Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Mustafa Zahrittin Kazancioglu"'
Autor:
Mehmet Abdullah Alagöz, Mustafa Zahrittin Kazancioglu, Oztekin Algul, Aylin Döğen, Elif Akin Kazancioglu, Serdar Burmaoglu
The increasing resistance to antimicrobial drugs has instigated the crucial need for the discovery of novel compounds with different modes of action that could target both sensitive and resistant strains. For this purpose, we developed some new chalc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84353358b88b6ae4a4639d029493997c
Two different amino piperazine derivatives bearing various halogen groups were synthesized in high yields and explored in further transformations. Reacting these amino piperazines with various sulfonyl chlorides yielded eight different sulfonamides.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d1552b62f5a0fad026eef07d1281ed4
Publikováno v:
ChemistrySelect. 4:8797-8799
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::657d6f5800b63c02e80551e4c764cfed
https://doi.org/10.1002/slct.201902249
https://doi.org/10.1002/slct.201902249
Publikováno v:
Tetrahedron Letters. 57:5611-5615
The oxidation reactions of various azidoalkyl furans were explored under different conditions to access structurally complex compounds from simple starting materials in an operationally simple, single step reaction. The strategically placed azide fun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3eae599baaabc5a8fb9a18b4de78aab5
https://doi.org/10.1016/j.tetlet.2016.10.116
https://doi.org/10.1016/j.tetlet.2016.10.116
Autor:
Paul A. Johnston, Mustafa Zahrittin Kazancioglu, Benjamin R. Eyer, Erica Parrinello, Dan Wang, Joel B. Nelson, Jianhua Zhou, Kurtis Eisermann, Erin M. Skoda, Zhou Wang, James K. Johnson, Katherine J. O’Malley, Peter Wipf
Publikováno v:
ACS Medicinal Chemistry Letters. 7:785-790
After a high-throughput screening campaign identified thioether 1 as an antagonist of the nuclear androgen receptor, a zone model was developed for structure-activity relationship (SAR) purposes and analogues were synthesized and evaluated in a cell-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91a59f3c6c59672d36f1d453a01e369c
https://doi.org/10.1021/acsmedchemlett.6b00186
https://doi.org/10.1021/acsmedchemlett.6b00186
Autor:
Mustafa Zahrittin Kazancioglu, Ruya Kaya, Muhammet Karaman, İlhami Gülçin, Serdar Burmaoglu, Elif Akin Kazancioglu, Oztekin Algul
Publikováno v:
Journal of Molecular Structure. 1208:127868
Chalcones and their derivatives are increasing attention due to numerous biochemical and pharmacological applications. In this study, a series of novel organohalogen chalcone derivatives (5-12) were tested towards alpha-glycosidase (alpha-Gly), acety
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df65e0454ab971625a541228084d991e
https://doi.org/10.1016/j.molstruc.2020.127868
https://doi.org/10.1016/j.molstruc.2020.127868
Autor:
Meryem Fistikci, Elif Akin Kazancioglu, Hasan Seçen, Mustafa Zahrittin Kazancioglu, Ramazan Altundas
Publikováno v:
Organic Letters. 15:4790-4793
Photooxygenation of azidoalkyl furans has revealed both a novel triazole formation method and a unique endoperoxide rearrangement. The key step of this method is a 3 + 2 cycloaddion of the azide to the endoperoxide intermediate. The reduction of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98757edbd5c596e2b5bb858d6ca5fa23
https://doi.org/10.1021/ol402163u
https://doi.org/10.1021/ol402163u
Publikováno v:
ChemInform. 47
The oxidation reactions of amino and hydroxylamino substituted alkylfurans were explored for the synthesis of structurally complex compounds from simple starting materials. A novel photooxygenation of the furan derivatives gave an α,β-unsaturated d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::123f7615784343c3dfe01f457bdabe45
https://doi.org/10.1002/chin.201614040
https://doi.org/10.1002/chin.201614040
The oxidation reactions of amino and hydroxylamino substituted alkylfurans were explored for the synthesis of structurally complex compounds from simple starting materials. A novel photooxygenation of the furan derivatives gave an alpha,beta-unsatura
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::055a5aacf9ec1415a1e8396e6d9ef3c4
https://aperta.ulakbim.gov.tr/record/82287
https://aperta.ulakbim.gov.tr/record/82287
Publikováno v:
ACS medicinal chemistry letters. 5(8)
Low aqueous solubility is a common challenge in drug discovery and development and can lead to inconclusive biological assay results. Attaching small, polar groups that do not interfere with the bioactivity of the pharmacophore often improves solubil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab3e2bbfa789421c1c7177f61c2190c2
https://pubmed.ncbi.nlm.nih.gov/25147611
https://pubmed.ncbi.nlm.nih.gov/25147611