Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Muyao Guo"'
Publikováno v:
Autoimmunity, Vol 56, Iss 1 (2023)
Dermatomyositis (DM) is an autoimmune disease that primarily affects the skin and skeletal muscle. Virus infection and type I interferon-related signaling pathways play an important role in the pathogenesis of dermatomyositis. In this study, we found
Externí odkaz:
https://doaj.org/article/34e3ddff52c14e1b98d00025c8d77e5a
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 13, Iss 5, Pp 2456-2472 (2022)
Abstract Objectives Idiopathic inflammatory myopathies (IIM) are a class of autoimmune diseases with high heterogeneity that can be divided into different subtypes based on clinical manifestations and myositis‐specific autoantibodies (MSAs). Howeve
Externí odkaz:
https://doaj.org/article/a5713eaa0c1c44a9902a4c79f4bdb6a6
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
The pathogenesis of systemic lupus erythematosus (SLE) is related to immune homeostasis imbalance. Epigenetic mechanisms have played a significant role in breaking immune tolerance. Enhancer of zeste homolog 2 (EZH2), the specific methylation transfe
Externí odkaz:
https://doaj.org/article/c898f3675ef1429ab38a0ba9bcb441d1
Autor:
Christopher D. Scharer, Benjamin G. Barwick, Muyao Guo, Alexander P. R. Bally, Jeremy M. Boss
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
During B cell differentiation, the role of different genomic loci in transcriptional and epigenetic regulation in vivo is not well defined. Here the authors use an in vivo B cell differentiation model to map cellular division-dependent cis-regulatory
Externí odkaz:
https://doaj.org/article/ce454525ef924494b954d29152418aee
Publikováno v:
Genomics, Proteomics & Bioinformatics, Vol 13, Iss 4, Pp 234-241 (2015)
Systemic sclerosis (SSc) is a multisystem fibrotic and autoimmune disease. Both genetic and epigenetic elements mediate SSc pathophysiology. This review summarizes the role of one epigenetic element, known as microRNAs (miRNAs), involved in different
Externí odkaz:
https://doaj.org/article/0455ab190e2a4891be0113e45289f4f9
Publikováno v:
Lupus. 32:231-238
Objectives The aim of this study is to explore the association of podocyte injury with clinical features and outcomes in mesangial proliferative (Class II) lupus nephritis (LN). Methods We conducted a retrospective and clinicopathologic analysis with
Autor:
Muyao Guo, Di Liu, Yu Jiang, Weilin Chen, Lijuan Zhao, Ding Bao, Yisha Li, Jörg H.W. Distler, Honglin Zhu
Publikováno v:
Metabolism. 144:155587
Autor:
Yiying Yang, Muyuan Li, Yaxi Zhu, Ke Liu, Meidong Liu, Yanjuan Liu, Ganqian Zhu, Hui Luo, Xiaoxia Zuo, Huali Zhang, Muyao Guo
Publikováno v:
International Immunopharmacology. 119:110155
Autor:
Muyao Guo, Alexander P. R. Bally, Christopher D. Scharer, Jeremy M. Boss, Benjamin G. Barwick
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
Nature Communications
Nature Communications
The genomic loci associated with B cell differentiation that are subject to transcriptional and epigenetic regulation in vivo are not well defined, leaving a gap in our understanding of the development of humoral immune responses. Here, using an in v