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Publikováno v:
Bioorganicmedicinal chemistry letters. 75
Type I isopentenyl diphosphate isomerase is a metal-dependent enzyme that generates a tertiary carbocation intermediate during catalysis. This study describes an inhibitor (2-guanidinoethyl(dihydroxyphosphorylmethyl)phosphinate) of the isomerase that
Autor:
Chen Wei, Yang Jiajun, Hongtao Yang, Lin Shi, Wang Yuguang, Shanbo Cheng, Jiang Liyang, Muze Li, Wang Yanfeng
Publikováno v:
WMT