Zobrazeno 1 - 10
of 108
pro vyhledávání: '"Muzafar A. Macha"'
Autor:
Ravi Chauhan, Lakshay Malhotra, Ashna Gupta, Gunjan Dagar, Mohini Mendiratta, Tariq Masoodi, Sheema Hashem, Sara Al Marzooqi, Dayasagar Das, Shahab Uddin, Abdul Samath Ethayathulla, Muzafar A. Macha, Ammira Al-Shabeeb Akil, Ranjit Kumar Sahoo, Ekta Rai, Ajaz A. Bhat, Mayank Singh
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract Cervical cancer is still the leading cause of cancer mortality worldwide even after introduction of vaccine against Human papillomavirus (HPV), due to low vaccine coverage, especially in the developing world. Cervical cancer is primarily tre
Externí odkaz:
https://doaj.org/article/3a46cb6c43a04b3a9594e8fbe52d8711
Autor:
Gunjan Dagar, Ashna Gupta, Abhishek Shankar, Ravi Chauhan, Muzafar A. Macha, Ajaz A. Bhat, Dayasagar Das, Rajeev Goyal, Sandeep Bhoriwal, Raj K. Pandita, Chandra Prakash Prasad, Partha S. Sarkar, Tej K. Pandita, Mayank Singh
Publikováno v:
Frontiers in Molecular Biosciences, Vol 11 (2024)
Radiotherapy (RT) and immunotherapy (IT) are the powerful tools for cancer treatment which act through the stimulation of immune response, and evidence suggest that combinatorial actions of these therapies may augment each other’s beneficial effect
Externí odkaz:
https://doaj.org/article/5798c3e6919e4395bbacae37a206a957
Autor:
Inamu Rashid Khan, Hana Q. Sadida, Sheema Hashem, Mayank Singh, Muzafar A. Macha, Ammira S. Al-Shabeeb Akil, Ibraq Khurshid, Ajaz A. Bhat
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 176, Iss , Pp 116873- (2024)
Esophageal cancer (EC) is significantly influenced by the tumor microenvironment (TME) and altered signaling pathways. Downregulating these pathways in EC is essential for suppressing tumor development, preventing metastasis, and enhancing therapeuti
Externí odkaz:
https://doaj.org/article/b8fcaaa6fc5b49d5a6662b518cee36e3
Autor:
Mudasir A. Kumar, Sadaf K. Baba, Hana Q. Sadida, Sara Al. Marzooqi, Jayakumar Jerobin, Faisal H. Altemani, Naseh Algehainy, Mohammad A. Alanazi, Abdul-Badi Abou-Samra, Rakesh Kumar, Ammira S. Al-Shabeeb Akil, Muzafar A. Macha, Rashid Mir, Ajaz A. Bhat
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 9, Iss 1, Pp 1-41 (2024)
Abstract Extracellular vesicles (EVs) are nano-sized, membranous structures secreted into the extracellular space. They exhibit diverse sizes, contents, and surface markers and are ubiquitously released from cells under normal and pathological condit
Externí odkaz:
https://doaj.org/article/1a35b39ef93445ee97264d01aaeca7e3
Autor:
Syed Wajid Aalam, Abdul Basit Ahanger, Tariq A. Masoodi, Ajaz A. Bhat, Ammira S. Al-Shabeeb Akil, Meraj Alam Khan, Assif Assad, Muzafar A. Macha, Muzafar Rasool Bhat
Publikováno v:
Frontiers in Molecular Biosciences, Vol 11 (2024)
Esophageal cancer (EC) remains a significant health challenge globally, with increasing incidence and high mortality rates. Despite advances in treatment, there remains a need for improved diagnostic methods and understanding of disease progression.
