Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Muthukumar G. Sankar"'
Autor:
Kamal Kumar, Carsten Strohmann, Axel Pahl, Stefan Zimmermann, Slava Ziegler, Felix Otte, Mohammad Akbarzadeh, Sonja Sievers, Muthukumar G. Sankar
Publikováno v:
Chemistry (Weinheim an Der Bergstrasse, Germany)
A “branching–folding” synthetic strategy that affords a range of diverse cyclic benzo‐sulfonamide scaffolds is presented. Whereas different annulation reactions on common ketimine substrates build the branching phase of the scaffold synthesis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4c4dd665d775fc338957865ef92a576
https://doi.org/10.1002/chem.201904175
https://doi.org/10.1002/chem.201904175
Autor:
Muthukumar G. Sankar, Carsten Strohmann, Kathrin Wittstein, Tuyen Thi Ngoc Tran, Jonathan O. Bauer, S. Roy, Kamal Kumar, Slava Ziegler
Publikováno v:
ChemistryOpen
Complexity‐generating chemical transformations that afford novel molecular scaffolds enriched in sp 3 character are highly desired. Here, we present a highly stereoselective scaffold diversity synthesis approach that utilizes cascade double‐annul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82c41f7c29959d25ca4591a1d85195b0
https://doi.org/10.1002/open.201800025
https://doi.org/10.1002/open.201800025
Publikováno v:
Angewandte Chemie. 128:7712-7732
Die Gerustdiversitat ist ein entscheidendes Merkmal von Verbindungskollektionen, das einen grosen Einfluss auf deren Erfolg beim biologischen Screening hat. Die Synthese hochkomplexer und verschiedenartiger Geruste, die beispielsweise auf Naturstoffe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d39199c577b4f447a797275f19e3e0fe
https://doi.org/10.1002/ange.201508818
https://doi.org/10.1002/ange.201508818
Publikováno v:
RSC Advances. 6:56537-56543
The zwitterionic 1,3-dipoles generated by the addition of a bifunctional L-isoleucine derived N-acylaminophosphine to allenic esters as well as ketones were successfully trapped with isatin derived ketimines in a [3 + 2]-annulation reaction to delive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3d5eb6ca0301ed6bf4eb0fcec04f1f79
https://doi.org/10.1039/c6ra12387b
https://doi.org/10.1039/c6ra12387b
Publikováno v:
ChemInform. 47
Catalytic addition of chiral phosphine, that is, (R)- or (S)-SITCP, to an α-substituted allene ester generated a zwitterionic dipole. Under optimized reaction conditions, this dipole could engage isatine-derived N-Boc-ketimines in a novel mode of [3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::432f8efbb3fb814b8227065bed1cc67f
https://doi.org/10.1002/chin.201650081
https://doi.org/10.1002/chin.201650081
Publikováno v:
ChemInform. 47
affording a wide range of dihydropyrrolyl spirooxindoles with excellent enantioselectivities
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5c8ac1da04bc2bf09343e5d38497c623
https://doi.org/10.1002/chin.201643099
https://doi.org/10.1002/chin.201643099
Publikováno v:
ChemInform. 47
Scaffold diversity is a crucial feature of compound collections that has a huge impact on their success in biological screenings. The synthesis of highly complex and diverse scaffolds, which could be based on natural products, for example, is an ardu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8bb332bcb91578d00edac547219b78ad
https://doi.org/10.1002/chin.201635174
https://doi.org/10.1002/chin.201635174
Autor:
Vivek Khedkar, Kathrin Wittstein, Baburaj Baskar, Muthukumar G. Sankar, Markus Schürmann, Kamal Kumar
Publikováno v:
Organic Letters; Vol 14
Organic Letters
Organic Letters
A cascade double-annulation strategy employing diverse pairs of zwitterions with 3-formylchromones is presented that provides stereoselective access to complex tetracyclic benzopyrones. Different zwitterions incorporated different rings that include
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::279ed8b8247004cea1865bac714fd973
Publikováno v:
European Journal of Organic Chemistry. 2011:6980-6988
A diversity-oriented synthesis is described for functionalized chiral building blocks (i.e., 7, 9, 10, 16, and 17) and the biologically active iminosugar, fucosidase inhibitor (2S,3R,4R,5R)-2-(hydroxymethyl)-5- methylpyrrolidine-3,4-diol (22), starti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a944e18c53f40122c31ecbb17ad7db2c
https://doi.org/10.1002/ejoc.201100968
https://doi.org/10.1002/ejoc.201100968
Publikováno v:
Angewandte Chemie (International ed. in English). 55(27)
Scaffold diversity is a crucial feature of compound collections that has a huge impact on their success in biological screenings. The synthesis of highly complex and diverse scaffolds, which could be based on natural products, for example, is an ardu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86785f7fe355d4aaf8c5411ea2610be3
https://pubmed.ncbi.nlm.nih.gov/27187638
https://pubmed.ncbi.nlm.nih.gov/27187638