International Harmonization of Nomenclature and Diagnostic Criteria (INHAND): Nonproliferative and Proliferative Lesions of the Dog

Autor: Jochen Woicke, Muthafar M. Al-Haddawi, Jean-Guy Bienvenu, Jessica M. Caverly Rae, Franck J. Chanut, Karyn Colman, John M. Cullen, Wendell Davis, Ryo Fukuda, Maike Huisinga, Ursula Junker Walker, Kiyonori Kai, Ramesh C. Kovi, Nicholas P. Macri, Heike-Antje Marxfeld, Kristen J. Nikula, Ingrid D. Pardo, Thomas J. Rosol, Alok K. Sharma, Bhanu P. Singh, Kazutoshi Tamura, Michael S. Thibodeau, Enrico Vezzali, Justin D. Vidal, Emily K. Meseck

Publikováno v: Toxicologic Pathology. 49:5-109

The INHAND (International Harmonization of Nomenclature and Diagnostic Criteria for Lesions) Project ( www.toxpath.org/inhand.asp ) is a joint initiative of the societies of toxicologic Pathology from Europe (ESTP), Great Britain (BSTP), Japan (JSTP)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff6c7853ca62350eb8e995507fa8b2e2
https://doi.org/10.1177/0192623320968181

Toxicologic Pathology Forum: Opinion on Not Euthanizing Control Animals in the Recovery Phase of Non-Rodent Toxicology Studies.

Autor: Janardhan KS; AbbVie, Inc., North Chicago, Illinois, USA.; Merck & Co., Inc., Rahway, New Jersey, USA., Sura R; Gilead Sciences, Inc., Foster City, California, USA., Salian-Mehta S; Gilead Sciences, Inc., Foster City, California, USA., Flandre T; Novartis, Basel, Switzerland., Palazzi X; Pfizer, Groton, Connecticut, USA., Zane D; Gilead Sciences, Inc., Foster City, California, USA., Singh B; Gilead Sciences, Inc., Foster City, California, USA., Jacob B; Merck & Co., Inc., Rahway, New Jersey, USA., Hukkanen RR; Eisai, Inc., Cambridge, Massachusetts, USA., Al-Haddawi M; Bristol Myers Squibb, New Brunswick, New Jersey, USA., Bennet B; Magenta Therapeutics, Cambridge, Massachusetts, USA., Laast V; Labcorp Early Development Laboratories Inc., Madison, Wisconsin, USA., Lee D; Genentech, San Francisco, California, USA., Peterson R 2nd; AbbVie, Inc., North Chicago, Illinois, USA., Romeike A; Labcorp Early Development Services GmbH, Muenster, Germany., Schorsch F; Bayer SAS, Sophia-Antipolis, France., Guffroy M; AbbVie, Inc., North Chicago, Illinois, USA.

Publikováno v: Toxicologic pathology [Toxicol Pathol] 2022 Dec; Vol. 50 (8), pp. 950-956. Date of Electronic Publication: 2022 Oct 13.

PRDM15 is a key regulator of metabolism critical to sustain B-cell lymphomagenesis.

