Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Muthiah Bose"'
Publikováno v:
PLoS ONE, Vol 7, Iss 4, p e34475 (2012)
Photodynamic Therapy (PDT) involves the administration of a tumor localizing photosensitizing agent, which upon activation with light of an appropriate wavelength leads to the destruction of the tumor cells. The aim of the present study was to determ
Externí odkaz:
https://doaj.org/article/f03556acd7034c8d80383d086022aeb5
Autor:
Niina Laurila, Katri Pylkäs, Katrin Rapakko, Thomas W. P. Friedl, Hellevi Peltoketo, Heli Nevanlinna, Muthiah Bose, Robert Winqvist, Hanna Tuppurainen, Jonas Willmann, Lisa Wiesmüller, Kerstin Borgmann, Ann Christin Parplys, Helmut Pospiech, Felix Meyer, Juliane Sachsenweger, Lisa Heiserich, Johannes Jungwirth, Pentti Nieminen, Marco Groth
Publikováno v:
Human Molecular Genetics.
Whilst heterozygous germline mutations in the ABRAXAS1 gene have been associated with a hereditary predisposition to breast cancer, their effect on promoting tumourigenesis at the cellular level has not been explored. Here, we demonstrate in patient-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9adb580fd16e0337071f0ca0b2bc7df1
https://doi.org/10.1093/hmg/ddz252
https://doi.org/10.1093/hmg/ddz252
Autor:
Bing Xia, Kerstin Borgmann, Katri Pylkäs, Helmut Pospiech, Melissa C. Southey, Felix Meyer, Robert Winqvist, William D. Foulkes, Niina Laurila, Muthiah Bose
Publikováno v:
Cancer Research. 80:2335-2335
During the last decade, PALB2 has been defined as a high-risk breast cancer susceptibility gene alongside BRCA1 and BRCA2. Heterozygous mutation in PALB2 increases the lifetime breast cancer risk of female carriers to an average of 53%, but the risk
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::07f6aba02fceeb7a7973e1b3b7951920
https://doi.org/10.1158/1538-7445.am2020-2335
https://doi.org/10.1158/1538-7445.am2020-2335
Autor:
Lisa Wiesmüller, Hellevi Peltoketo, Thomas W. Dunlop, Jonas Willmann, Ganapathy Raman Devarajan, Lisa Heiserich, Hanna Tuppurainen, Robert Winqvist, Katri Pylkas, Pentti Nieminen, Kerstin Borgmann, Niina Laurila, Marco Groth, Felix Meyer, Muthiah Bose, Leila Eshraghi, Katrin Rapakko, Thomas Wolfram Paul Friedl, Juliane Sachsenweger, Helmut Pospiech, Ann Christin Parplys, Heli Nevanlinna
Publikováno v:
Cancer Research. 78:339-339
Whilst heterozygous germline mutations in the ABRAXAS gene have been associated with hereditary breast cancer predisposition, their initial effect on promoting tumorigenesis at the cellular level has not been explored. Here, we demonstrate in patient
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::77c04509a8d8485be81cc5b0b858ac98
https://doi.org/10.1158/1538-7445.am2018-339
https://doi.org/10.1158/1538-7445.am2018-339
Autor:
Reihaneh Zarrizi, Martin R. Higgs, Karolin Voßgröne, Maria Rossing, Birgitte Bertelsen, Muthiah Bose, Arne Nedergaard Kousholt, Heike Rösner, the COMPLEXO Network, Bent Ejlertsen, Grant S. Stewart, Finn Cilius Nielsen, Claus S. Sørensen
Publikováno v:
J Clin Invest
Zarrizi, R, Higgs, M R, Voßgröne, K, Rossing, M, Bertelsen, B, Bose, M, Kousholt, A N, Rösner, H, Network, T C, Ejlertsen, B, Stewart, G S, Nielsen, F C & Sørensen, C S 2020, ' Germline RBBP8 variants associated with early-onset breast cancer compromise replication fork stability ', The Journal of Clinical Investigation, vol. 130, no. 8, pp. 4069-4080 . https://doi.org/10.1172/JCI127521
Journal of Clinical Investigation
Zarrizi, R, Higgs, M R, Voßgröne, K, Rossing, M, Bertelsen, B, Bose, M, Kousholt, A N, Rösner, H, Network, T C, Ejlertsen, B, Stewart, G S, Nielsen, F C & Sørensen, C S 2020, ' Germline RBBP8 variants associated with early-onset breast cancer compromise replication fork stability ', The Journal of Clinical Investigation, vol. 130, no. 8, pp. 4069-4080 . https://doi.org/10.1172/JCI127521
Journal of Clinical Investigation
Haploinsufficiency of factors governing genome stability underlies hereditary breast and ovarian cancer. One significant pathway that is disabled as a result is homologous recombination repair (HRR). With the aim of identifying new candidate genes, w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42c708df10c7b23186c30d5d646b10a9
Autor:
Jan Benada, Finn Cilius Nielsen, Savvas Kinalis, Muthiah Bose, Maria Rossing, Jayashree Vijay Thatte, Claus Storgaard Sørensen, Bent Ejlertsen
Publikováno v:
Breast Cancer Research and Treatment
Bose, M, Benada, J, Thatte, J V, Kinalis, S, Ejlertsen, B, Nielsen, F C, Sørensen, C S & Rossing, M 2022, ' A catalog of curated breast cancer genes ', Breast Cancer Research and Treatment, vol. 191, pp. 431-441 . https://doi.org/10.1007/s10549-021-06441-y
Bose, M, Benada, J, Thatte, J V, Kinalis, S, Ejlertsen, B, Nielsen, F C, Sørensen, C S & Rossing, M 2022, ' A catalog of curated breast cancer genes ', Breast Cancer Research and Treatment, vol. 191, pp. 431-441 . https://doi.org/10.1007/s10549-021-06441-y
Purpose Decades of research have identified multiple genetic variants associated with breast cancer etiology. However, there is no database that archives breast cancer genes and variants responsible for predisposition. We set out to build a dynamic r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8b9fa433dcaa395b6788a010323d5f1