Enhancement of Th1 type cytokine production and primary T cell activation by PBI-1393

Autor: Nathalie Julien, Boulos Zacharie, Christopher Penney, Mustapha Allam, Lyne Gagnon

Publikováno v: Clinical Immunology. 125:318-327

In previous reports, we have shown that PBI-1393 (formerly BCH-1393), N,N-Dimethylaminopurine pentoxycarbonyl D -arginine, stimulates cytotoxic T-lymphocyte (CTL)responses both in vitro and in vivo in normal immune status and immunosuppressed mice.Ad

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28d9db656dc145acbb97289469642ecf
https://doi.org/10.1016/j.clim.2007.07.017

Inhibition of GM-CSF/IL-3/IL-5 Signaling by Antisense Oligodeoxynucleotides Targeting the Common Beta Chain of Their Receptors

Autor: Mustapha Allam, Paolo M. Renzi

Publikováno v: Antisense and Nucleic Acid Drug Development. 11:289-300

Granulocyte-macrophage colony-stimulating factor (GM-CSF), interleukin-3 (IL-3), and IL-5 play a key role in allergic inflammation. They mediate their effect via receptors that consist of two distinct subunits, a cytokine-specific alpha subunit and a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e459f73ef5431ece8e07d322a31cca43
https://doi.org/10.1089/108729001753231678

Presence of Platelet-derived Growth Factor in Normal and Fibrotic Lung Is Specifically Associated with Interstitial Macrophages, While Both Interstitial Macrophages and Alveolar Epithelial Cells Express the c-sis Proto-oncogene

Autor: Mustapha Allam, Michael Pech, Yves Martinet, Nadine Martinet, François Plénat, Jean-Michel Vignaud

Publikováno v: American Journal of Respiratory Cell and Molecular Biology. 5:531-538

Normal lung structure is maintained by the presence of mesenchymal cells and their extracellular matrix products. The slow normal turnover of these cells is disrupted in fibrotic disorders, resulting in the in situ accumulation of mesenchymal cells a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5959c850b219c55f6b95e1a79eeae2fa
https://doi.org/10.1165/ajrcmb/5.6.531

