Heterozygosity testing and multiplex DNA panel screening as a potential tool to monitor health and inbreeding in a small, closed dog population

Autor: S. F. A. Keijser, H. Fieten, M. Vos-Loohuis, C. J. Piek, H. Anderson, J. Donner, I. Scholten, M. Nielen, J. W. Hesselink, F. G. van Steenbeek

Publikováno v: Canine Genetics and Epidemiology, Vol 5, Iss 1, Pp 1-9 (2018)

Abstract Background Selective breeding in populations with a limited effective population size may result in a loss of genetic diversity, which can cause an increased concentration of specific disease liability genes. The Dutch Shepherd Dog (DSD) in

Externí odkaz: https://doaj.org/article/75b07e0d4dde4606aaca1a3ecf59c8a6

DNA panel screening as a potential tool to monitor health and inbreeding in a small, closed dog population

Publikováno v: Canine genetics and epidemiology. 5(12)

Background: Selective breeding in populations with a limited effective population size may result in a loss of genetic diversity, which can cause an increased concentration of specific disease liability genes. The Dutch Shepherd Dog (DSD) in the Neth

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dris___00893::05ebea5a4f135b675425e1c407cd6eec
https://doi.org/10.1186/s40575-018-0068-6

Heterozygosity testing and multiplex DNA panel screening as a potential tool to monitor health and inbreeding in a small, closed dog population.

Autor: Keijser SFA; 1Expertise Centre Genetics of Companion Animals, Department of Clinical Sciences of Companion Animals, Faculty of Veterinary Medicine, Utrecht University, Yalelaan 108, 3584 CM Utrecht, The Netherlands., Fieten H; 1Expertise Centre Genetics of Companion Animals, Department of Clinical Sciences of Companion Animals, Faculty of Veterinary Medicine, Utrecht University, Yalelaan 108, 3584 CM Utrecht, The Netherlands., Vos-Loohuis M; 2Department of Clinical Sciences of Companion Animals, Faculty of Veterinary Medicine, Utrecht University, Yalelaan 108, 3584 CM Utrecht, The Netherlands., Piek CJ; 2Department of Clinical Sciences of Companion Animals, Faculty of Veterinary Medicine, Utrecht University, Yalelaan 108, 3584 CM Utrecht, The Netherlands., Anderson H; Genoscoper Laboratories Oy, P.O. Box 1040, 00251 Helsinki, Finland., Donner J; Genoscoper Laboratories Oy, P.O. Box 1040, 00251 Helsinki, Finland., Scholten I; Dutch Shepherd Dog Club, Vijfsprongweg 126, 6741 JC Lunteren, The Netherlands., Nielen M; 5Department of Farm Animal Health, Faculty of Veterinary Medicine, Utrecht University, Yalelaan 107, 3584 CM Utrecht, The Netherlands., Hesselink JW; 2Department of Clinical Sciences of Companion Animals, Faculty of Veterinary Medicine, Utrecht University, Yalelaan 108, 3584 CM Utrecht, The Netherlands., van Steenbeek FG; 2Department of Clinical Sciences of Companion Animals, Faculty of Veterinary Medicine, Utrecht University, Yalelaan 108, 3584 CM Utrecht, The Netherlands.

Publikováno v: Canine genetics and epidemiology [Canine Genet Epidemiol] 2018 Dec 28; Vol. 5, pp. 12. Date of Electronic Publication: 2018 Dec 28 (Print Publication: 2018).