Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Muthukaman, Nagarajan"'
Autor:
Yves Pommier, Mark Cushman, Andrew Morrell, Muthukaman Nagarajan, Lyuba Varticovski, Ana I. Robles, Mollie H. Wright, Kazutaka Takagi, Ze-Hong Miao, Keli K. Agama, Smitha Antony
Supplementary Figure 1 from Novel Indenoisoquinolines NSC 725776 and NSC 724998 Produce Persistent Topoisomerase I Cleavage Complexes and Overcome Multidrug Resistance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2055b6e4c927bba8f9bd53f8d257249
https://doi.org/10.1158/0008-5472.22370723
https://doi.org/10.1158/0008-5472.22370723
Autor:
Yves Pommier, Mark Cushman, Andrew Morrell, Muthukaman Nagarajan, Lyuba Varticovski, Ana I. Robles, Mollie H. Wright, Kazutaka Takagi, Ze-Hong Miao, Keli K. Agama, Smitha Antony
Supplementary Legends 1-2 from Novel Indenoisoquinolines NSC 725776 and NSC 724998 Produce Persistent Topoisomerase I Cleavage Complexes and Overcome Multidrug Resistance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2cb34828216563fb3e16c2c830f2fd0b
https://doi.org/10.1158/0008-5472.22370714.v1
https://doi.org/10.1158/0008-5472.22370714.v1
Autor:
Yves Pommier, Mark Cushman, Andrew Morrell, Muthukaman Nagarajan, Lyuba Varticovski, Ana I. Robles, Mollie H. Wright, Kazutaka Takagi, Ze-Hong Miao, Keli K. Agama, Smitha Antony
Supplementary Figure 2 from Novel Indenoisoquinolines NSC 725776 and NSC 724998 Produce Persistent Topoisomerase I Cleavage Complexes and Overcome Multidrug Resistance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d0e9487e8173d3ab78a45adcc63a1d4
https://doi.org/10.1158/0008-5472.22370717.v1
https://doi.org/10.1158/0008-5472.22370717.v1
Autor:
Yves Pommier, Mark Cushman, Andrew Morrell, Muthukaman Nagarajan, Lyuba Varticovski, Ana I. Robles, Mollie H. Wright, Kazutaka Takagi, Ze-Hong Miao, Keli K. Agama, Smitha Antony
Camptothecin (CPT) derivatives are effective anticancer drugs, especially against solid tumors. As CPTs are chemically unstable and have clinical limitations, we have synthesized indenoisoquinolines as novel topoisomerase I (Top1) inhibitors. We pres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::381ff7da4f951f0811fb86bb6f789f58
https://doi.org/10.1158/0008-5472.c.6496505.v1
https://doi.org/10.1158/0008-5472.c.6496505.v1
Autor:
Muthukaman, Nagarajan, Deshmukh, Sanjay, Tambe, Macchindra, Pisal, Dnyandeo, Tondlekar, Shital, Shaikh, Mahamadhanif, Sarode, Neelam, Kattige, Vidya G., Sawant, Pooja, Pisat, Monali, Karande, Vikas, Honnegowda, Srinivasa, Kulkarni, Abhay, Behera, Dayanidhi, Jadhav, Satyawan B., Sangana, Ramchandra R., Gudi, Girish S., Khairatkar-Joshi, Neelima, Gharat, Laxmikant A.
Publikováno v:
In Bioorganic & Medicinal Chemistry Letters 15 April 2018 28(7):1211-1218
Autor:
Muthukaman, Nagarajan, Tambe, Macchindra, Deshmukh, Sanjay, Pisal, Dnyandeo, Tondlekar, Shital, Shaikh, Mahamadhanif, Sarode, Neelam, Kattige, Vidya G., Pisat, Monali, Sawant, Pooja, Honnegowda, Srinivasa, Karande, Vikas, Kulkarni, Abhay, Behera, Dayanidhi, Jadhav, Satyawan B., Sangana, Ramchandra R., Gudi, Girish S., Khairatkar-Joshi, Neelima, Gharat, Laxmikant A.
Publikováno v:
In Bioorganic & Medicinal Chemistry Letters 1 December 2017 27(23):5131-5138
Akademický článek
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Autor:
Muthukaman, Nagarajan, Tambe, Macchindra, Shaikh, Mahamadhanif, Pisal, Dnyandeo, Deshmukh, Sanjay, Tondlekar, Shital, Sarode, Neelam, Narayana, Lakshminarayana, Gajera, Jitendra M., Kattige, Vidya G., Honnegowda, Srinivasa, Karande, Vikas, Kulkarni, Abhay, Behera, Dayanidhi, Jadhav, Satyawan B., Gudi, Girish S., Khairatkar-Joshi, Neelima, Gharat, Laxmikant A.
Publikováno v:
In Bioorganic & Medicinal Chemistry Letters 1 June 2017 27(11):2594-2601
Autor:
Muthukaman, Nagarajan, Deshmukh, Sanjay, Sarode, Neelam, Tondlekar, Shital, Tambe, Macchindra, Pisal, Dnyandeo, Shaikh, Mahamadhanif, Kattige, Vidya G., Honnegowda, Srinivasa, Karande, Vikas, Kulkarni, Abhay, Jadhav, Satyawan B., Mahat, Mahamad Yunnus A., Gudi, Girish S., Khairatkar-Joshi, Neelima, Gharat, Laxmikant A.
Publikováno v:
In Bioorganic & Medicinal Chemistry Letters 15 December 2016 26(24):5977-5984
Autor:
Smitha Antony, Andrew Morrell, Muthusamy Jayaraman, Alexandra Ioanoviciu, Mark Cushman, Marintha Rae Meckley, Melinda G. Hollingshead, Yves Pommier, Muthukaman Nagarajan, Brian M. Fox
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 16:4395-4399
The indenoisoquinolines are a novel class of non-camptothecin topoisomerase I (Top1) inhibitors whose mechanism of action involves trapping the covalent complex formed between DNA and Top1 during cellular processes. As an ongoing evaluation of the in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6830f64f6c67311d64ef3ff8960abbcf
https://doi.org/10.1016/j.bmcl.2006.05.048
https://doi.org/10.1016/j.bmcl.2006.05.048