Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Mutant KRAS cancers"'
Akademický článek
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Autor:
Kyle Begovich, Angela Schoolmeesters, Navin Rajapakse, Maneesh Kumar, Elena Martinez-Terroba, Arvind Shakya, Brandon Whitefield, Nataraj Pagadala, Aparajita Chourasia, Leah Fung
Publikováno v:
Molecular Cancer Research. 21:B002-B002
Although oncogenic Kirsten rat sarcoma virus (KRAS) was once deemed undruggable, recent advances have revealed promising anti-tumor effects with pan-KRAS and KRAS-mutant specific inhibitors in both preclinical and clinical settings. Despite the succe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3a77eb2c49bf30a8b316090e83b8e3ee
https://doi.org/10.1158/1557-3125.ras23-b002
https://doi.org/10.1158/1557-3125.ras23-b002
Publikováno v:
Cancer Gene Therapy Week; 11/16/2023, p49-49, 1p
The discovery of functionally relevant KRAS effectors in lung and PDAC may yield novel molecular targets or mechanisms amenable to inhibition strategies. Here, we studied the role of PITPNC1 and its controlled network in the development and progressi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______1111::3936bfa696ae91fd0a8d1736162506c6
https://hdl.handle.net/10171/65498
https://hdl.handle.net/10171/65498
Autor:
Tolani, Bhairavi, Celli, Anna, Yao, Yanmin, Tan, Yong Zi, Fetter, Richard, Liem, Christina R., de Smith, Adam J., Vasanthakumar, Thamiya, Bisignano, Paola, Cotton, Adam D., Seiple, Ian B., Rubinstein, John L., Jost, Marco, Weissman, Jonathan S.
Publikováno v:
Nature Biotechnology; Dec2022, Vol. 40 Issue 12, p1834-1844, 11p
Publikováno v:
BioEssays; Aug2022, Vol. 44 Issue 8, p1-8, 8p
Autor:
Fong, Zhijack, Lee, Wai-Leng
Publikováno v:
Future Medicinal Chemistry; Jun2022, Vol. 14 Issue 11, p827-845, 19p
Publikováno v:
Cancer Gene Therapy Week; 7/1/2024, p70-70, 1p
Autor:
Ghaddar, Nour, Wang, Shuo, Woodvine, Bethany, Krishnamoorthy, Jothilatha, van Hoef, Vincent, Darini, Cedric, Kazimierczak, Urszula, Ah-son, Nicolas, Popper, Helmuth, Johnson, Myriam, Officer, Leah, Teodósio, Ana, Broggini, Massimo, Mann, Koren K., Hatzoglou, Maria, Topisirovic, Ivan, Larsson, Ola, Le Quesne, John, Koromilas, Antonis E.
Publikováno v:
Nature Communications; 7/30/2021, Vol. 12 Issue 1, p1-15, 15p
Autor:
Zhong, Siying, Wayne, Joanne
Publikováno v:
Future Medicinal Chemistry; Feb2022, Vol. 14 Issue 3, p127-129, 3p