Zobrazeno 1 - 10
of 61
pro vyhledávání: '"Muthugapatti K. Kandasamy"'
Autor:
Claudia Baumann, Xiangyu Zhang, Muthugapatti K. Kandasamy, Xiaohan Mei, Shiyou Chen, Kayvan F. Tehrani, Luke J. Mortensen, Wendy Watford, Ashley Lall, Rabindranath De La Fuente
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-16 (2023)
Abstract The mechanisms leading to changes in mesoscale chromatin organization during cellular aging are unknown. Here, we used transcriptional activator-like effectors, RNA-seq and superresolution analysis to determine the effects of genotoxic stres
Externí odkaz:
https://doaj.org/article/49ca4c86ce464ed3952593c62a21d619
Autor:
Claudia Baumann, Wei Ma, Xiaotian Wang, Muthugapatti K. Kandasamy, Maria M. Viveiros, Rabindranath De La Fuente
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
Centromeres are the sites of kinetochore and inner centromere formation, which can be epigenetically regulated. Here, the authors reveal a role for the lymphocyte specific helicase LSH/Hells associated with pericentric heterochromatin formation in ce
Externí odkaz:
https://doaj.org/article/c3cbd3e96cf44ad4bd3f3ff48818c972
Publikováno v:
Plant and Cell Physiology. 62:53-65
Secondary wall deposition in xylem vessels is activated by Vascular-Related NAC Domain proteins (VNDs) that belong to a group of secondary wall NAC (SWN) transcription factors. By contrast, Xylem NAC Domain1 (XND1) negatively regulates secondary wall
Autor:
Xiaotian Wang, Wei Ma, Rabindranath De La Fuente, Maria M. Viveiros, Muthugapatti K. Kandasamy, Claudia Baumann
Publikováno v:
Nature Communications
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
Centromeres are epigenetically determined nuclear domains strictly required for chromosome segregation and genome stability. However, the mechanisms regulating centromere and kinetochore chromatin modifications are not known. Here, we demonstrate tha
Publikováno v:
Cytoskeleton. 72:80-92
Actin interacts with a wide variety of cytoplasmic and nuclear proteins to support spatial development in nearly all eukaryotes. Null mutations in plant vegetative actins produce dramatically altered cell, tissue, and organ morphologies. Animal cytop
Autor:
Elizabeth C. McKinney, Richard B. Meagher, Suresh Ambati, Clifton A. Baile, Diane L. Hartzell, Ping Yu, Muthugapatti K. Kandasamy
Publikováno v:
BMC obesity
Background Obesity-related comorbidities are thought to result from the reprogramming of the epigenome in numerous tissues and cell types, and in particular, mature adipocytes within visceral and subcutaneous adipose tissue, VAT and SAT. The cell-typ
Publikováno v:
Cytoskeleton. 67:729-743
Conventional actin has been implicated in various nuclear processes including chromatin remodeling, transcription, nuclear transport, and overall nuclear structure. Moreover, actin has been identified as a component of several chromatin remodeling co
Publikováno v:
Plant Signaling & Behavior. 5:518-522
Nuclear Actin-Related Proteins (ARPs) and actin combine as heterodimers to bind a large helicase subunit and form a core complex essential to the assembly and function of most chromatin remodeling and modifying machines. They are the most common shar
Publikováno v:
The Plant Cell. 21:701-718
The relative significance of gene regulation and protein isovariant differences remains unexplored for most gene families, particularly those participating in multicellular development. Arabidopsis thaliana encodes three vegetative actins, ACT2, ACT7
Autor:
Bradley L. Rauh, Jen Sheen, Richard B. Meagher, Brandon d. Moore, Xiaoxia Xia, Muthugapatti K. Kandasamy, Abhijit Karve
Publikováno v:
Planta. 228:411-425
Arabidopsis hexokinase1 (HXK1) is a moonlighting protein that has separable functions in glucose signaling and in glucose metabolism. In this study, we have characterized expression features and glucose phosphorylation activities of the six HXK gene