A microfluidic transistor for automatic control of liquids.

Autor: Gopinathan KA; BioMEMS Resource Center, Center for Engineering in Medicine and Surgical Services, Massachusetts General Hospital, Boston, MA, USA., Mishra A; BioMEMS Resource Center, Center for Engineering in Medicine and Surgical Services, Massachusetts General Hospital, Boston, MA, USA.; Cancer Center, Massachusetts General Hospital, Boston, MA, USA.; Department of Surgery, Massachusetts General Hospital, Boston, MA, USA., Mutlu BR; BioMEMS Resource Center, Center for Engineering in Medicine and Surgical Services, Massachusetts General Hospital, Boston, MA, USA.; Department of Surgery, Massachusetts General Hospital, Boston, MA, USA., Edd JF; BioMEMS Resource Center, Center for Engineering in Medicine and Surgical Services, Massachusetts General Hospital, Boston, MA, USA.; Cancer Center, Massachusetts General Hospital, Boston, MA, USA., Toner M; BioMEMS Resource Center, Center for Engineering in Medicine and Surgical Services, Massachusetts General Hospital, Boston, MA, USA. mtoner@mgh.harvard.edu.; Department of Surgery, Massachusetts General Hospital, Boston, MA, USA. mtoner@mgh.harvard.edu.; Shriners Children's, Boston, MA, USA. mtoner@mgh.harvard.edu.

Publikováno v: Nature [Nature] 2023 Oct; Vol. 622 (7984), pp. 735-741. Date of Electronic Publication: 2023 Oct 25.

Ultrahigh-throughput magnetic sorting of large blood volumes for epitope-agnostic isolation of circulating tumor cells.

Autor: Mishra A; BioMEMS Resource Center, Charlestown, MA 02129.; Center for Engineering in Medicine and Surgery, Massachusetts General Hospital, Boston, MA 02114.; Cancer Center, Massachusetts General Hospital, Boston, MA 02114.; Harvard Medical School, Boston, MA 02115., Dubash TD; Cancer Center, Massachusetts General Hospital, Boston, MA 02114.; Harvard Medical School, Boston, MA 02115., Edd JF; BioMEMS Resource Center, Charlestown, MA 02129.; Center for Engineering in Medicine and Surgery, Massachusetts General Hospital, Boston, MA 02114.; Cancer Center, Massachusetts General Hospital, Boston, MA 02114., Jewett MK; BioMEMS Resource Center, Charlestown, MA 02129.; Center for Engineering in Medicine and Surgery, Massachusetts General Hospital, Boston, MA 02114.; Cancer Center, Massachusetts General Hospital, Boston, MA 02114., Garre SG; BioMEMS Resource Center, Charlestown, MA 02129.; Center for Engineering in Medicine and Surgery, Massachusetts General Hospital, Boston, MA 02114.; Cancer Center, Massachusetts General Hospital, Boston, MA 02114., Karabacak NM; BioMEMS Resource Center, Charlestown, MA 02129.; Center for Engineering in Medicine and Surgery, Massachusetts General Hospital, Boston, MA 02114.; Shriners Hospitals for Children, Boston, MA 02114., Rabe DC; BioMEMS Resource Center, Charlestown, MA 02129.; Center for Engineering in Medicine and Surgery, Massachusetts General Hospital, Boston, MA 02114.; Cancer Center, Massachusetts General Hospital, Boston, MA 02114.; Harvard Medical School, Boston, MA 02115., Mutlu BR; BioMEMS Resource Center, Charlestown, MA 02129.; Center for Engineering in Medicine and Surgery, Massachusetts General Hospital, Boston, MA 02114.; Harvard Medical School, Boston, MA 02115., Walsh JR; BioMEMS Resource Center, Charlestown, MA 02129.; Center for Engineering in Medicine and Surgery, Massachusetts General Hospital, Boston, MA 02114.; Cancer Center, Massachusetts General Hospital, Boston, MA 02114., Kapur R; MicroMedicine, Inc., Waltham, MA 02451., Stott SL; BioMEMS Resource Center, Charlestown, MA 02129.; Center for Engineering in Medicine and Surgery, Massachusetts General Hospital, Boston, MA 02114.; Cancer Center, Massachusetts General Hospital, Boston, MA 02114.; Harvard Medical School, Boston, MA 02115., Maheswaran S; Cancer Center, Massachusetts General Hospital, Boston, MA 02114.; Harvard Medical School, Boston, MA 02115., Haber DA; Cancer Center, Massachusetts General Hospital, Boston, MA 02114; dhaber@mgh.harvard.edu mtoner@hms.harvard.edu.; Harvard Medical School, Boston, MA 02115.; Howard Hughes Medical Institute, Bethesda, MD 20815., Toner M; BioMEMS Resource Center, Charlestown, MA 02129; dhaber@mgh.harvard.edu mtoner@hms.harvard.edu.; Center for Engineering in Medicine and Surgery, Massachusetts General Hospital, Boston, MA 02114.; Harvard Medical School, Boston, MA 02115.; Shriners Hospitals for Children, Boston, MA 02114.

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2020 Jul 21; Vol. 117 (29), pp. 16839-16847. Date of Electronic Publication: 2020 Jul 08.

Microfluidic concentration and separation of circulating tumor cell clusters from large blood volumes.

