Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Muzaffer A. Kassab"'
Autor:
Jiaxu Wang, Zenglin Yuan, Yaqi Cui, Rong Xie, Guang Yang, Muzaffer A. Kassab, Mengxi Wang, Yinliang Ma, Chen Wu, Xiaochun Yu, Xiuhua Liu
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-9 (2018)
Tudor interacting repair regulator (TIRR) is a negative regulator of 53BP1 in DNA damage repair processes. Here the authors give mechanistic insights into how TIRR mediates suppression by solving the crystal structure of TIRR bound to the 53BP1 tande
Externí odkaz:
https://doaj.org/article/c49f7c9d4afb46d58974291e19e39bff
Autor:
Jiaxu Wang, Zenglin Yuan, Yaqi Cui, Rong Xie, Guang Yang, Muzaffer A. Kassab, Mengxi Wang, Yinliang Ma, Chen Wu, Xiaochun Yu, Xiuhua Liu
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-1 (2019)
The original version of this Article contained an error in the author affiliations. Xiaochun Yu was incorrectly associated with College of Life Sciences, Hebei University, Baoding 071000 Hebei, China.This has now been corrected in both the PDF and HT
Externí odkaz:
https://doaj.org/article/e304da6f4ddb4ec9829784224a4d7bf5
Publikováno v:
BMC Biology, Vol 22, Iss 1, Pp 1-19 (2024)
Abstract Background RNA–DNA hybrids or R-loops are associated with deleterious genomic instability and protective immunoglobulin class switch recombination (CSR). However, the underlying phenomenon regulating the two contrasting functions of R-loop
Externí odkaz:
https://doaj.org/article/7b15e100421340b5a3a8e3d42ac8fe09
Autor:
Xin Li, Liwei An, Yucui Jin, Jun Gui, Weitao Lin, Zhenke Wen, Muzaffer Ahmad Kassab, Jie Chen
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 13 (2023)
Externí odkaz:
https://doaj.org/article/68a8accaa395424387151dbc24d25bf6
Autor:
Muzaffer Ahmad Kassab, Madeeha Mudassir, Anand Singh, Muthuraman N, Mohita Bhagat, Jayanth Kumar Palanichamy, Pradeep Ramalingam, Kunzang Chosdol, Subrata Sinha, Parthaprasad Chattopadhyay
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0128416 (2015)
Recently various studies have demonstrated the role of promoter associated non-coding RNAs (pRNA) in dsRNA induced transcriptional gene silencing and activation. However the exact mechanistic details of these processes with respect to the orientation
Externí odkaz:
https://doaj.org/article/a1204911a5794827890c80533535b433
Autor:
Muzaffer Ahmad Kassab, Xiaochun Yu
Publikováno v:
DNA Repair (Amst)
Poly(ADP-ribosyl)ation (PARylation) is a reversible post-translational modification regulating various biological pathways including DNA damage repair (DDR). Rapid turnover of PARylation is critically important for an optimal DNA damage response and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9e6ce3d9009e88cb951c244f77aa181
https://doi.org/10.1016/j.dnarep.2019.02.002
https://doi.org/10.1016/j.dnarep.2019.02.002
Autor:
Xiuhua Liu, Rong Xie, Xiaochun Yu, Guang Yang, Jiaxu Wang, Yinliang Ma, Chen Wu, Mengxi Wang, Zenglin Yuan, Muzaffer Ahmad Kassab, Yaqi Cui
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-9 (2018)
53BP1 performs essential functions in DNA double-strand break (DSB) repair and it was recently reported that Tudor interacting repair regulator (TIRR) negatively regulates 53BP1 during DSB repair. Here, we present the crystal structure of the 53BP1 t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4cbfa6bbc312650e998be60c50d5285
https://doaj.org/article/c49f7c9d4afb46d58974291e19e39bff
https://doaj.org/article/c49f7c9d4afb46d58974291e19e39bff
Autor:
Shih-Hsun Chen, Nils G. Walter, Muzaffer Ahmad Kassab, Guang Yang, Chao Liu, J. Damon Hoff, Xiaochun Yu
Publikováno v:
Nucleic Acids Research
DNA double-strand breaks (DSBs) are fatal DNA lesions and activate a rapid DNA damage response. However, the earliest stage of DSB sensing remains elusive. Here, we report that PARP1 and the Ku70/80 complex localize to DNA lesions considerably earlie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d05701efeeb3d2307f5e13a29524c96a
http://europepmc.org/articles/PMC5909444
http://europepmc.org/articles/PMC5909444
Autor:
Yonghao Yu, Chunjing Bian, Muzaffer Ahmad Kassab, Xiuhua Liu, Qian Chen, Xin Wang, Xiaochun Yu
Publikováno v:
EMBO J
Optimal DNA damage response is associated with ADP-ribosylation of histones. However, the underlying molecular mechanism of DNA damage-induced histone ADP-ribosylation remains elusive. Herein, using unbiased mass spectrometry, we identify that glutam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74e8a0a9ffc2827f21389edcc7d5c47d
https://pubmed.ncbi.nlm.nih.gov/33264433
https://pubmed.ncbi.nlm.nih.gov/33264433
Publikováno v:
Cell & Bioscience
Cell & Bioscience, Vol 10, Iss 1, Pp 1-9 (2020)
Cell & Bioscience, Vol 10, Iss 1, Pp 1-9 (2020)
Poly(ADP-ribosyl)ation (PARylation) mediated by poly ADP-ribose polymerases (PARPs) plays a key role in DNA damage repair. Suppression of PARylation by PARP inhibitors impairs DNA damage repair and induces apoptosis of tumor cells with repair defects
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20bc8b4c63893bea2bc14bdd872a22a5
https://pubmed.ncbi.nlm.nih.gov/32010441
https://pubmed.ncbi.nlm.nih.gov/32010441