Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Mwlod Ghareeb"'
Autor:
Yuan Chen, Christina Nadolny, Sangmin You, Mwlod Ghareeb, Liangran Guo, Ruitang Deng, Stephanie Shiffka, Ruchi Verma, Leila Valanejad, Fatemeh Akhlaghi
Publikováno v:
Molecular and Cellular Endocrinology. 470:127-141
Aldo-keto reductase family 1 member D1 (AKR1D1) is a Δ4-3-oxosteroid 5β-reductase required for bile acid synthesis and steroid hormone metabolism. Both bile acids and steroid hormones, especially glucocorticoids, play important roles in regulating
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5ea6e1fba734c01992b162a056acc8bc
https://doi.org/10.1016/j.mce.2017.10.005
https://doi.org/10.1016/j.mce.2017.10.005
Autor:
April N. Le, Lorenzo Leggio, Lisa A. Farinelli, Enoch Cobbina, Jenica D. Tapocik, Fatemeh Akhlaghi, Mwlod Ghareeb, Mehdi Farokhnia, Alexandra A. Dias, Markus Heilig, Mary R. Lee, Melanie L. Schwandt, Sofia Bouhlal
Publikováno v:
Molecular psychiatry
Rodent studies indicate that ghrelin receptor blockade reduces alcohol consumption. However, no ghrelin receptor blockers have been administered to heavy alcohol drinking individuals. Therefore, we evaluated the safety, tolerability, pharmacokinetic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7abdc4187be51af74e0fe7705beece83
https://doi.org/10.1038/s41380-018-0064-y
https://doi.org/10.1038/s41380-018-0064-y
Publikováno v:
Clinical Pharmacokinetics. 57:1199-1210
The objective of this study was to examine the association between tacrolimus concentration in oral fluids and in whole blood and to investigate the various factors that influence this relationship. Forty-six adult kidney transplant recipients were i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3e0d5b6fca6ba4a2413f8cdfa1ca326
https://doi.org/10.1007/s40262-017-0626-1
https://doi.org/10.1007/s40262-017-0626-1
Autor:
Fatemeh Akhlaghi, Mwlod Ghareeb
Publikováno v:
Journal of Chromatography B. 1038:136-141
Tacrolimus is a commonly used immunosuppressive agent in organ transplant recipients. Therapeutic drug monitoring (TDM) of tacrolimus is essential to adjust the dose and achieve optimal immunosuppression level. Routine TDM is practiced using whole bl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69cc5425f84b9c7fd52120c8cc6643a0
https://doi.org/10.1016/j.jchromb.2016.10.008
https://doi.org/10.1016/j.jchromb.2016.10.008
Publikováno v:
Analytical and Bioanalytical Chemistry. 407:5603-5613
PF-5190457 is a ghrelin receptor inverse agonist that is currently undergoing clinical development for the treatment of alcoholism. Our aim was to develop and validate a simple and sensitive assay for quantitative analysis of PF-5190457 in human or r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a31cc0632cce377ee6e3b455cb508c3
https://doi.org/10.1007/s00216-015-8730-2
https://doi.org/10.1007/s00216-015-8730-2
Autor:
Leila, Valanejad, Mwlod, Ghareeb, Stephanie, Shiffka, Christina, Nadolny, Yuan, Chen, Liangran, Guo, Ruchi, Verma, Sangmin, You, Fatemeh, Akhlaghi, Ruitang, Deng
Publikováno v:
Molecular and cellular endocrinology. 470
Aldo-keto reductase family 1 member D1 (AKR1D1) is a Δ(4)-3-oxosteroid 5β-reductase required for bile acid synthesis and steroid hormone metabolism. Both bile acids and steroid hormones, especially glucocorticoids, play important roles in regulatin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ef279685c951a0c109546331f23f5848
https://pubmed.ncbi.nlm.nih.gov/29024782
https://pubmed.ncbi.nlm.nih.gov/29024782
Autor:
Nils Tore Vethe, Anders Åsberg, Espen Molden, Ida Robertsen, Tone Granseth, Karsten Midtvedt, Morten Reier-Nilsen, Mwlod Ghareeb, Hallvard Holdaas, Fatemeh Akhlaghi
Publikováno v:
Transplantation. 97(12)
BACKGROUND Dyslipidemia is a risk factor for premature cardiovascular morbidity and mortality in renal transplant recipients (RTRs). Pharmacotherapy with mTOR inhibitors aggravates dyslipidemia, thus necessitating lipid-lowering therapy with fluvasta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6675016412dfa541c77be42d5151261
https://pubmed.ncbi.nlm.nih.gov/24521776
https://pubmed.ncbi.nlm.nih.gov/24521776