New antiplasmodial 4-amino-thieno[3,2-d]pyrimidines with improved intestinal permeability and microsomal stability

Autor: Lagardère, Prisca, Mustière, Romain, Amanzougaghene, Nadia, Hutter, Sébastien, Casanova, Marion, Franetich, Jean-François, Tajeri, Shahin, Malzert-Fréon, Aurélie, Corvaisier, Sophie, Azas, Nadine, Vanelle, Patrice, Verhaeghe, Pierre, Primas, Nicolas, Mazier, Dominique, Masurier, Nicolas, Lisowski, Vincent

Publikováno v: In European Journal of Medicinal Chemistry 5 March 2023 249

Synthesis of antiplasmodial 2-aminothieno[3,2-d]pyrimidin-4(3H)-one analogues using the scaffold hopping strategy

Autor: Mustière, Romain, Lagardère, Prisca, Hutter, Sébastien, Dell’Orco, Viviana, Amanzougaghene, Nadia, Tajeri, Shahin, Franetich, Jean-François, Corvaisier, Sophie, Since, Marc, Malzert-Fréon, Aurélie, Masurier, Nicolas, Lisowski, Vincent, Verhaeghe, Pierre, Mazier, Dominique, Azas, Nadine, Vanelle, Patrice, Primas, Nicolas

Publikováno v: In European Journal of Medicinal Chemistry 5 November 2022 241

4-Substituted Thieno[3,2- d ]pyrimidines as Dual-Stage Antiplasmodial Derivatives.

Autor: Lagardère, Prisca¹ (AUTHOR) prisca.lagardere@umontpellier.fr, Mustière, Romain² (AUTHOR) romain.mustiere@etu.univ-amu.fr, Amanzougaghene, Nadia³ (AUTHOR) amanzougaghene_nadia@yahoo.fr, Hutter, Sébastien⁴ (AUTHOR) sebastien.hutter@univ-amu.fr, Franetich, Jean-François³ (AUTHOR) jean-francois.franetich@upmc.fr, Azas, Nadine⁴ (AUTHOR) nadine.azas@univ-amu.fr, Vanelle, Patrice^2,5 (AUTHOR) patrice.vanelle@univ-amu.fr, Verhaeghe, Pierre^6,7 (AUTHOR) pierre.verhaeghe@lcc-toulouse.fr, Primas, Nicolas^2,5 (AUTHOR) nicolas.primas@univ-amu.fr, Mazier, Dominique³ (AUTHOR) dominique.mazier@sorbonne-universite.fr, Masurier, Nicolas¹ (AUTHOR) nicolas.masurier@umontpellier.fr, Lisowski, Vincent¹ (AUTHOR) nicolas.masurier@umontpellier.fr

Publikováno v: Pharmaceuticals (14248247). Jul2022, Vol. 15 Issue 7, pN.PAG-N.PAG. 18p.

Enteric pathogenic bacteria and resistance gene carriage in the homeless population in Marseille, France

Autor: Ly, Tran Duc Anh, Hadjadj, Linda, Hoang, van Thuan, Goumbala, Ndiaw, Dao, Thi Loi, Badiaga, Sekene, Tissot-Dupont, Herve, Brouqui, Philippe, Raoult, Didier, Rolain, Jean-Marc, Gautret, Philippe, Bosson-Vanga, Henriette, Primas, Nicolas, Franetich, Jean-François, Lavazec, Catherine, Gomez, Lina, Ashraf, Kutub, Tefit, Maurel, Soulard, Valérie, Dereuddre-Bosquet, Nathalie, Le Grand, Roger, Donnette, Mélanie, Mustière, Romain, Amanzougaghene, Nadia, Tajeri, Shahin, Suzanne, Peggy, Malzert-Fréon, Aurélie, Rault, Sylvain, Vanelle, Patrice, Hutter, Sébastien, Cohen, Anita, Snounou, Georges, Roques, Pierre, Azas, Nadine, Lagardère, Prisca, Lisowski, Vincent, Masurier, Nicolas, Nguyen, Michel, Paloque, Lucie, Benoit-Vical, Françoise, Verhaeghe, Pierre, Mazier, Dominique

Publikováno v: Acta Microbiologica et Immunologica Hungarica
Acta Microbiologica et Immunologica Hungarica, Akadémiai Kiadó, 2021, 68 (1), pp.7-13. ⟨10.1556/030.2021.01346⟩
Acta Microbiologica et Immunologica Hungarica, 2021, 68 (1), pp.7-13. ⟨10.1556/030.2021.01346⟩

We aimed to assess the prevalence of pathogenic bacteria and resistance genes in rectal samples collected among homeless persons in Marseille, France. In February 2014 we enrolled 114 sheltered homeless adults who completed questionnaires and had rec

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b289ec668da9a311e50b28f6a1508cda
https://doi.org/10.1556/030.2021.01346

2-Cyclopropyl-6-phenyl-2,3-dihydrothieno[3,2-d][1,3,2]diazaborinin-4(1H)-one

Autor: Mustière, Romain, Vanelle, Patrice, Primas, Nicolas

Publikováno v: Molbank
Molbank, 2021, 2021 (2), ⟨10.3390/m1221⟩
Molbank, MDPI, 2021, 2021 (2), ⟨10.3390/m1221⟩
Molbank, Vol 2021, Iss M1221, p M1221 (2021)

As part of our ongoing scaffold hopping work on antimalarial 2-aminothieno[3,2-d]pyrimidin-4-one scaffold, we explored the dihydrothieno[3,2-d][1,3,2]diazaborinin-4(1H)-one as a potential new antimalarial series. Using conditions found in the literat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::9285f7cbe275f73dba0a22173f3d4ef1
https://hal-amu.archives-ouvertes.fr/hal-03246463