Zobrazeno 1 - 5
of 5
pro vyhledávání: '"My Linh T. Duong"'
Autor:
An Lu, Kelly L. Sharp, Wei-Chun Chang, Kevin M. Slawin, Slawomir P. Szymanski, Steven M. Toler, Ming Zhang, Eva Morschl, David M. Spencer, Matthew R. Collinson-Pautz, My Linh T. Duong, J. Henri Bayle, Mary E. Brandt, Aaron E. Foster
Publikováno v:
Molecular Therapy: Oncolytics, Vol 12, Iss, Pp 124-137 (2019)
Molecular Therapy Oncolytics
Molecular Therapy Oncolytics
Use of chimeric antigen receptors (CARs) as the basis of targeted adoptive T cell therapies has enabled dramatic efficacy against multiple hematopoietic malignancies, but potency against bulky and solid tumors has lagged, potentially due to insuffici
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ea3ccbe3a4f7ff4b8f73320ec846449
http://www.sciencedirect.com/science/article/pii/S2372770518300469
http://www.sciencedirect.com/science/article/pii/S2372770518300469
Autor:
Aaron E. Foster, Mary E. Brandt, Kevin M. Slawin, David M. Spencer, Matthew R. Collinson-Pautz, Pei-Yi Lin, Mariam Khalil, Nicholas P. Shinners, My Linh T. Duong, J. Henri Bayle, Aruna Mahendravada, Wei-Chun Chang, Ming Zhang, An Lu, Jeannette Crisostomo
Publikováno v:
Leukemia
Successful adoptive chimeric antigen receptor (CAR) T-cell therapies against hematological malignancies require CAR-T expansion and durable persistence following infusion. Balancing increased CAR-T potency with safety, including severe cytokine-relea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e30e133078c58b79fdbde0dbc893bc7
https://doi.org/10.1038/s41375-019-0417-9
https://doi.org/10.1038/s41375-019-0417-9
Autor:
Sunandan Saha, Wei-Chun Chang, Aaron E. Foster, Aruna Mahendravada, An Lu, Mariam Khalil, Kevin M. Slawin, Tsvetelina Pentcheva-Hoang, David M. Spencer, Nicholas P. Shinners, Joanne L. Shaw, My Linh T. Duong, David Torres, J. Henri Bayle, Matthew R. Collinson-Pautz, Jeannette Crisostomo, Eva Morschl, Tania Veliz Rodriguez
Publikováno v:
Molecular therapy : the journal of the American Society of Gene Therapy. 25(9)
Anti-tumor efficacy of T cells engineered to express chimeric antigen receptors (CARs) is dependent on their specificity, survival, and in vivo expansion following adoptive transfer. Toll-like receptor (TLR) and CD40 signaling in T cells can improve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfac6f110570e59ef012b52e5c6d1100
https://pubmed.ncbi.nlm.nih.gov/28830671
https://pubmed.ncbi.nlm.nih.gov/28830671
Autor:
Brittany R. Bitner, Thomas A. Kent, James M. Tour, Errol L. G. Samuel, My Linh T. Duong, Daniela C. Marcano
Publikováno v:
Trends in Biotechnology. 32:501-505
Oxidative stress reflects an excessive accumulation of reactive oxygen species (ROS) and is a hallmark of several acute and chronic human pathologies. Although many antioxidants have been investigated, most have demonstrated poor efficacy in clinical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c39f60d3330c14070c495f59ae831118
https://doi.org/10.1016/j.tibtech.2014.08.005
https://doi.org/10.1016/j.tibtech.2014.08.005
Autor:
Caimiao Wei, Wenbin Liu, Kelly K. Hunt, Khandan Keyomarsi, Yiling Lu, Gordon B. Mills, Hannah Wingate, My Linh T. Duong, Min Yi, Said Akli
Publikováno v:
PLoS Genetics, Vol 8, Iss 3, p e1002538 (2012)
Elastase-mediated cleavage of cyclin E generates low molecular weight cyclin E (LMW-E) isoforms exhibiting enhanced CDK2-associated kinase activity and resistance to inhibition by CDK inhibitors p21 and p27. Approximately 27% of breast cancers expres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fbcd5587fa345dc84c402f57864fdcc1
https://doi.org/10.1371/journal.pgen.1002538
https://doi.org/10.1371/journal.pgen.1002538