Zobrazeno 1 - 10
of 95
pro vyhledávání: '"My N Helms"'
Autor:
Charles A Downs, David Q Trac, Lisa H Kreiner, Amity F Eaton, Nicholle M Johnson, Lou Ann Brown, My N Helms
Publikováno v:
PLoS ONE, Vol 8, Iss 1, p e54750 (2013)
Chronic alcohol consumption is associated with increased incidence of ICU-related morbidity and mortality, primarily from acute respiratory distress syndrome (ARDS). However, the mechanisms involved are unknown. One explanation is that alcohol regula
Externí odkaz:
https://doaj.org/article/46a336638a184694a6b38d56af1fee19
Autor:
Kristi J. Warren, Emily M. Beck, Sean J. Callahan, My N. Helms, Elizabeth Middleton, Sean Maddock, Jason R. Carr, Dixie Harris, Denitza P. Blagev, Michael J. Lanspa, Samuel M. Brown, Robert Paine
Publikováno v:
Respiratory Research, Vol 24, Iss 1, Pp 1-10 (2023)
Abstract Exposure to e-cigarette vapors alters important biologic processes including phagocytosis, lipid metabolism, and cytokine activity in the airways and alveolar spaces. Little is known about the biologic mechanisms underpinning the conversion
Externí odkaz:
https://doaj.org/article/d62237b9698b4213a647b3386363745c
Autor:
Theodore G. Liou, Frederick R. Adler, Barbara C. Cahill, David R. Cox, James E. Cox, Garett J. Grant, Kimberly E. Hanson, Stephen C. Hartsell, Nathan D. Hatton, My N. Helms, Judy L. Jensen, Christiana Kartsonaki, Yanping Li, Daniel T. Leung, James E. Marvin, Elizabeth A. Middleton, Sandra M. Osburn‐Staker, Kristyn A. Packer, Salika M. Shakir, Anne B. Sturrock, Keith D. Tardif, Kristi J. Warren, Lindsey J. Waddoups, Lisa J. Weaver, Elizabeth Zimmerman, Robert Paine III
Publikováno v:
Physiological Reports, Vol 9, Iss 4, Pp n/a-n/a (2021)
Abstract COVID‐19 causes severe disease with poor outcomes. We tested the hypothesis that early SARS‐CoV‐2 viral infection disrupts innate immune responses. These changes may be important for understanding subsequent clinical outcomes. We obtai
Externí odkaz:
https://doaj.org/article/cad182d307d642e6bf3b48dd61e5b619
Publikováno v:
Physiology. 38
Background: Bronchopulmonary dysplasia (BPD) is a severe oxidative-stress induced lung disease that primarily affects premature infants requiring long term oxygen supplementation. BPD is characterized by attenuated lung development, fibrosis, inflamm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e1a946f4e4e4804b76fa0a903d03b807
https://doi.org/10.1152/physiol.2023.38.s1.5734926
https://doi.org/10.1152/physiol.2023.38.s1.5734926
Autor:
Theodore G. Liou, My N. Helms
Publikováno v:
Am J Respir Cell Mol Biol
Neutrophil extracellular traps increase cystic fibrosis (CF) airway inflammation. We hypothesized that macrophage exposure to neutrophil elastase (NE) would trigger the release of macrophage extracellular traps (METs), a novel mechanism to augment NE
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67d7f839c76c64b99c5ac1482ee82682
https://doi.org/10.1165/rcmb.2021-0423ed
https://doi.org/10.1165/rcmb.2021-0423ed
Autor:
Ingrid Iara Damas, Luccas Lavareze, João Figueira Scarini, Reydson Alcides de Lima-Souza, Carolina Emerick, Mayara Trevizol Gonçalves, Tayná Figueiredo-Maciel, Gustavo de Souza Vieira, Talita de Carvalho Kimura, Iara Gonçalves Aquino, João Paulo Gonçalves de Paiva, My N. Helms, Fernanda Viviane Mariano, Albina Altemani, Erika Said Abu Egal
Publikováno v:
Placenta. 131
Villitis of unknown etiology (VUE) is an inflammatory disease characterized by the infiltration of maternal CD8 +T cells into the placental villi. Although the pathogenesis of VUE is still debated, dysregulation of the immune system appears to be an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65b4191a7362f8822448f1a974c53637
https://pubmed.ncbi.nlm.nih.gov/36473393
https://pubmed.ncbi.nlm.nih.gov/36473393
Autor:
Tong Zhang, Nicholas J. Day, Matthew Gaffrey, Karl K. Weitz, Kwame Attah, Patrice N. Mimche, Robert Paine, Wei-Jun Qian, My N. Helms
Publikováno v:
Redox biology. 55
Preterm infants and patients with lung disease often have excess fluid in the lungs and are frequently treated with oxygen, however long-term exposure to hyperoxia results in irreversible lung injury. Although the adverse effects of hyperoxia are med
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0aef942d1f6e1e6ce148f048d19a69ba
https://pubmed.ncbi.nlm.nih.gov/35872399
https://pubmed.ncbi.nlm.nih.gov/35872399
Publikováno v:
Journal of cellular and molecular medicine. 26(14)
HMGB1 is a ubiquitously expressed protein localized in nucleus, cytoplasm, as well as secreted into extracellular space. Nuclear HMGB1 binds to DNAs and RNAs, regulating genomic stability and transcription. Cytoplasmic HMGB1 regulates autophagy throu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fccdd7902bb6d1c6dbf0aad33b76d8bd
https://pubmed.ncbi.nlm.nih.gov/35706377
https://pubmed.ncbi.nlm.nih.gov/35706377
Publikováno v:
The FASEB Journal. 36
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::22928d051c407334dd943fae43dfc456
https://doi.org/10.1096/fasebj.2022.36.s1.r6139
https://doi.org/10.1096/fasebj.2022.36.s1.r6139
Publikováno v:
The FASEB Journal. 36
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::06b804f844c67fba9bbe4326b72b5bb2
https://doi.org/10.1096/fasebj.2022.36.s1.r6055
https://doi.org/10.1096/fasebj.2022.36.s1.r6055