Acute renal failure - clinical studies - 3

Autor: Marcia Cristina da Silva Magro, Zouhir Oualim, M. Batur Canoz, I. Bobek, Anna Hawrot-Kawecka, Stefanie M. Bode-Boeger, Miguel A. Ribeiro, Stanislaw Wos, P. Piccinni, Brenda R. Hemmelgarn, Jan Dulawa, Nicu Olariu, Jan Stange, Serena Antniolli, Benedetta Ferri, Christian Joukhadar, C. Chion, Robert Faulhaber-Walter, Reinaldo F. Neto, Igor M. Santos, Jan T. Kielstein, Maristela Bohlke, Heiko Hickstein, Vlado Pusevski, Rinaldo Bellomo, Mustapha Allam, Sverrir Hardarson, Sandra Figueiredo, Ana Cortesão Costa, Emannuel Rivers, Burak Canver, Paolo Manunta, Veronica Testa, Mariana Bobic, Sehmus Ozmen, Helen Murray, Ken McCune, Agotha Borcanea, C. MacEwen, Elisa Lazzarich, Maurício de Nassau Machado, Lilia Nigro Maia, Sascha David, Giorgio Bellomo, Kaline Oliveira, Claudio Campieri, Susana Martins, Sebastian Klammt, Stephanie Brillhart, Alan Slade, Wojciech Domaradzki, Michael Burg, K. Soto, Belma Özlem Tural Balsak, Xueqing Yu, Atilla Sezgin, Piero Stratta, Grzegorz Kawecki, Jens Martens-Lobenhoffer, Ying Kuan, Ramesh Naik, Stefan Liebe, Nur Baykara, Oana Constantinescu, Gustavo Tragnago, José António Lopes, Alberto Zangrillo, Hartmut Hecker, Ioan Sporea, P. Lentini, Juliane Gruenert, Eric Hoste, Ligia Petrica, Gang Chen, Philip Kam-Tao Li, Kirsten Colpaert, Ana Paula Otaviano, Roman Mrozek, Davide Rossi, Vala Palmadottir, Sergio Stefoni, Patrick T. Murray, Mihael Potocki, Mohamed Hassani, Li Wang, Nathan I. Shapiro, Maria do Socorro Albuquerque, Michael Bennett, Marco Quaglia, Barbara Singh, Luis Resende, Virginia Trandafirescu, Paulo Percio Magro, Abdellali Bahadi, C. Ronco, Gheorghe Bozdog, Betul Erismis, Neesh Pannu, Robert Birkhan, A. Brendolan, Sebastian Koball, Kenneth Kupfner, Davut Akin, D. Cruz, Elena Bignami, Ana Maria Sararu, Judd E. Hollander, Carsten Hafer, Silvia Velciov, Antonio N. Diogo, Thomas Dumortier, Maria de Fatima Vattimo, Anna Mizzi, Arben Asani, Kamil Toker, Andrea Airoldi, Adelina Mihaescu, Paolo Calzavacca, Zola Mzimba, Hermann Haller, Joao Nobrega, Elizabeth De Francesco Daher, Scott Klarenbach, Anne Goetze, A. Fabbri, Joerg Emmerich, Stephen Trzeciak, Alper Usluogullari, Deidre Campbell, Liljana Tozija, Elena Brioni, Corina Vernic, Itir Yegenaga, Polianna Lemos Moura Moreira Albuquerque, Steffen Mitzner, Laura Madeira, Christian Mueller, M. de Cal, Prasad Devarajan, Saulo R. Garcez, Nele Brusselaers, Tobias Breidthardt, Seok-won Lee, Roberta Fenoglio, F. Basso, H. Martins, A. Borges, Jay L. Koyner, Geraldo Bezerra da Silva Junior, Sabrina Strube, Cristina Gluhovschi, Xiuling Chen, Flaviu Bob, F. Nalesso, Ken Kupfer, Rafael V. Barreto, Duska Dragun, Paulo Caruso, Joseane S. Santos, Zvezdana Petronijevic, Giovanni Landoni, Thorvaldur Magnusson, Robert Schmouder, Anja Haase-Fielitz, S. Soni, Olaf Burkhardt, Frei Ulrich, Stan Monstrey, Philipp Kümpers, Lukasz Chrobak, Koco Cakalaroski, Demet Yavuz, S. Auriemma, Alexander Lukasz, Luciana M.M. Barbosa, F. Garzotto, Jessica Vasconcelos, Paul Bateson, Matthew T. James, Johan Decruyenaere, M. Emin Yilmaz, Zhentong Wang, Adalbert Schiller, Tiffany Osborne, Kleyton A. Bastos, Nunzia Casamassima, Aleksandar Sikole, Fabiana Hirata, Ulysses dos Santos Torres, Geoffrey Block, Francesco Grammatico, M. Zanella, Chiara Lanzani, Fang Wang, Galina Savinova, Gheorghe Gluhovschi, Lindsey Barker, Manisha Sahay, Michael Haase, Tulio Reichert, L. Cunha, Volker Kliem, António Gomes da Costa, B. Rodrigues, Tobias Reichlin, I. Bolgan, Ana Carolina Brochado Geist, Rosana G. Bruetto, A.L. Papolia, Xiuchuan Yang, Franklin Correa Barcellos, Emmanuel A. Burdmann, Alessandro Ciavatti, Minghui Zhao, Kerstin Schuster, Brian Noland, Florica Gadalean, Mario G. Lopes, Ahmed Amer, Stijn Blot, Catrin Oye, A. D'Onofrio, Margrét Birna Andrésdóttir, Markus Noveanu, Pedro T. L. Pereira, F. Nurhan Ozdemir, Guisen Li, Doru Valceanu, Serhan Tuglular, Valeria Rechnik, Fernando B. Rodrigues, Siren Sezer, Hendrik Veldink, Helena Rotta Pereira, Qiang He, P. Devarajan, Alessandra Chiarini, Ilaria Crespi, G. Cresce

Publikováno v: NDT Plus. 2:ii178-ii178

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ceb3b9771337fad4ac1f9be9d7d57f63
https://doi.org/10.1093/ndtplus/2.s2.42

Effects of hypoxia and hypercapnia on atrial natriuretic factor and plasma renin activity in conscious dogs

Autor: Denise Hartemann, Jean-Paul Clozel, Mustapha Allam, Walter Fischli, Claude Saunier

Publikováno v: Clinical Science. 76:249-254

1. The aim of the present study was to assess the effects of hypercapnia or hypoxia on plasma concentrations of atrial natriuretic factor (ANF) in conscious unrestrained dogs. 2. For this purpose, chronically instrumented dogs were exposed in a rando

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c44bb748322a54193c25cd923e20a6ec
https://doi.org/10.1042/cs0760249