Autor: Edd JF; BioMEMS Resource Center, Center for Engineering in Medicine and Surgical Services, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts 02114, USA. mehmet_toner@hms.harvard.edu and Cancer Center, Massachusetts General Hospital, Boston, Massachusetts 02114, USA., Mishra A; BioMEMS Resource Center, Center for Engineering in Medicine and Surgical Services, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts 02114, USA. mehmet_toner@hms.harvard.edu., Dubash TD; Cancer Center, Massachusetts General Hospital, Boston, Massachusetts 02114, USA and Harvard Medical School, Boston, MA 02115, USA., Herrera S; BioMEMS Resource Center, Center for Engineering in Medicine and Surgical Services, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts 02114, USA. mehmet_toner@hms.harvard.edu., Mohammad R; BioMEMS Resource Center, Center for Engineering in Medicine and Surgical Services, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts 02114, USA. mehmet_toner@hms.harvard.edu., Williams EK; BioMEMS Resource Center, Center for Engineering in Medicine and Surgical Services, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts 02114, USA. mehmet_toner@hms.harvard.edu., Hong X; Cancer Center, Massachusetts General Hospital, Boston, Massachusetts 02114, USA., Mutlu BR; BioMEMS Resource Center, Center for Engineering in Medicine and Surgical Services, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts 02114, USA. mehmet_toner@hms.harvard.edu., Walsh JR; BioMEMS Resource Center, Center for Engineering in Medicine and Surgical Services, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts 02114, USA. mehmet_toner@hms.harvard.edu and Cancer Center, Massachusetts General Hospital, Boston, Massachusetts 02114, USA., Machado de Carvalho F; Cancer Center, Massachusetts General Hospital, Boston, Massachusetts 02114, USA., Aldikacti B; BioMEMS Resource Center, Center for Engineering in Medicine and Surgical Services, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts 02114, USA. mehmet_toner@hms.harvard.edu and Cancer Center, Massachusetts General Hospital, Boston, Massachusetts 02114, USA., Nieman LT; Cancer Center, Massachusetts General Hospital, Boston, Massachusetts 02114, USA., Stott SL; BioMEMS Resource Center, Center for Engineering in Medicine and Surgical Services, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts 02114, USA. mehmet_toner@hms.harvard.edu and Cancer Center, Massachusetts General Hospital, Boston, Massachusetts 02114, USA and Harvard Medical School, Boston, MA 02115, USA., Kapur R; MicroMedicine, Inc., Waltham, MA 02451, USA., Maheswaran S; Cancer Center, Massachusetts General Hospital, Boston, Massachusetts 02114, USA and Harvard Medical School, Boston, MA 02115, USA., Haber DA; Cancer Center, Massachusetts General Hospital, Boston, Massachusetts 02114, USA and Harvard Medical School, Boston, MA 02115, USA and Howard Hughes Medical Institute, Bethesda, MD 20815, USA., Toner M; BioMEMS Resource Center, Center for Engineering in Medicine and Surgical Services, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts 02114, USA. mehmet_toner@hms.harvard.edu and Shriners Hospitals for Children, Boston, Massachusetts 02114, USA.

Publikováno v: Lab on a chip [Lab Chip] 2020 Feb 07; Vol. 20 (3), pp. 558-567. Date of Electronic Publication: 2020 Jan 14.

Oscillatory inertial focusing in infinite microchannels.

Autor: Mutlu BR; BioMEMS Resource Center, Center for Engineering in Medicine and Surgical Services, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114., Edd JF; BioMEMS Resource Center, Center for Engineering in Medicine and Surgical Services, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114.; Massachusetts General Hospital Cancer Center, Harvard Medical School, Boston, MA 02114., Toner M; BioMEMS Resource Center, Center for Engineering in Medicine and Surgical Services, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114; mtoner@hms.harvard.edu.; Shriners Hospitals for Children, Boston, MA 02114.

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2018 Jul 24; Vol. 115 (30), pp. 7682-7687. Date of Electronic Publication: 2018 Jul 10.

Non-equilibrium Inertial Separation Array for High-throughput, Large-volume Blood Fractionation.

Autor: Mutlu BR; BioMEMS Resource Center, Center for Engineering in Medicine and Surgical Services, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, 02114, USA., Smith KC; MicroMedicine Inc., Watertown, Massachusetts, 02472, USA., Edd JF; BioMEMS Resource Center, Center for Engineering in Medicine and Surgical Services, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, 02114, USA.; Massachusetts General Hospital Cancer Center and Harvard Medical School, Boston, Massachusetts, 02114, USA., Nadar P; MicroMedicine Inc., Watertown, Massachusetts, 02472, USA., Dlamini M; BioMEMS Resource Center, Center for Engineering in Medicine and Surgical Services, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, 02114, USA., Kapur R; BioMEMS Resource Center, Center for Engineering in Medicine and Surgical Services, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, 02114, USA.; Massachusetts General Hospital Cancer Center and Harvard Medical School, Boston, Massachusetts, 02114, USA.; MicroMedicine Inc., Watertown, Massachusetts, 02472, USA., Toner M; BioMEMS Resource Center, Center for Engineering in Medicine and Surgical Services, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, 02114, USA. mtoner@hms.harvard.edu.; Shriners Hospital for Children, Boston, Massachusetts, 02114, USA. mtoner@hms.harvard.edu.

Publikováno v: Scientific reports [Sci Rep] 2017 Aug 30; Vol. 7 (1), pp. 9915. Date of Electronic Publication: 2017 Aug 30.