Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Mustapha Aoubala"'
Autor:
Johanna Campbell, David P. Lane, Georgia J. Pass, Mustapha Aoubala, Maureen Higgins, Oliver D. Staples, Nicholas J. Westwood, Michael J. R. Stark, Jonathan James Hollick, Alastair M. Thompson, Joanne Mathers, Sonia Lain, Karen Murray, Lee Baker, Julie A. Woods, Virginia Appleyard, Stephen J. Holland, Anna R. McCarthy
Publikováno v:
Cancer Cell
We have carried out a cell-based screen aimed at discovering small molecules that activate p53 and have the potential to decrease tumor growth. Here, we describe one of our hit compounds, tenovin-1, along with a more water-soluble analog, tenovin-6.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d38fb32b595a5b0ab7e554bf719e765
https://doi.org/10.1016/j.ccr.2008.03.004
https://doi.org/10.1016/j.ccr.2008.03.004
Autor:
Mustapha Aoubala, Paulo De Sepulveda, Robert Rottapel, Nathalie Casteran, Sébastien Letard, Nathalie Beslu, Patrice Dubreuil, Eric Lecocq
Publikováno v:
Oncogene. 22:4710-4722
Mutations of KIT receptor tyrosine kinase are found in the majority of patients with mastocytosis and in most gastrointestinal stromal tumors. Oncogenic KIT mutations in GISTs are located in the KIT juxtamembrane domain (JMD), while codon 816 in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c96ff47ca4d35c06c787ad20abf7ea69
https://doi.org/10.1038/sj.onc.1206587
https://doi.org/10.1038/sj.onc.1206587
Autor:
Laura Menotti, Marc Lopez, Mustapha Aoubala, Francesca Cocchi, Patrice Dubreuil, Gabriella Campadelli-Fiume
Publikováno v:
Proceedings of the National Academy of Sciences. 95:15700-15705
The herpesvirus entry mediator C (HveC), previously known as poliovirus receptor-related protein 1 (PRR1), and the herpesvirus Ig-like receptor (HIgR) are the bona fide receptors employed by herpes simplex virus-1 and -2 (HSV-1 and -2) for entry into
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e13dace58713e42e5a8a98a4df99446
https://doi.org/10.1073/pnas.95.26.15700
https://doi.org/10.1073/pnas.95.26.15700
Autor:
Abdelkarim Abousalham, Isabelle Douchet, Cécile Daniel, Youssef Gargouri, Mustapha Aoubala, Michel Hirn, Alain De Caro, Laurence de La Fournière, Robert Verger
Publikováno v:
Journal of Biological Chemistry. 270:3932-3937
Several monoclonal antibodies (mAbs) were prepared against human pancreatic lipase (HPL). Two enzyme-linked immunosorbent assay (ELISA) procedures were set up for screening hybridomas producing specific antibodies. Four mAbs (81-23, 146-40, 315-25, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::06ca01f8115eec9b6ec8ce485794be4d
https://doi.org/10.1074/jbc.270.8.3932
https://doi.org/10.1074/jbc.270.8.3932
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism. 1213:319-324
Human (HGL) and rabbit (RGL) gastric lipases were cleaved by trypsin and the resulting peptides were characterized. Exposure of HGL to trypsin led to the production of three identified fragments (H1, H2 and H3) resulting from cleavage sites at Lys-4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1838da89e5e3049396ecf64b31a16d75
https://doi.org/10.1016/0005-2760(94)00058-1
https://doi.org/10.1016/0005-2760(94)00058-1
Autor:
Kenneth Fernandes, Lee Baker, Mustapha Aoubala, Colin A. Purdie, David P. Lane, Philip R. Quinlan, Alastair M. Thompson, Anne-Catherine Prats, Alexandra Diot, Lee B. Jordan, Marie P. Khoury, Jean-Christophe Bourdon
Publikováno v:
Breast Cancer Research
Breast Cancer Research, 2011, 13 (1), pp.R7. ⟨10.1186/bcr2811⟩
Breast Cancer Research : BCR
Breast Cancer Research, 2011, 13 (1), pp.R7. ⟨10.1186/bcr2811⟩
Breast Cancer Research : BCR
International audience; INTRODUCTION: Normal function of the p53 network is lost in most cancers, often through p53 mutation. The clinical impact of p53 mutations in breast cancer remains uncertain, especially where p53 isoforms may modify the effect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::249bb866ece58453e097359911bf0051
https://doi.org/10.1186/bcr2811
https://doi.org/10.1186/bcr2811
Autor:
Alain De Caro, Mustapha Aoubala, Robert Verger, Margarita G. Ivanova, Joelle Hirn, Cécile Daniel
Publikováno v:
Colloids and Surfaces B: Biointerfaces. 1:17-22
Five monoclonal antibodies (MAbs) directed against human gastric lipase (HGL) were used as probes to characterize and locate the functional sites (catalytic and lipid binding domains) on the surface of the enzyme. Taking advantage of the low surface
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::09fc09152d3c5bc97e760b5ec28d8912
https://doi.org/10.1016/0927-7765(93)80013-o
https://doi.org/10.1016/0927-7765(93)80013-o
Autor:
Anne-Catherine Prats, H. Bernard, David P. Lane, Kenneth Fernandes, Mustapha Aoubala, F. Murray-Zmijewski, Marie P. Khoury, Sébastien Perrier, Jean-Christophe Bourdon
Publikováno v:
Cell Death and Differentiation
Cell Death and Differentiation, 2011, 18 (2), pp.248-58. ⟨10.1038/cdd.2010.91⟩
Cell Death and Differentiation, 2011, 18 (2), pp.248-58. ⟨10.1038/cdd.2010.91⟩
International audience; We have previously reported that the human p53 gene encodes at least nine different p53 isoforms, including Δ133p53α, which can modulate p53 transcriptional activity and apoptosis. In this study, we aimed to investigate the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59e7f9192a585004e39dfe185270dcca
https://pubmed.ncbi.nlm.nih.gov/20689555
https://pubmed.ncbi.nlm.nih.gov/20689555
Autor:
Mustapha Aoubala, S Perrier, Jean-Christophe Bourdon, Anne-Catherine Prats, Marie P. Khoury, F. Murray-Zmijewski, David P. Lane, Kenneth Fernandes
Publikováno v:
Breast Cancer Research : BCR
We recently reported that the human p53 gene encodes at least nine different p53 isoforms, two of which (p53β and Δ133p53) can modulate p53 transcriptional activity and apoptosis. In the present study, we aimed to investigate the regulation of Δ13
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::faecdd5656c242b8794bcaab294b0a47
https://doi.org/10.1186/bcr2505
https://doi.org/10.1186/bcr2505