Autor: Mzoughi S; Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.; Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.; Department of Oncological Sciences, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Fong JY; Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.; NUS Graduate School for Integrative Sciences and Engineering, National University of Singapore, Singapore, Singapore., Papadopoli D; Lady Davis Institute, SMBD JGH, McGill University, Gerald Bronfman Department of Oncology, McGill University, Montreal, QC, H3T 1E2, Canada., Koh CM; Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore., Hulea L; Lady Davis Institute, SMBD JGH, McGill University, Gerald Bronfman Department of Oncology, McGill University, Montreal, QC, H3T 1E2, Canada.; Maisonneuve-Rosemont Hospital Research Centre, 5415 Assumption Blvd, Montreal, QC, H1T 2M4, Canada.; Département de Médecine, Université de Montréal, CP 6128, Succursale Centre-Ville, Montréal, QC, H3C 3J7, Canada., Pigini P; Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.; Department of Pharmacy and Biotechnology, University of Bologna, Via F. Selmi 3, 40126, Bologna, Italy., Di Tullio F; Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore., Andreacchio G; Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.; Department of Pharmacy and Biotechnology, University of Bologna, Via F. Selmi 3, 40126, Bologna, Italy., Hoppe MM; Cancer Science Institute (CSI), National University of Singapore, Singapore, Singapore., Wollmann H; Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore., Low D; Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore., Caldez MJ; Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.; Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.; Immunology Frontiers Research Center, Osaka University, 3-1 Yamada-oka, Suita, 565-0871, Japan., Peng Y; Cancer Science Institute (CSI), National University of Singapore, Singapore, Singapore., Torre D; Department of Oncological Sciences, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Zhao JN; Department of Oncological Sciences, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Uchenunu O; Lady Davis Institute, SMBD JGH, McGill University, Gerald Bronfman Department of Oncology, McGill University, Montreal, QC, H3T 1E2, Canada., Varano G; Department of Oncological Sciences, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Immunology Institute and Graduate School of Biomedical Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Motofeanu CM; Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore., Lakshmanan M; Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore., Teo SX; Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore., Wun CM; Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore., Perini G; Department of Pharmacy and Biotechnology, University of Bologna, Via F. Selmi 3, 40126, Bologna, Italy., Tan SY; Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.; Advanced Molecular Pathology Laboratory, IMCB, Singapore, Singapore.; Department of Pathology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore., Ong CB; Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.; Advanced Molecular Pathology Laboratory, IMCB, Singapore, Singapore., Al-Haddawi M; Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.; Advanced Molecular Pathology Laboratory, IMCB, Singapore, Singapore., Rajarethinam R; Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.; Advanced Molecular Pathology Laboratory, IMCB, Singapore, Singapore., Hue SS; Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.; Department of Pathology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.; National University Hospital (NUH), Singapore, Singapore., Lim ST; Division of Medical Oncology, National Cancer Centre Singapore, Singapore, Singapore.; Duke-NUS Graduate Medical School, Singapore, Singapore., Ong CK; Duke-NUS Graduate Medical School, Singapore, Singapore.; Division of Cellular and Molecular Research, National Cancer Centre Singapore, Singapore, Singapore.; Genome Institute of Singapore (GIS), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore., Huang D; Division of Cellular and Molecular Research, National Cancer Centre Singapore, Singapore, Singapore., Ng SB; Cancer Science Institute (CSI), National University of Singapore, Singapore, Singapore.; Department of Pathology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore., Bernstein E; Department of Oncological Sciences, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Hasson D; Department of Oncological Sciences, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Wee KB; Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore., Kaldis P; Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore., Jeyasekharan A; Cancer Science Institute (CSI), National University of Singapore, Singapore, Singapore., Dominguez-Sola D; Department of Oncological Sciences, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Immunology Institute and Graduate School of Biomedical Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Topisirovic I; Lady Davis Institute, SMBD JGH, McGill University, Gerald Bronfman Department of Oncology, McGill University, Montreal, QC, H3T 1E2, Canada. ivan.topisirovic@mcgill.ca.; Lady Davis Institute, SMBD JGH, McGill University, Departments of Experimental Medicine and Biochemistry, McGill University, Montreal, QC, H3T 1E2, Canada. ivan.topisirovic@mcgill.ca., Guccione E; Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore. ernesto.guccione@mssm.edu.; Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore. ernesto.guccione@mssm.edu.; Department of Oncological Sciences, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA. ernesto.guccione@mssm.edu.; Mount Sinai Center for Therapeutics Discovery, Department of Oncological and Pharmacological Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA. ernesto.guccione@mssm.edu.

Publikováno v: Nature communications [Nat Commun] 2020 Jul 14; Vol. 11 (1), pp. 3520. Date of Electronic Publication: 2020 Jul 14.

PRDM15 safeguards naive pluripotency by transcriptionally regulating WNT and MAPK-ERK signaling.

