram, MyPhuong T. Le, Richard J. Johnson, Kristen Robbins, Jillian S. Sullivan, Zhaoxing Pan
Publikováno v:
Pediatric Obesity. 10:188-195
Background: Fructose intake is associated with non-alcoholic fatty liver disease (NAFLD) development. Objective: The objective of this study was to measure fructose absorption/metabolism in paediatric NAFLD compared with obese and lean controls. Meth
Autor:
Melanie S. Joy, Brandi Hunter, Carlos Roncal, Leah R. Villegas, MyPhuong T. Le, Zhiying You, Christopher J. Rivard
Publikováno v:
PLoS ONE, Vol 13, Iss 11, p e0207024 (2018)
PLoS ONE
PLoS ONE
ObjectiveFructose is commonplace in Western diets and is consumed primarily through added sugars as sucrose or high fructose corn syrup. High consumption of fructose has been linked to the development of metabolic disorders, such as cardiovascular di
Autor:
Takuji Ishimoto, MyPhuong T. Le, Takahiko Nakagawa, L. Gabriela Sánchez-Lozada, Richard J. Johnson, Mohamed Shafiu, Yuri Y. Sautin, Miguel A. Lanaspa, Shikha S. Sundaram
Publikováno v:
Diabetes
The intake of added sugars, such as from table sugar (sucrose) and high-fructose corn syrup has increased dramatically in the last hundred years and correlates closely with the rise in obesity, metabolic syndrome, and diabetes. Fructose is a major co
Autor:
MyPhuong T. Le, Richard J. Johnson, Christopher J. Rivard, Brandi Hunter, Miguel A. Lanaspa, Jatinder Rana, Jeffrey D. Scholten, R. Keith Randolph, Christina Cicerchi
Publikováno v:
PLoS ONE, Vol 11, Iss 6, p e0157458 (2016)
PLoS ONE
PLoS ONE
Objective In developed countries with westernized diets, the excessive consumption of added sugar in beverages and highly refined and processed foods is associated with increased risk for obesity, diabetes, and cardiovascular diseases. As a major con