Zobrazeno 1 - 10
of 59
pro vyhledávání: '"My-Hang Huynh"'
Autor:
Fengrong Wang, Michael J. Holmes, Hea Jin Hong, Pariyamon Thaprawat, Geetha Kannan, My-Hang Huynh, Tracey L. Schultz, M. Haley Licon, Sebastian Lourido, Wenzhao Dong, Jailson Brito Querido, William J. Sullivan, Seán E. O’Leary, Vern B. Carruthers
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract The parasite Toxoplasma gondii persists in its hosts by converting from replicating tachyzoites to latent bradyzoites housed in tissue cysts. The molecular mechanisms that mediate T. gondii differentiation remain poorly understood. Through a
Externí odkaz:
https://doaj.org/article/344823925b104d6a82ccf0c94f14d18f
Autor:
My-Hang Huynh, Vern B Carruthers
Publikováno v:
PLoS Pathogens, Vol 18, Iss 5, p e1010139 (2022)
The Toxoplasma gondii lytic cycle is a repetition of host cell invasion, replication, egress, and re-invasion into the next host cell. While the molecular players involved in egress have been studied in greater detail in recent years, the signals and
Externí odkaz:
https://doaj.org/article/fa67d43b132e42aaab4e93c6499ce56f
Autor:
My-Hang Huynh, Marijo S. Roiko, Angelica O. Gomes, Ellyn N. Schinke, Aric J. Schultz, Swati Agrawal, Christine A. Oellig, Travis R. Sexton, Jessica M. Beauchamp, Julie Laliberté, Komagal Kannan Sivaraman, Louis B. Hersh, Sheena McGowan, Vern B. Carruthers
Publikováno v:
mSphere, Vol 6, Iss 3 (2021)
After replicating within infected host cells, the single-celled parasite Toxoplasma gondiiT. gondii
Externí odkaz:
https://doaj.org/article/edd43c30582d46ed92946c373690f57b
Autor:
Geetha Kannan, Manlio Di Cristina, Aric J. Schultz, My-Hang Huynh, Fengrong Wang, Tracey L. Schultz, Matteo Lunghi, Isabelle Coppens, Vern B. Carruthers
Publikováno v:
mBio, Vol 10, Iss 4 (2019)
ABSTRACT Toxoplasma gondii is a ubiquitous pathogen that can cause encephalitis, congenital defects, and ocular disease. T. gondii has also been implicated as a risk factor for mental illness in humans. The parasite persists in the brain as slow-grow
Externí odkaz:
https://doaj.org/article/ae12df682df347df9a095dba059bb18f
Autor:
Alfredo J Guerra, Ou Zhang, Constance M E Bahr, My-Hang Huynh, James DelProposto, William C Brown, Zdzislaw Wawrzak, Nicole M Koropatkin, Vern B Carruthers
Publikováno v:
PLoS Pathogens, Vol 14, Iss 12, p e1007476 (2018)
Intracellular pathogens must egress from the host cell to continue their infectious cycle. Apicomplexans are a phylum of intracellular protozoans that have evolved members of the membrane attack complex and perforin (MACPF) family of pore forming pro
Externí odkaz:
https://doaj.org/article/a4c1cc508abb4092b26750a4c84d4163
A Toxoplasma gondii Ortholog of Plasmodium GAMA Contributes to Parasite Attachment and Cell Invasion
Autor:
My-Hang Huynh, Vern B. Carruthers
Publikováno v:
mSphere, Vol 1, Iss 1 (2016)
ABSTRACT Toxoplasma gondii and its Plasmodium kin share a well-conserved invasion process, including sequential secretion of adhesive molecules for host cell attachment and invasion. However, only a few orthologs have been shown to be important for e
Externí odkaz:
https://doaj.org/article/b0dbfbdced7e4b2a9b9dd9af86d3a223
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e64693 (2013)
Toxoplasma gondii critically relies on cell invasion as a survival strategy to evade immune clearance during infection. Although it was widely thought that Toxoplasma entry is parasite directed and that the host cell is largely a passive victim, rece
Externí odkaz:
https://doaj.org/article/21b9ed938ae045d5bbda9b706633f882
Autor:
Josh R Beck, Imilce A Rodriguez-Fernandez, Jessica Cruz de Leon, My-Hang Huynh, Vern B Carruthers, Naomi S Morrissette, Peter J Bradley
Publikováno v:
PLoS Pathogens, Vol 6, Iss 9, p e1001094 (2010)
Apicomplexans employ a peripheral membrane system called the inner membrane complex (IMC) for critical processes such as host cell invasion and daughter cell formation. We have identified a family of proteins that define novel sub-compartments of the
Externí odkaz:
https://doaj.org/article/98900d097e53426a9489b9c23a4c658d
Autor:
My-Hang Huynh, Vern B Carruthers
Publikováno v:
PLoS Pathogens, Vol 2, Iss 8, p e84 (2006)
Like its apicomplexan kin, the obligate intracellular protozoan Toxoplasma gondii actively invades mammalian cells and uses a unique form of gliding motility. The recent identification of several transmembrane adhesive complexes, potentially capable
Externí odkaz:
https://doaj.org/article/308ca16725034102856a5e730415c6e2
Autor:
Saima M. Sidik, Dylan Valleau, Yamilex Acevedo-Sánchez, Luiz C. Godoy, Charisse Flerida A. Pasaje, My-Hang Huynh, Vern B. Carruthers, Jacquin C. Niles, Sebastian Lourido
Apicomplexan parasites discharge specialized organelles called rhoptries upon host cell contact to mediate invasion. The events that drive rhoptry discharge are poorly understood, yet essential to sustain the apicomplexan parasitic life cycle. Rhoptr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::39cd3217756f9211693c1a2d57e98967
https://doi.org/10.1101/2022.11.28.518173
https://doi.org/10.1101/2022.11.28.518173