Autor: Mzoughi S; Methyltransferases in Development and Disease Group, Institute of Molecular and Cell Biology, Agency for Science, Technology and Research (A*STAR), Singapore.; Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore., Zhang J; Methyltransferases in Development and Disease Group, Institute of Molecular and Cell Biology, Agency for Science, Technology and Research (A*STAR), Singapore., Hequet D; Methyltransferases in Development and Disease Group, Institute of Molecular and Cell Biology, Agency for Science, Technology and Research (A*STAR), Singapore., Teo SX; Methyltransferases in Development and Disease Group, Institute of Molecular and Cell Biology, Agency for Science, Technology and Research (A*STAR), Singapore., Fang H; Epigenetics and Cell Fates Group, Institute of Molecular and Cell Biology, Agency for Science, Technology and Research (A*STAR), Singapore., Xing QR; Epigenetics and Cell Fates Group, Institute of Molecular and Cell Biology, Agency for Science, Technology and Research (A*STAR), Singapore.; School of Biological Sciences, Nanyang Technological University, Singapore., Bezzi M; Methyltransferases in Development and Disease Group, Institute of Molecular and Cell Biology, Agency for Science, Technology and Research (A*STAR), Singapore.; Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore., Seah MKY; Developmental Epigenetics and Disease Group, Institute of Molecular and Cell Biology, Agency for Science, Technology and Research (A*STAR), Singapore., Ong SLM; Institute of Medical Biology (IMB), Agency for Science, Technology and Research (A*STAR), Singapore., Shin EM; Cancer Science Institute of Singapore (CSI), National University of Singapore, Singapore.; NF-κB Signaling in Human Ailments, Institute of Molecular and Cell Biology, Agency for Science, Technology and Research (A*STAR), Singapore., Wollmann H; DNA Sequencing Facility NGS Unit, Institute of Molecular and Cell Biology, Agency for Science, Technology and Research (A*STAR), Singapore., Wong ESM; Institute of Medical Biology (IMB), Agency for Science, Technology and Research (A*STAR), Singapore., Al-Haddawi M; Advanced Molecular Pathology Laboratory, IMCB, Singapore., Stewart CL; Institute of Medical Biology (IMB), Agency for Science, Technology and Research (A*STAR), Singapore., Tergaonkar V; Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.; NF-κB Signaling in Human Ailments, Institute of Molecular and Cell Biology, Agency for Science, Technology and Research (A*STAR), Singapore.; National Cancer Centre Singapore, Singapore.; Centre for Cancer Biology, University of South Australia and SA Pathology, Adelaide, South Australia, Australia., Loh YH; Epigenetics and Cell Fates Group, Institute of Molecular and Cell Biology, Agency for Science, Technology and Research (A*STAR), Singapore.; Department of Biological Sciences, National University of Singapore, Singapore., Dunn NR; Institute of Medical Biology (IMB), Agency for Science, Technology and Research (A*STAR), Singapore., Messerschmidt DM; Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.; Developmental Epigenetics and Disease Group, Institute of Molecular and Cell Biology, Agency for Science, Technology and Research (A*STAR), Singapore., Guccione E; Methyltransferases in Development and Disease Group, Institute of Molecular and Cell Biology, Agency for Science, Technology and Research (A*STAR), Singapore.; Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.; Cancer Science Institute of Singapore (CSI), National University of Singapore, Singapore.; National Cancer Centre Singapore, Singapore.; Department of Oncological Sciences, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, New York, USA.

Publikováno v: Nature genetics [Nat Genet] 2017 Sep; Vol. 49 (9), pp. 1354-1363. Date of Electronic Publication: 2017 Jul 24.

Natural myocardial ECM patch drives cardiac progenitor based restoration even after scarring.

Autor: Sarig U; School of Materials and Science Engineering, Nanyang Technological University, Singapore 639798, Singapore., Sarig H; School of Materials and Science Engineering, Nanyang Technological University, Singapore 639798, Singapore., de-Berardinis E; School of Materials and Science Engineering, Nanyang Technological University, Singapore 639798, Singapore., Chaw SY; School of Materials and Science Engineering, Nanyang Technological University, Singapore 639798, Singapore., Nguyen EBV; School of Materials and Science Engineering, Nanyang Technological University, Singapore 639798, Singapore., Ramanujam VS; Yong Loo Lin School of Medicine, National University of Singapore, Singapore 119228, Singapore., Thang VD; Yong Loo Lin School of Medicine, National University of Singapore, Singapore 119228, Singapore., Al-Haddawi M; Institute of Molecular and Cell Biology, Agency for Science, Technology and Research, Singapore 138673, Singapore., Liao S; School of Materials and Science Engineering, Nanyang Technological University, Singapore 639798, Singapore., Seliktar D; Yong Loo Lin School of Medicine, National University of Singapore, Singapore 119228, Singapore; Faculty of Biomedical Engineering, Technion - Israel Institute of Technology, Haifa 32000, Israel., Kofidis T; Yong Loo Lin School of Medicine, National University of Singapore, Singapore 119228, Singapore., Boey FYC; School of Materials and Science Engineering, Nanyang Technological University, Singapore 639798, Singapore., Venkatraman SS; School of Materials and Science Engineering, Nanyang Technological University, Singapore 639798, Singapore. Electronic address: assubbu@ntu.edu.sg., Machluf M; School of Materials and Science Engineering, Nanyang Technological University, Singapore 639798, Singapore; Faculty of Biotechnology and Food Engineering, Technion - Israel Institute of Technology, Haifa 32000, Israel. Electronic address: machlufm@tx.technion.ac.il.

Publikováno v: Acta biomaterialia [Acta Biomater] 2016 Oct 15; Vol. 44, pp. 209-220. Date of Electronic Publication: 2016 Aug 18.