Zobrazeno 1 - 10 of 31 pro vyhledávání: '"Mwe Mwe Chao"'
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Akademický článek
A plea to provide best evidence in trials under sample-size restrictions: the example of pioglitazone to resolve leukoplakia and erythroplakia in Fanconi anemia patients
Autor: Florian Lasch, Kristina Weber, Mwe Mwe Chao, Armin Koch
Publikováno v: Orphanet Journal of Rare Diseases, Vol 12, Iss 1, Pp 1-6 (2017)
Abstract In planning a clinical trial for demonstrating the efficacy of pioglitazone to resolve leukoplakia and erythroplakia in Fanconi anemia patients we had to discuss the need for a randomized controlled trial particularly under sample-size restr
Externí odkaz: https://doaj.org/article/7065f8a170e0433699c385ae6919a833
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3
Mutational Spectrum of Fanconi Anemia Associated Myeloid Neoplasms
Autor: Marcin W. Wlodarski, Christian P. Kratz, Charlotte M. Niemeyer, Kathrin Thomay, Brigitte Schlegelberger, Mwe Mwe Chao, Victor B Pastor, Detlev Schindler, Gudrun Goehring
Publikováno v: Klinische Pädiatrie. 229:329-334
Individuals with Fanconi anemia (FA) have a high risk of developing myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML), yet the secondary somatic mutations lending to these malignancies remain to be further elucidated. We employed a next
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b7d80d1ebd043ec8aef116e73990bac
https://doi.org/10.1055/s-0043-117046
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5
Cancer Risk and Spectrum in Individuals with RASopathies
Autor: Mwe Mwe Chao, Christian P. Kratz, Martin Zenker
Publikováno v: Multidisciplinary Approach to Neurofibromatosis Type 1 ISBN: 9783319924496
The RAS/mitogen-activated protein kinase (MAPK) pathway is a highly conserved ubiquitous cellular signaling system that regulates critical cellular functions including proliferation, differentiation, survival, and apoptosis. Thus, dysregulation of th
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::50abca18428c1b0f8667d08f5ef8225b
https://doi.org/10.1007/978-3-319-92450-2_17
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6
A common ancestral DNMT3A-mutated preleukemic clone giving rise to AML and MDS in an adolescent girl
Autor: Irith Baumann, Felicitas Thol, Michael Xu, Mwe Mwe Chao, Gudrun Göhring, Marena R. Niewisch, Tim Ripperger, Kathrin Thomay, Dirk Reinhardt, Thomas Klingebiel, Gunnar Schmidt, Brigitte Schlegelberger, Nicole Wittner, Charlotte M. Niemeyer
Publikováno v: Leukemia & Lymphoma. 58:718-721
The gene encoding for DNA methyltransferase 3A (DNMT3A) is one of the most frequently mutated genes in hematologic malignancies. In myeloid neoplasia, DNMT3A mutations are most prevalent in acute m...
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe7249f3ef3bfca6d35faf9cbf583788
https://doi.org/10.1080/10428194.2016.1207765
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9
Outcomes of mismatched and unrelated donor hematopoietic stem cell transplantation in Fanconi anemia conditioned with chemotherapy only
Autor: Joern-Sven Kuehl, Christian P. Kratz, Irith Baumann, Heidemarie Neitzel, Mwe Mwe Chao, Detlev Schindler, Martin Zimmermann, Marion Nagy, H. von Bernuth, Jelena Rascon, Helmut Hanenberg, Charlotte M. Niemeyer, Wolfram Ebell, G. Strauss
Publikováno v: Annals of Hematology. 94:1311-1318
Fanconi anemia (FA) is a genomic instability syndrome associated with bone marrow failure, myelodysplastic syndrome (MDS), and/or acute myeloid leukemia (AML) requiring hematopoietic stem cell transplantation (HSCT) to restore normal hematopoiesis. A
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::160a4943aa9770c18ff648f811009327
https://doi.org/10.1007/s00277-015-2370-7
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10
A plea to provide best evidence in trials under sample-size restrictions: the example of pioglitazone to resolve leukoplakia and erythroplakia in Fanconi anemia patients
Autor: Kristina Weber, Florian Lasch, Armin Koch, Mwe Mwe Chao
Publikováno v: Orphanet Journal of Rare Diseases
Orphanet Journal of Rare Diseases, Vol 12, Iss 1, Pp 1-6 (2017)
62. Jahrestagung der Deutschen Gesellschaft für Medizinische Informatik, Biometrie und Epidemiologie e.V. (GMDS); 20170917-20170921; Oldenburg; DOCAbstr. 274 /20170829/
In planning a clinical trial for demonstrating the efficacy of pioglitazone to resolve leukoplakia and erythroplakia in Fanconi anemia patients we had to discuss the need for a randomized controlled trial particularly under sample-size restrictions a
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::915a4f19f15ce3ae78beb054b3fac002
https://pubmed.ncbi.nlm.nih.gov/28545482
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