Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Mutsumi Miyamoto"'
Autor:
Phillip Barley, Timothy M. Crowder, Dale J. Christensen, Matt Cowlen, Matthew P. Walker, Mutsumi Miyamoto
Publikováno v:
Inhalation Toxicology. 29:356-365
ENaC inhibition has long been an attractive therapeutic target for the treatment of cystic fibrosis. However, previous attempts at developing ENaC inhibitors have been unsuccessful due to complications arising from systemic circulation of the compoun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5701cd434eeb03a20c4746d952532913
https://doi.org/10.1080/08958378.2017.1366602
https://doi.org/10.1080/08958378.2017.1366602
Autor:
Mutsumi Miyamoto, Johan Verbeeck, Gareth Thomas, Michael K. Pugsley, Jennifer L. Ingram-Ross, Birgit Verstynen, J. Sheehan, Aidan K. Curran, Eric J. de Waal
Publikováno v:
Journal of Pharmacological and Toxicological Methods. 66:114-124
Introduction This study was designed to provide a comprehensive nonclinical respiratory safety pharmacology assessment using respiratory inductance plethysmography (RIP) concomitant with a standard cardiovascular (CV) safety assessment in non-human p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::549b668149659d875c5c5e0f4fb095a4
https://doi.org/10.1016/j.vascn.2012.04.002
https://doi.org/10.1016/j.vascn.2012.04.002
Publikováno v:
Journal of Veterinary Internal Medicine. 21:445-450
There have been few trials in which dogs with mitral regurgitation (MR) have been treated with various cardioactive drugs to determine effects on left ventricular (LV) function.Four classes of cardiovascular drugs may improve LV function in dogs with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2c158e4be6d0bef34b82351979090cb
https://doi.org/10.1111/j.1939-1676.2007.tb02988.x
https://doi.org/10.1111/j.1939-1676.2007.tb02988.x
Publikováno v:
American Journal of Veterinary Research. 61:57-60
Objective—To determine acute cardiovascular effects and pharmacokinetics of carvedilol in healthy dogs. Animals—14 mature healthy Beagles. Procedure—12 dogs were anesthetized with morphine and α-chloralose. Catheters were placed in the aorta,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db0bf501da2dab479963415d7ce2615b
https://doi.org/10.2460/ajvr.2000.61.57
https://doi.org/10.2460/ajvr.2000.61.57
Publikováno v:
The FASEB Journal. 20
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::757e1038e3a0e52cac470773af841f68
https://doi.org/10.1096/fasebj.20.4.a674-b
https://doi.org/10.1096/fasebj.20.4.a674-b
Publikováno v:
Journal of veterinary internal medicine. 15(6)
Atrial fibrillation (AF) is one of the most important arrhythmias of dogs. In a previous study, we determined the dosage of intravenously administered diltiazem necessary to reduce ventricular response (VR), cardiac output (CO), and mean systemic art
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9bfd605213e81be91266dfa9e7d6927a
https://pubmed.ncbi.nlm.nih.gov/11817061
https://pubmed.ncbi.nlm.nih.gov/11817061
Publikováno v:
Journal of Pharmacological and Toxicological Methods. 70:334
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4021f8dbbd413ff6cd779172d0d145cd
https://doi.org/10.1016/j.vascn.2014.03.087
https://doi.org/10.1016/j.vascn.2014.03.087
Autor:
J. Domanski, T. Ziegelhoffer, C. Rowe, Mutsumi Miyamoto, Sylvie Gosselin, G.C. Karantabias, C.M. Kelly, S. Vessie, T. Ramani, S. Cracknell
Publikováno v:
Journal of Pharmacological and Toxicological Methods. 60:252-253
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0aecc43156ac5979643215b50ea8cb1d
https://doi.org/10.1016/j.vascn.2009.04.175
https://doi.org/10.1016/j.vascn.2009.04.175
Publikováno v:
Journal of veterinary internal medicine. 13(5)
We investigated the effects of graded dosages of magnesium given i.v. to anesthetized dogs on blood pressure, cardiac output, and electrophysiology. Magnesium was infused at 0.12 mEq/kg/minute until ventricular fibrillation occurred naturally or was
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1af801d43b184518ac1a25844eb08e67
https://pubmed.ncbi.nlm.nih.gov/10499734
https://pubmed.ncbi.nlm.nih.gov/10499734
Publikováno v:
Journal of Pharmacological and Toxicological Methods. 68:e12
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fe4672f5108c51b7c82adc2eb0bddcc0
https://doi.org/10.1016/j.vascn.2013.01.051
https://doi.org/10.1016/j.vascn.2013.01.051