Zobrazeno 1 - 10
of 35
pro vyhledávání: '"My Andersson"'
Publikováno v:
Neurobiology of Disease, Vol 184, Iss , Pp 106234- (2023)
The advent of optogenetic tools has had a profound impact on modern neuroscience research, revolutionizing our understanding of the brain. These tools offer a remarkable ability to precisely manipulate specific groups of neurons with an unprecedented
Externí odkaz:
https://doaj.org/article/c0b1f57aec39486b83e55b6b643c1c54
Autor:
Matilda Ahl, Marie K. Taylor, Una Avdic, Anna Lundin, My Andersson, Åsa Amandusson, Eva Kumlien, Maria Compagno Strandberg, Christine T. Ekdahl
Publikováno v:
Heliyon, Vol 9, Iss 3, Pp e13938- (2023)
Inflammatory processes may provoke epileptic seizures and seizures may promote an immune reaction. Hence, the systemic immune reaction is a tempting diagnostic and prognostic marker in epilepsy. We explored the immune response before and after epilep
Externí odkaz:
https://doaj.org/article/a190e05cd4544358b83f24dae22d78f5
Autor:
Ana Gonzalez-Ramos, Eliška Waloschková, Apostolos Mikroulis, Zaal Kokaia, Johan Bengzon, Marco Ledri, My Andersson, Merab Kokaia
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-16 (2021)
Abstract Gamma-aminobutyric acid (GABA)-releasing interneurons modulate neuronal network activity in the brain by inhibiting other neurons. The alteration or absence of these cells disrupts the balance between excitatory and inhibitory processes, lea
Externí odkaz:
https://doaj.org/article/a2e6959621cd4950a88ad99f5f68143b
Autor:
Adriana Sanna, Bengt Phung, Shamik Mitra, Martin Lauss, Jiyeon Choi, Tongwu Zhang, Ching-Ni Njauw, Eugenia Cordero, Katja Harbst, Frida Rosengren, Rita Cabrita, Iva Johansson, Karolin Isaksson, Christian Ingvar, Ana Carneiro, Kevin Brown, Hensin Tsao, My Andersson, Kristian Pietras, Göran Jönsson
Publikováno v:
JCI Insight, Vol 7, Iss 19 (2022)
Cellular stress contributes to the capacity of melanoma cells to undergo phenotype switching into highly migratory and drug-tolerant dedifferentiated states. Such dedifferentiated melanoma cell states are marked by loss of melanocyte-specific gene ex
Externí odkaz:
https://doaj.org/article/37d81ad9a39246c69b971323fad1eabb
Autor:
Esbjörn Melin, Avtandil Nanobashvili, Una Avdic, Casper R. Gøtzsche, My Andersson, David P.D. Woldbye, Merab Kokaia
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 15, Iss , Pp 179-193 (2019)
Gene therapy has been suggested as a plausible novel approach to achieve seizure control in patients with focal epilepsy that do not adequately respond to pharmacological treatment. We investigated the seizure-suppressant potential of combinatorial n
Externí odkaz:
https://doaj.org/article/e42ffa9d891a4a0e901825ec3b32a469
Publikováno v:
Frontiers in Neurology, Vol 12 (2021)
Focal non-convulsive status epilepticus (fNCSE) is a neurological condition characterized by a prolonged seizure that may lead to the development of epilepsy. Emerging experimental evidence implicates neuronal death, microglial activation and alterat
Externí odkaz:
https://doaj.org/article/6aff1cd129714b44ae99cb1bb2b0086c
Autor:
Julia Adelöf, My Andersson, Michelle Porritt, Anne Petersen, Madeleine Zetterberg, John Wiseman, Malin Hernebring
Publikováno v:
BMC Neuroscience, Vol 19, Iss 1, Pp 1-15 (2018)
Abstract Background The proteasome system plays an important role in synaptic plasticity. Induction and maintenance of long term potentiation is directly dependent on selective targeting of proteins for proteasomal degradation. The 20S proteasome act
Externí odkaz:
https://doaj.org/article/4f116fb9727a4fcea7087870547ae017
Autor:
Eliška Waloschková, Ana Gonzalez-Ramos, Apostolos Mikroulis, Jan Kudláček, My Andersson, Marco Ledri, Merab Kokaia
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 24, p 13243 (2021)
Epilepsy is a complex disorder affecting the central nervous system and is characterised by spontaneously recurring seizures (SRSs). Epileptic patients undergo symptomatic pharmacological treatments, however, in 30% of cases, they are ineffective, mo
Externí odkaz:
https://doaj.org/article/d8762867ee8643b2bcce4fa6d9e743eb
Publikováno v:
Stem Cells International, Vol 2017 (2017)
Direct conversion of human somatic cells to induced neurons (iNs), using lineage-specific transcription factors has opened new opportunities for cell therapy in a number of neurological diseases, including epilepsy. In most severe cases of epilepsy,
Externí odkaz:
https://doaj.org/article/23404c6948804e0089cbbc60f812eb65
Autor:
Fredrik Berglind, Marco Ledri, Andreas Toft Sørensen, Litsa Nikitidou, Miriam Melis, Pascal Bielefeld, Deniz Kirik, Karl Deisseroth, My Andersson, Merab Kokaia
Publikováno v:
Neurobiology of Disease, Vol 65, Iss , Pp 133-141 (2014)
Synchronized activity is common during various physiological operations but can culminate in seizures and consequently in epilepsy in pathological hyperexcitable conditions in the brain. Many types of seizures are not possible to control and impose s
Externí odkaz:
https://doaj.org/article/3e8d81b144a640f789dab9c832dde6d7