Externí odkaz:
https://doaj.org/article/b5c4c37d64054dd0bf08f51a5f258005
Autor:
Gh. Rasool Bhat, Rajeshwer Singh Jamwal, Itty Sethi, Amrita Bhat, Ruchi Shah, Sonali Verma, Minerva Sharma, Hana Q. Sadida, Sara K. Al-Marzooqi, Tariq Masoodi, Sameer Mirza, Mohammad Haris, Muzafar A. Macha, Ammira S. Alshabeeb Akil, Ajaz A. Bhat, Rakesh Kumar
Publikováno v:
BMC Cancer, Vol 23, Iss 1, Pp 1-10 (2023)
Abstract Background Telomeres are repetitive DNA sequences located at the ends of chromosomes, playing a vital role in maintaining chromosomal integrity and stability. Dysregulation of telomeres has been implicated in the development of various cance
Externí odkaz:
https://doaj.org/article/08c73e39f041413bb3a634d17dadb993
Autor:
Hana Q. Sadida, Alanoud Abdulla, Sara Al Marzooqi, Sheema Hashem, Muzafar A. Macha, Ammira S. Al-Shabeeb Akil, Ajaz A. Bhat
Publikováno v:
Translational Oncology, Vol 39, Iss , Pp 101821- (2024)
Cancer heterogeneity and drug resistance remain pivotal obstacles in effective cancer treatment and management. One major contributor to these challenges is epigenetic modifications - gene regulation that does not involve changes to the DNA sequence
Externí odkaz:
https://doaj.org/article/2bb1b351fffd41b4bdb969179d8d4c17
Autor:
Gunjan Dagar, Ashna Gupta, Tariq Masoodi, Sabah Nisar, Maysaloun Merhi, Sheema Hashem, Ravi Chauhan, Manisha Dagar, Sameer Mirza, Puneet Bagga, Rakesh Kumar, Ammira S. Al-Shabeeb Akil, Muzafar A. Macha, Mohammad Haris, Shahab Uddin, Mayank Singh, Ajaz A. Bhat
Publikováno v:
Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-36 (2023)
Abstract Traditional cancer treatments use nonspecific drugs and monoclonal antibodies to target tumor cells. Chimeric antigen receptor (CAR)-T cell therapy, however, leverages the immune system's T-cells to recognize and attack tumor cells. T-cells
Externí odkaz:
https://doaj.org/article/849387ccca01487e82e56bc5e5cb5949
Autor:
Ravi Chauhan, Ashna Gupta, Lakshay Malhotra, Ajaz A. Bhat, Raj K. Pandita, Tariq Masoodi, Gunjan Dagar, Hana Q. Sadida, Sara K. Al-Marzooqi, Atul Batra, Sameer Bakhshi, Mehar Chand Sharma, Pranay Tanwar, Shah Alam Khan, Ethayathulla Abdul Samath, Shahab Uddin, Ammira S. Al-Shabeeb Akil, Mohammad Haris, Muzafar A. Macha, Tej K. Pandita, Mayank Singh
Publikováno v:
Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-24 (2023)
Abstract Background Osteosarcoma is a type of bone cancer that predominantly affects young individuals, including children and adolescents. The disease progresses through heterogeneous genetic alterations, and patients often develop pulmonary metasta
Externí odkaz:
https://doaj.org/article/785bc983a588478e95e773960f35d401
Autor:
Muzamil Farooq, Gh. Rasool Bhat, Syed Besina, Natasha Thakur, Sheikh Zahoor, Rafiq A. Rather, Ifra Mushtaq, Sadaf Dar, Bilal Rah, Ajaz A. Bhat, Muzafar A. Macha, Dil Afroze
Publikováno v:
Translational Medicine Communications, Vol 8, Iss 1, Pp 1-13 (2023)
Abstract Hypoxic zones exist in solid tumors, where oxygen levels are significantly lower than in normal tissues. Hypoxia makes chemo-radiation therapeutics less effective and renders the metastatic potential more favorable. Emerging research has fou
Externí odkaz:
https://doaj.org/article/a96a3fe06d42481dae75059344b8d367