Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Mustapha Iddir"'
Autor:
Somia Debbabi, Marie-Christine Groleau, Myriam Létourneau, Chitra Narayanan, Laura-Lee Gosselin, Mustapha Iddir, Jacinthe Gagnon, Nicolas Doucet, Eric Déziel, David Chatenet
Publikováno v:
PLoS ONE, Vol 13, Iss 11, p e0207366 (2018)
The Pituitary Adenylate Cyclase-Activating Polypeptide (PACAP), a polycationic, amphiphilic and helical neuropeptide, is well known for its neuroprotective actions and cell penetrating properties. In the present study, we evaluated the potent antibac
Externí odkaz:
https://doaj.org/article/70cf9c0970c44726b7706881e1020beb
Autor:
Jean E. Lachowicz, Jean-Paul Castaigne, Borhane Annabi, Mustapha Iddir, Jean-Christophe Currie, Simon Lord-Dufour, Sasmita Tripathy, Michel Demeule, Anthony Regina
A. Confirmation of HER2-positive expression status of BT-474 and SKBR3 cells and HER2-negative status of MCF-7, U-87 and HBMEC cells by WB analysis using an anti-HER2 mAb. B. Immunodetection of LRP1 by WB using an antibody directed against the 85 kDa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2aaab8dbb02b6e6fc7dc6acfdbf2b914
https://doi.org/10.1158/1535-7163.22502209.v1
https://doi.org/10.1158/1535-7163.22502209.v1
Autor:
Jean E. Lachowicz, Jean-Paul Castaigne, Borhane Annabi, Mustapha Iddir, Jean-Christophe Currie, Simon Lord-Dufour, Sasmita Tripathy, Michel Demeule, Anthony Regina
A. In vitro binding of ANG4043 and Anti-HER2 mAb to the HER2/Fc chimera protein. B, C. Lack of effect of ANG4043 and Anti-HER2 on the proliferation of HER2-negative MCF-7 (B) and U-87 (C) cells using the [3H] thymidine incorporation assay.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7197983afa761dcae6f1e699123d51e
https://doi.org/10.1158/1535-7163.22502203.v1
https://doi.org/10.1158/1535-7163.22502203.v1
Autor:
Jean E. Lachowicz, Jean-Paul Castaigne, Borhane Annabi, Mustapha Iddir, Jean-Christophe Currie, Simon Lord-Dufour, Sasmita Tripathy, Michel Demeule, Anthony Regina
Legends to supplemental figures 1-4.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::676c61c35c3826af61b6be52509ac9da
https://doi.org/10.1158/1535-7163.22502197.v1
https://doi.org/10.1158/1535-7163.22502197.v1
Autor:
Majid D. Farahani, Tanos C. C. França, Saba Alapour, Fatma Shahout, Richard Boulon, Mustapha Iddir, Michael Maddalena, Yann Ayotte, Steven R. LaPlante
Publikováno v:
ChemMedChem. 17(10)
A focused drug repurposing approach is described where an FDA-approved drug is rationally selected for biological testing based on structural similarities to a fragment compound found to bind a target protein by an NMR screen. The approach is demonst
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6daa11c9ded3c2943a7e07f0f5c40c1e
https://pubmed.ncbi.nlm.nih.gov/35298873
https://pubmed.ncbi.nlm.nih.gov/35298873
Publikováno v:
Trends in pharmacological sciences. 40(10)
The urotensinergic system, comprised of a G protein-coupled receptor (UT) and two endogenous ligands named urotensin II (UII) and urotensin II-related peptide (URP), has garnered significant attention due to its involvement in the initiation and/or t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aab1caf48b4b1643d2351825a87e2ffd
https://pubmed.ncbi.nlm.nih.gov/31500846
https://pubmed.ncbi.nlm.nih.gov/31500846
Autor:
Jacinthe Gagnon, David Chatenet, Mustapha Iddir, Laura-Lee Gosselin, Somia Debbabi, Eric Déziel, Myriam Létourneau, Nicolas Doucet, Chitra Narayanan, Marie-Christine Groleau
Publikováno v:
PLoS ONE, Vol 13, Iss 11, p e0207366 (2018)
PLoS ONE
PLoS ONE
The Pituitary Adenylate Cyclase-Activating Polypeptide (PACAP), a polycationic, amphiphilic and helical neuropeptide, is well known for its neuroprotective actions and cell penetrating properties. In the present study, we evaluated the potent antibac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a001114932e675bab07e2784903ea86
http://europepmc.org/articles/PMC6248945?pdf=render
http://europepmc.org/articles/PMC6248945?pdf=render
Publikováno v:
Molecular Carcinogenesis. 55:148-160
Progression of astrocytic tumors is, in part, related to their dysregulated autophagy capacity. Recent evidence indicates that upstream autophagy signaling events can be triggered by MT1-MMP, a membrane-bound matrix metalloproteinase that contributes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ed28199aab84bb1ffa1fcf2d12bb8fd2
https://doi.org/10.1002/mc.22264
https://doi.org/10.1002/mc.22264
Autor:
Borhane Annabi, Jean-Paul Castaigne, Mustapha Iddir, Anthony Regina, Sasmita Tripathy, Jean E. Lachowicz, Jean-Christophe Currie, Simon Lord-Dufour, Michel Demeule
Publikováno v:
Molecular Cancer Therapeutics. 14:129-140
Anti-HER2 monoclonal antibodies (mAb) have been shown to reduce tumor size and increase survival in patients with breast cancer, but they are ineffective against brain metastases due to poor brain penetration. In previous studies, we identified a pep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3443f471f2cfe8e024f223a82e019919
https://doi.org/10.1158/1535-7163.mct-14-0399
https://doi.org/10.1158/1535-7163.mct-14-0399
Autor:
Hassan Nassour, David Chatenet, Laura Lee‐Gosselin, Etienne Billard, Mathilde Poujol de Molliens, Mustapha Iddir
Publikováno v:
Peptide Science. 111:e24056
The urotensinergic system, formed by a G protein‐coupled receptor (GPCR) termed UT and two endogenous peptide ligands Urotensin II (UII, H‐Glu‐Thr‐Pro‐Asp‐[Cys‐Phe‐Trp‐Lys‐Tyr‐Cys]‐Val‐OH) and Urotensin II‐related peptide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::521073b9709ae598acfa62378e1d3f0d
https://doi.org/10.1002/pep2.24056
https://doi.org/10.1002/pep2.24056